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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: C8G (spascer ID:733)

Gene summary for C8G

Gene summary

Gene information
	Species	Human
	Gene symbol	C8G
	Gene ID	733
	Gene name	complement C8 gamma chain
	Synonyms	C8C
	Cytomap	9q34.3
	Type of gene	protein-coding
	Description	complement component C8 gamma chaincomplement component 8, gamma polypeptide
	Modification date	20220513
	UniProtAcc	P07360

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
C8G	GO:0001848	complement binding	21873635	Function

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Spatial pattern events for C8G

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
C8G	Human	Liver	rep_liver1	34417225	1.89e-15
C8G	Human	Liver	rep_liver2	34417225	6.98e-16
C8G	Human	Liver	rep_liver3	34417225	3.51e-15
C8G	Human	Liver	rep_liver4	34417225	7.71e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E

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Spatial pattern pathway has C8G envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
C8G	GOBP_Activation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Adaptive_Immune_Response	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Brain	rep_1	8.1e-16
C8G	GOBP_B_Cell_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Complement_Activation	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Brain	rep_1	1.1e-26
C8G	GOBP_Humoral_Immune_Response	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Lymphocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Positive_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
C8G	GOBP_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
C8G	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
C8G	GOBP_Innate_Immune_Response	Human	Brain	rep_4	1.2e-64
C8G	GOBP_Cytolysis	Human	Brain	rep_12	4.0e-05
C8G	GOBP_Activation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Adaptive_Immune_Response	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Liver	rep_1	2.3e-76
C8G	GOBP_B_Cell_Mediated_Immunity	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Complement_Activation	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Liver	rep_1	1.3e-69
C8G	GOBP_Cytolysis	Human	Liver	rep_1	2.8e-62
C8G	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
C8G	GOBP_Humoral_Immune_Response	Human	Liver	rep_1	9.0e-62
C8G	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
C8G	GOBP_Innate_Immune_Response	Human	Liver	rep_1	7.3e-68
C8G	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
C8G	GOBP_Lymphocyte_Mediated_Immunity	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Positive_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
C8G	GOBP_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
C8G	GOBP_Activation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Adaptive_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_B_Cell_Mediated_Immunity	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Complement_Activation	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
C8G	GOBP_Humoral_Immune_Response	Human	Intestine	rep_colon4	1.3e-27
C8G	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
C8G	GOBP_Innate_Immune_Response	Human	Intestine	rep_colon4	3.4e-69
C8G	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
C8G	GOBP_Lymphocyte_Mediated_Immunity	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
C8G	GOBP_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Intestine	rep_liver3	9.5e-14
C8G	GOBP_Cytolysis	Human	Intestine	rep_liver3	1.5e-08
C8G	GOBP_Activation_Of_Immune_Response	Human	Intestine	A3	5.7e-11
C8G	GOBP_Complement_Activation	Human	Intestine	A3	5.9e-07
C8G	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
C8G	GOBP_Humoral_Immune_Response	Human	Intestine	A3	1.4e-08
C8G	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
C8G	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
C8G	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	A3	2.4e-07
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
C8G	GOBP_Regulation_Of_Immune_Response	Human	Intestine	A3	1.6e-12
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
C8G	GOBP_Adaptive_Immune_Response	Human	Intestine	A8	2.4e-10
C8G	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	A8	1.3e-09
C8G	GOBP_B_Cell_Mediated_Immunity	Human	Intestine	A8	9.3e-10
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
C8G	GOBP_Regulation_Of_Complement_Activation	Human	Intestine	A8	1.6e-14
C8G	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Intestine	A8	2.6e-12
C8G	GOBP_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	2.4e-12
C8G	GOBP_Cytolysis	Human	Uterus	rep_2	1.2e-27
C8G	GOBP_Activation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Adaptive_Immune_Response	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_B_Cell_Mediated_Immunity	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Complement_Activation	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Uterus	rep_4	1.0e-36
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
C8G	GOBP_Humoral_Immune_Response	Human	Uterus	rep_4	2.0e-31
C8G	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
C8G	GOBP_Innate_Immune_Response	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
C8G	GOBP_Lymphocyte_Mediated_Immunity	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Positive_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
C8G	GOBP_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
C8G	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
C8G	GOBP_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	5.1e-07
C8G	GOBP_Regulation_Of_Complement_Activation	Human	Uterus	rep_29	1.3e-08
C8G	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Uterus	rep_29	3.7e-10
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Breast	rep_1	3.0e-236
C8G	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
C8G	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Breast	rep_1	2.0e-67
C8G	GOBP_Cytolysis	Human	Breast	rep_3	2.2e-06
C8G	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Skin	P10_rep1	3.5e-08
C8G	GOBP_Regulation_Of_Complement_Activation	Human	Skin	P10_rep1	7.7e-16
C8G	GOBP_Complement_Activation_Alternative_Pathway	Human	Skin	P10_rep2	1.3e-09
C8G	GOBP_Cytolysis	Human	Lung	rep_1	6.9e-08
C8G	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
C8G	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
C8G	GOBP_Humoral_Immune_Response	Human	Lung	rep_1	1.7e-10
C8G	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
C8G	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
C8G	GOBP_Lymphocyte_Mediated_Immunity	Human	Lung	rep_2	3.7e-07

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C8G function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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C8G function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for C8G envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for C8G

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for C8G

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source