|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: CAPN5 (spascer ID:726) |
Gene summary for CAPN5 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | CAPN5 | Gene ID | 726 |
| Gene name | calpain 5 |
| Synonyms | ADNIV|HTRA3|VRNI|nCL-3 |
| Cytomap | 11q13.5 |
| Type of gene | protein-coding |
| Description | calpain-5calpain htra-3new calpain 3testis tissue sperm-binding protein Li 91mP |
| Modification date | 20220515 |
| UniProtAcc | O15484 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| CAPN5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity | 21873635 | Function |
| CAPN5 | GO:0005737 | cytoplasm | 21873635 | Component |
| CAPN5 | GO:0006508 | proteolysis | 21873635 | Process |
Top |
Spatial pattern events for CAPN5 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| CAPN5 | Human | Bladder | rep_1 | 34385456 | 1.49e-14 |
| CAPN5 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| CAPN5 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| CAPN5 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| CAPN5 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| CAPN5 | Human | Intestine | A1 | 33406409 | 7.77e-08 |
| CAPN5 | Human | Intestine | A2 | 33406409 | 5.11e-11 |
| CAPN5 | Human | Intestine | A4 | 33406409 | 6.69e-13 |
| CAPN5 | Human | Uterus | rep_1 | 34857954 | 2.59e-06 |
| CAPN5 | Human | Uterus | rep_3 | 34857954 | 3.25e-06 |
| CAPN5 | Human | Lung | rep_1 | 35355018 | 2.31e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_1_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Intestine_A4_H&E  |  |
Uterus_rep_1_H&E  |  |
Uterus_rep_3_H&E  |  |
Lung_rep_1_H&E  |  |
Top |
Spatial pattern pathway has CAPN5 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| CAPN5 | GOBP_Proteolysis | Human | Brain | rep_4 | 1.6e-22 |
| CAPN5 | GOBP_Proteolysis | Human | Liver | rep_1 | 4.2e-73 |
| CAPN5 | GOBP_Proteolysis | Human | Intestine | rep_colon4 | 2.4e-90 |
| CAPN5 | GOBP_Proteolysis | Human | Intestine | A3 | 7.3e-12 |
| CAPN5 | GOBP_Proteolysis | Human | Breast | rep_5 | 1.8e-07 |
Top |
CAPN5 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
CAPN5 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for CAPN5 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for CAPN5 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for CAPN5 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| CAPN5 | C0242852 | Proliferative vitreoretinopathy | 1 | CTD_human;ORPHANET;UNIPROT |
| CAPN5 | C4721549 | Autosomal dominant neovascular inflammatory vitreoretinopathy | 1 | ORPHANET |
