|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: ZNF3 (spascer ID:7551) |
Gene summary for ZNF3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | ZNF3 | Gene ID | 7551 |
| Gene name | zinc finger protein 3 |
| Synonyms | A8-51|HF.12|KOX25|PP838|Zfp113 |
| Cytomap | 7q22.1 |
| Type of gene | protein-coding |
| Description | zinc finger protein 3C2-H2 type zinc finger proteinzinc finger protein HF.12zinc finger protein HZF3.1zinc finger protein KOX25 |
| Modification date | 20220513 |
| UniProtAcc | P17036 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| ZNF3 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 21873635 | Process |
| ZNF3 | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | 21873635 | Function |
| ZNF3 | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| ZNF3 | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | 21873635 | Function |
| ZNF3 | GO:0006357 | regulation of transcription by RNA polymerase II | 21873635 | Process |
Top |
Spatial pattern events for ZNF3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| ZNF3 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| ZNF3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| ZNF3 | Human | Uterus | rep_3 | 34857954 | 3.92e-11 |
| ZNF3 | Human | Breast | CID44971 | 34493872 | 2.93e-10 |
| ZNF3 | Human | Lung | rep_1 | 35355018 | 1.51e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_CID44971_H&E  |  |
Lung_rep_1_H&E  |  |
Top |
Spatial pattern pathway has ZNF3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| ZNF3 | GOBP_Cell_Activation | Human | Intestine | A3 | 6.2e-08 |
| ZNF3 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Intestine | A3 | 5.9e-17 |
| ZNF3 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 7.7e-14 |
| ZNF3 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Intestine | A3 | 1.9e-15 |
| ZNF3 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Uterus | rep_26 | 2.1e-06 |
| ZNF3 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Uterus | rep_26 | 6.2e-13 |
| ZNF3 | GOBP_Cell_Activation | Human | Uterus | rep_28 | 2.5e-06 |
| ZNF3 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Breast | rep_6 | 2.6e-08 |
| ZNF3 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_6 | 3.5e-08 |
| ZNF3 | GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Breast | rep_6 | 8.2e-08 |
| ZNF3 | GOBP_Cell_Activation | Human | Lung | rep_1 | 2.1e-08 |
Top |
ZNF3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
ZNF3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for ZNF3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for ZNF3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for ZNF3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
