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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: VEZF1 (spascer ID:7716)

Gene summary for VEZF1

Gene summary

Gene information
	Species	Human
	Gene symbol	VEZF1
	Gene ID	7716
	Gene name	vascular endothelial zinc finger 1
	Synonyms	DB1\|ZNF161
	Cytomap	17q22
	Type of gene	protein-coding
	Description	vascular endothelial zinc finger 1putative transcription factor DB1zinc finger protein 161
	Modification date	20220513
	UniProtAcc	Q14119

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
VEZF1	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	21873635	Function
VEZF1	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
VEZF1	GO:0005634	nucleus	21873635	Component
VEZF1	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for VEZF1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
VEZF1	Human	Brain	rep_10	33558695	3.23e-15
VEZF1	Human	Intestine	rep_colon2	34417225	2.34e-06
VEZF1	Human	Liver	rep_liver1	34417225	1.08e-15
VEZF1	Human	Liver	rep_liver2	34417225	6.98e-16
VEZF1	Human	Breast	CID44971	34493872	9.16e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_10_H&E
Intestine_rep_colon2_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has VEZF1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
VEZF1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
VEZF1	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
VEZF1	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
VEZF1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
VEZF1	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
VEZF1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
VEZF1	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
VEZF1	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
VEZF1	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
VEZF1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
VEZF1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
VEZF1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
VEZF1	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
VEZF1	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
VEZF1	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
VEZF1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
VEZF1	GOBP_Cellular_Defense_Response	Human	Intestine	A8	2.0e-15
VEZF1	GOBP_Endothelial_Cell_Development	Human	Intestine	A8	1.7e-10
VEZF1	GOBP_Epithelial_Cell_Differentiation	Human	Intestine	A8	6.8e-07
VEZF1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Differentiation	Human	Intestine	A8	7.6e-09
VEZF1	GOBP_Regulation_Of_Endothelial_Cell_Differentiation	Human	Intestine	A8	9.6e-09
VEZF1	GOBP_Regulation_Of_Epithelial_Cell_Differentiation	Human	Intestine	A8	2.6e-10
VEZF1	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
VEZF1	GOBP_Epithelial_Cell_Development	Human	Pancreas	PDAC-A-st2	5.9e-05
VEZF1	GOBP_Positive_Regulation_Of_Endothelial_Cell_Differentiation	Human	Pancreas	PDAC-A-st2	4.7e-06
VEZF1	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
VEZF1	GOBP_Cellular_Defense_Response	Human	Uterus	rep_26	8.0e-09
VEZF1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
VEZF1	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
VEZF1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
VEZF1	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
VEZF1	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
VEZF1	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
VEZF1	GOBP_Endothelial_Cell_Development	Human	Breast	rep_1	2.1e-67
VEZF1	GOBP_Endothelium_Development	Human	Breast	rep_1	4.9e-08
VEZF1	GOBP_Epithelial_Cell_Differentiation	Human	Breast	rep_1	4.5e-30
VEZF1	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
VEZF1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
VEZF1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
VEZF1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Differentiation	Human	Breast	rep_1	5.3e-112
VEZF1	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
VEZF1	GOBP_Regulation_Of_Epithelial_Cell_Differentiation	Human	Breast	rep_1	5.9e-91
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
VEZF1	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
VEZF1	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
VEZF1	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
VEZF1	GOBP_Epithelial_Cell_Development	Human	Breast	rep_5	1.8e-05
VEZF1	GOBP_Positive_Regulation_Of_Endothelial_Cell_Differentiation	Human	Breast	rep_5	2.1e-06
VEZF1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
VEZF1	GOBP_Regulation_Of_Endothelial_Cell_Differentiation	Human	Breast	rep_5	6.6e-19
VEZF1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
VEZF1	GOBP_Regulation_Of_Endothelial_Cell_Differentiation	Human	Skin	P5_rep3	2.6e-08
VEZF1	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
VEZF1	GOBP_Positive_Regulation_Of_Endothelial_Cell_Differentiation	Human	Skin	P10_rep3	3.2e-08
VEZF1	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
VEZF1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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VEZF1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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VEZF1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for VEZF1 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Vezf1	Kidney	LPS	TAL	Pacsin3,Crebbp,Vcan, etc.	0.354
Vezf1	Kidney	LPS	CD_IC	Pacsin3,Crebbp,Vcan, etc.	0.308
Vezf1	Kidney	LPS	Endothelial	Pacsin3,Crebbp,Vcan, etc.	0.256
Vezf1	Kidney	LPS	CD_PC	Pacsin3,Crebbp,Vcan, etc.	0.286
Vezf1	Kidney	Sham	PT_S3_OS	Fgf9,Greb1,Efemp1, etc.	0.251
Vezf1	Kidney	Sham	PT_S3_C	Fgf9,Greb1,Efemp1, etc.	0.281
Vezf1	Kidney	Sham	PT_Fibrinogen	Fgf9,Greb1,Efemp1, etc.	0.258
Vezf1	Kidney	Sham	VSM	Fgf9,Greb1,Efemp1, etc.	0.281
Vezf1	Kidney	Sham	TAL	Fgf9,Greb1,Efemp1, etc.	0.394

Motif information.

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Related Drugs for VEZF1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for VEZF1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source