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Spatial pattern gene: ZNF217 (spascer ID:7764) |
Gene summary for ZNF217 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | ZNF217 | Gene ID | 7764 |
| Gene name | zinc finger protein 217 |
| Synonyms | ZABC1 |
| Cytomap | 20q13.2 |
| Type of gene | protein-coding |
| Description | zinc finger protein 217 |
| Modification date | 20220515 |
| UniProtAcc | O75362 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| ZNF217 | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 21873635 | Function |
| ZNF217 | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| ZNF217 | GO:0005634 | nucleus | 21873635 | Component |
| ZNF217 | GO:0006355 | regulation of transcription, DNA-templated | 21873635 | Process |
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Spatial pattern events for ZNF217 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| ZNF217 | Human | Prostate | rep_9 | 29925878 | 3.09e-06 |
| ZNF217 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| ZNF217 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| ZNF217 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| ZNF217 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| ZNF217 | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| ZNF217 | Human | Uterus | rep_3 | 34857954 | 1.51e-08 |
| ZNF217 | Human | Breast | CID4290 | 34493872 | 8.08e-15 |
| ZNF217 | Human | Breast | CID4535 | 34493872 | 6.14e-11 |
| ZNF217 | Human | Lung | rep_1 | 35355018 | 7.62e-06 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_CID4290_H&E  |  |
Breast_CID4535_H&E  |  |
Lung_rep_1_H&E  |  |
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Spatial pattern pathway has ZNF217 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| ZNF217 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Intestine | A3 | 5.9e-17 |
| ZNF217 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 7.7e-14 |
| ZNF217 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Intestine | A3 | 1.9e-15 |
| ZNF217 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Uterus | rep_26 | 2.1e-06 |
| ZNF217 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Uterus | rep_26 | 6.2e-13 |
| ZNF217 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Breast | rep_6 | 2.6e-08 |
| ZNF217 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_6 | 3.5e-08 |
| ZNF217 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Breast | rep_6 | 8.2e-08 |
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ZNF217 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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ZNF217 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication | ||
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Transcription factor for ZNF217 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| ZNF217 | Uterus | early | Glandular | USP54,ENC1,DUSP16, etc. | 0.294 |
| ZNF217 | Uterus | early | SOX9_LGR5 | USP54,ENC1,DUSP16, etc. | 0.385 |
| ZNF217 | Uterus | early | SOX9 | USP54,ENC1,DUSP16, etc. | 0.472 |
| ZNF217 | Uterus | early_mid | Glandular | DNAJC13,ATP2C1,ZNF532, etc. | 0.383 |
| ZNF217 | Uterus | early_mid | Lumenal 1 | DNAJC13,ATP2C1,ZNF532, etc. | 0.505 |
| ZNF217 | Uterus | early_mid | Glandular_secretory | DNAJC13,ATP2C1,ZNF532, etc. | 0.258 |
| ZNF217 | Uterus | early_mid | Lumenal 2 | DNAJC13,ATP2C1,ZNF532, etc. | 0.258 |
| ZNF217 | Uterus | mid | Glandular_secretory | HIVEP2,SMAD3,ANXA11, etc. | 0.799 |
| ZNF217 | Uterus | proliferative | SOX9 | EHF,TMCC3,EDN1, etc. | 0.483 |
| ZNF217 | Uterus | proliferative | SOX9_LGR5 | EHF,TMCC3,EDN1, etc. | 0.382 |
| ZNF217 | Uterus | proliferative | SOX9_prolif | EHF,TMCC3,EDN1, etc. | 0.275 |
| Motif information. |
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Related Drugs for ZNF217 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ZNF217 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| ZNF217 | C3658266 | Prostatic Cancer, Castration-Resistant | 1 | CTD_human |
| ZNF217 | C3658267 | Prostatic Neoplasms, Castration-Resistant | 1 | CTD_human |
