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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: TRIM26 (spascer ID:7726)

Gene summary for TRIM26

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

TRIM26

Gene ID

7726

Gene nametripartite motif containing 26
SynonymsAFP|RNF95|ZNF173
Cytomap6p22.1
Type of geneprotein-coding
Descriptiontripartite motif-containing protein 26RING finger protein 95acid finger proteinwidely expressed acid zinc finger proteinzinc finger protein 173
Modification date20220513
UniProtAcc

Q12899


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
TRIM26

GO:0005737

cytoplasm

21873635

Component
TRIM26

GO:0010468

regulation of gene expression

21873635

Process
TRIM26

GO:0016567

protein ubiquitination

21873635

Process
TRIM26

GO:0045087

innate immune response

21873635

Process
TRIM26

GO:0051091

positive regulation of DNA-binding transcription factor activity

21873635

Process
TRIM26

GO:0061630

ubiquitin protein ligase activity

21873635

Function

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Spatial pattern events for TRIM26

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
TRIM26HumanIntestinerep_colon2 344172258.12e-16
TRIM26HumanIntestinerep_colon4 344172251.70e-06
TRIM26HumanLiverrep_liver1 344172258.94e-06
TRIM26HumanLiverrep_liver2 344172256.91e-13
TRIM26HumanBreast1160920F 344938725.21e-08

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon2_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Breast_1160920F_H&E
boxplot

boxplot


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Spatial pattern pathway has TRIM26 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
TRIM26GOBP_Positive_Regulation_Of_Molecular_FunctionHumanBrainrep_1 8.7e-71
TRIM26GOBP_Defense_ResponseHumanBrainrep_4 2.2e-20
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanBrainrep_4 1.2e-64
TRIM26GOBP_Innate_Immune_ResponseHumanBrainrep_4 1.2e-64
TRIM26GOBP_Defense_ResponseHumanLiverrep_1 1.3e-59
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanLiverrep_1 4.3e-69
TRIM26GOBP_Innate_Immune_ResponseHumanLiverrep_1 7.3e-68
TRIM26GOBP_Positive_Regulation_Of_Molecular_FunctionHumanLiverrep_1 2.1e-52
TRIM26GOBP_Positive_Regulation_Of_Molecular_FunctionHumanIntestinerep_colon2 2.3e-37
TRIM26GOBP_Defense_ResponseHumanIntestinerep_colon4 2.5e-86
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanIntestinerep_colon4 1.2e-82
TRIM26GOBP_Innate_Immune_ResponseHumanIntestinerep_colon4 3.4e-69
TRIM26GOBP_Biological_Process_Involved_In_Interaction_With_HostHumanIntestineA3 3.9e-17
TRIM26GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanIntestineA3 3.5e-14
TRIM26GOBP_Cytokine_Mediated_Signaling_PathwayHumanIntestineA3 2.6e-09
TRIM26GOBP_Defense_ResponseHumanIntestineA3 6.3e-13
TRIM26GOBP_Entry_Into_HostHumanIntestineA3 5.8e-17
TRIM26GOBP_Negative_Regulation_Of_Viral_Life_CycleHumanIntestineA3 8.9e-07
TRIM26GOBP_Negative_Regulation_Of_Viral_ProcessHumanIntestineA3 4.5e-13
TRIM26GOBP_Positive_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanIntestineA3 6.7e-18
TRIM26GOBP_Positive_Regulation_Of_Molecular_FunctionHumanIntestineA3 2.1e-13
TRIM26GOBP_Protein_Modification_By_Small_Protein_ConjugationHumanIntestineA3 1.2e-13
TRIM26GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalHumanIntestineA3 1.8e-12
TRIM26GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_InteractionHumanIntestineA3 7.3e-15
TRIM26GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanIntestineA3 3.1e-19
TRIM26GOBP_Viral_Life_CycleHumanIntestineA3 1.1e-12
TRIM26GOBP_Viral_Release_From_Host_CellHumanIntestineA3 6.7e-12
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanIntestineA8 5.3e-08
TRIM26GOBP_Interferon_Gamma_Mediated_Signaling_PathwayHumanIntestineA8 2.7e-07
TRIM26GOBP_Negative_Regulation_Of_Viral_Entry_Into_Host_CellHumanIntestineA8 2.5e-17
TRIM26GOBP_Response_To_CytokineHumanIntestineA8 1.6e-08
TRIM26GOBP_Interferon_Gamma_Mediated_Signaling_PathwayHumanPancreasPDAC-A-st2 2.1e-05
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanUterusrep_4 2.0e-31
TRIM26GOBP_Innate_Immune_ResponseHumanUterusrep_4 6.1e-31
TRIM26GOBP_Defense_ResponseHumanUterusrep_1 3.0e-06
TRIM26GOBP_Negative_Regulation_Of_Viral_ProcessHumanUterusrep_1 8.1e-06
TRIM26GOBP_Negative_Regulation_Of_Viral_Entry_Into_Host_CellHumanUterusrep_25 2.7e-06
TRIM26GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanUterusrep_26 5.9e-08
TRIM26GOBP_Cytokine_Mediated_Signaling_PathwayHumanUterusrep_26 2.0e-10
TRIM26GOBP_Interferon_Gamma_Mediated_Signaling_PathwayHumanUterusrep_26 1.3e-08
TRIM26GOBP_Negative_Regulation_Of_Viral_Life_CycleHumanUterusrep_26 1.7e-11
TRIM26GOBP_Protein_Modification_By_Small_Protein_ConjugationHumanUterusrep_26 2.1e-08
TRIM26GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalHumanUterusrep_26 5.7e-08
TRIM26GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_InteractionHumanUterusrep_26 7.0e-07
TRIM26GOBP_Response_To_Interferon_GammaHumanUterusrep_26 5.5e-07
TRIM26GOBP_Viral_Life_CycleHumanUterusrep_26 2.1e-06
TRIM26GOBP_Biological_Process_Involved_In_Interaction_With_HostHumanUterusrep_29 4.0e-06
TRIM26GOBP_Biological_Process_Involved_In_Interaction_With_HostHumanBreastrep_1 1.2e-30
TRIM26GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanBreastrep_1 5.4e-30
TRIM26GOBP_Cytokine_Mediated_Signaling_PathwayHumanBreastrep_11.5e-144
TRIM26GOBP_Defense_ResponseHumanBreastrep_1 1.0e-09
TRIM26GOBP_Entry_Into_HostHumanBreastrep_1 2.3e-32
TRIM26GOBP_Interferon_Gamma_Mediated_Signaling_PathwayHumanBreastrep_1 1.9e-25
TRIM26GOBP_Negative_Regulation_Of_Viral_Entry_Into_Host_CellHumanBreastrep_1 2.8e-82
TRIM26GOBP_Negative_Regulation_Of_Viral_Life_CycleHumanBreastrep_1 1.7e-69
TRIM26GOBP_Negative_Regulation_Of_Viral_ProcessHumanBreastrep_1 3.4e-64
TRIM26GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_InteractionHumanBreastrep_1 1.0e-25
TRIM26GOBP_Response_To_CytokineHumanBreastrep_1 2.5e-24
TRIM26GOBP_Response_To_Interferon_GammaHumanBreastrep_1 1.1e-10
TRIM26GOBP_Viral_Life_CycleHumanBreastrep_1 1.2e-08
TRIM26GOBP_Positive_Regulation_Of_Molecular_FunctionHumanBreastrep_5 7.4e-10
TRIM26GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanBreastrep_5 8.2e-07
TRIM26GOBP_Positive_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanBreastrep_6 2.6e-04
TRIM26GOBP_Protein_Modification_By_Small_Protein_ConjugationHumanBreastrep_6 3.6e-10
TRIM26GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalHumanBreastrep_6 2.7e-09
TRIM26GOBP_Viral_Release_From_Host_CellHumanBreastrep_6 8.4e-04
TRIM26GOBP_Viral_Release_From_Host_CellHumanSkinP2_rep2 3.9e-08
TRIM26GOBP_Biological_Process_Involved_In_Interaction_With_HostHumanSkinP9_rep2 2.5e-08
TRIM26GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanSkinP9_rep2 4.7e-10
TRIM26GOBP_Entry_Into_HostHumanSkinP9_rep2 2.0e-09
TRIM26GOBP_Interferon_Gamma_Mediated_Signaling_PathwayHumanSkinP10_rep2 1.4e-12
TRIM26GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanLungrep_1 2.4e-10
TRIM26GOBP_Defense_ResponseHumanLungrep_1 9.9e-12
TRIM26GOBP_Defense_Response_To_Other_OrganismHumanLungrep_1 1.5e-09
TRIM26GOBP_Negative_Regulation_Of_Viral_ProcessHumanLungrep_1 1.5e-09
TRIM26GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanLungrep_1 1.9e-10
TRIM26GOBP_Viral_Life_CycleHumanLungrep_1 2.0e-16
TRIM26GOBP_Biological_Process_Involved_In_Interaction_With_HostHumanLungrep_2 4.5e-08
TRIM26GOBP_Entry_Into_HostHumanLungrep_2 8.2e-07
TRIM26GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_InteractionHumanLungrep_2 2.7e-08

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TRIM26 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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TRIM26 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for TRIM26 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for TRIM26

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIM26

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource