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Spatial pattern gene: MZF1 (spascer ID:7593) |
Gene summary for MZF1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | MZF1 | Gene ID | 7593 |
| Gene name | myeloid zinc finger 1 |
| Synonyms | MZF-1|MZF1B|ZFP98|ZNF42|ZSCAN6 |
| Cytomap | 19q13.43 |
| Type of gene | protein-coding |
| Description | myeloid zinc finger 1zinc finger and SCAN domain-containing protein 6zinc finger protein 42 (myeloid-specific retinoic acid-responsive) |
| Modification date | 20220513 |
| UniProtAcc | P28698 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| MZF1 | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 21873635 | Function |
| MZF1 | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| MZF1 | GO:0006355 | regulation of transcription, DNA-templated | 21873635 | Process |
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Spatial pattern events for MZF1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| MZF1 | Human | Bladder | rep_2 | 34385456 | 2.17e-14 |
| MZF1 | Human | Intestine | rep_colon4 | 34417225 | 2.06e-15 |
| MZF1 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| MZF1 | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| MZF1 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
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Spatial pattern pathway has MZF1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| MZF1 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Intestine | A3 | 5.9e-17 |
| MZF1 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 7.7e-14 |
| MZF1 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Intestine | A3 | 1.9e-15 |
| MZF1 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 5.1e-13 |
| MZF1 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Intestine | A3 | 9.4e-13 |
| MZF1 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Uterus | rep_26 | 2.1e-06 |
| MZF1 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Uterus | rep_26 | 6.2e-13 |
| MZF1 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_5 | 8.0e-09 |
| MZF1 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Breast | rep_6 | 2.6e-08 |
| MZF1 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_6 | 3.5e-08 |
| MZF1 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Breast | rep_6 | 8.2e-08 |
| MZF1 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Breast | rep_6 | 4.2e-06 |
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MZF1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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MZF1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication | ||
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Transcription factor for MZF1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| MZF1 | Uterus | late | Glandular_secretory | NRP1,ERICH3,LCORL, etc. | 0.462 |
| MZF1 | Uterus | late | Ciliated | NRP1,ERICH3,LCORL, etc. | 0.397 |
| MZF1 | Uterus | proliferative | SOX9 | ZFHX2,VDR,DMPK, etc. | 0.368 |
| MZF1 | Uterus | proliferative | Ciliated | ZFHX2,VDR,DMPK, etc. | 0.292 |
| Motif information. |
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Related Drugs for MZF1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MZF1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
