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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: C1QB (spascer ID:713)

Gene summary for C1QB

Gene summary

Gene information
	Species	Human
	Gene symbol	C1QB
	Gene ID	713
	Gene name	complement C1q B chain
	Synonyms	-
	Cytomap	1p36.12
	Type of gene	protein-coding
	Description	complement C1q subcomponent subunit Bcomplement C1q chain Bcomplement component 1, q subcomponent, B chaincomplement component 1, q subcomponent, beta polypeptidecomplement component C1q, B chaincomplement subcomponent C1q chain B
	Modification date	20220513
	UniProtAcc	P02746

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for C1QB

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
C1QB	Human	Brain	rep_3	33558695	1.10e-06
C1QB	Human	Brain	rep_4	33558695	7.26e-06
C1QB	Human	Brain	rep_9	33558695	3.50e-14
C1QB	Human	Brain	rep_10	33558695	3.23e-15
C1QB	Human	Brain	rep_12	33558695	1.03e-11
C1QB	Human	Prostate	rep_3	29925878	6.77e-08
C1QB	Human	Prostate	rep_4	29925878	6.85e-07
C1QB	Human	Bladder	rep_1	34385456	8.93e-15
C1QB	Human	Bladder	rep_2	34385456	6.29e-15
C1QB	Human	Intestine	rep_colon1	34417225	1.95e-15
C1QB	Human	Intestine	rep_colon2	34417225	8.12e-16
C1QB	Human	Intestine	rep_colon3	34417225	1.01e-15
C1QB	Human	Intestine	rep_colon4	34417225	1.14e-15
C1QB	Human	Liver	rep_liver1	34417225	3.57e-15
C1QB	Human	Liver	rep_liver2	34417225	1.27e-15
C1QB	Human	Liver	rep_liver3	34417225	3.51e-15
C1QB	Human	Liver	rep_liver4	34417225	7.71e-16
C1QB	Human	Intestine	A1	33406409	2.09e-15
C1QB	Human	Intestine	A2	33406409	3.85e-15
C1QB	Human	Intestine	A3	33406409	5.23e-09
C1QB	Human	Intestine	A4	33406409	9.63e-15
C1QB	Human	Pancreas	PDAC-B-st1	31932730	3.76e-06
C1QB	Human	Pancreas	PDAC-D-st1	31932730	7.91e-11
C1QB	Human	Uterus	rep_2	34857954	6.03e-07
C1QB	Human	Uterus	rep_3	34857954	1.66e-15
C1QB	Human	Breast	A1	34650042	1.02e-06
C1QB	Human	Breast	A3	34650042	4.60e-06
C1QB	Human	Breast	A4	34650042	1.01e-11
C1QB	Human	Breast	A5	34650042	1.29e-13
C1QB	Human	Breast	C4	34650042	3.43e-08
C1QB	Human	Breast	D2	34650042	1.06e-13
C1QB	Human	Breast	D3	34650042	1.39e-13
C1QB	Human	Breast	D4	34650042	1.22e-13
C1QB	Human	Breast	D5	34650042	3.25e-13
C1QB	Human	Breast	D6	34650042	2.97e-09
C1QB	Human	Breast	E2	34650042	1.43e-08
C1QB	Human	Breast	E3	34650042	6.04e-07
C1QB	Human	Breast	F1	34650042	2.45e-08
C1QB	Human	Breast	F2	34650042	2.01e-09
C1QB	Human	Breast	F3	34650042	5.68e-14
C1QB	Human	Breast	G1	34650042	7.94e-06
C1QB	Human	Breast	G2	34650042	3.97e-08
C1QB	Human	Breast	G3	34650042	7.07e-07
C1QB	Human	Breast	H1	34650042	1.28e-11
C1QB	Human	Breast	H2	34650042	5.00e-10
C1QB	Human	Breast	1142243F	34493872	2.30e-15
C1QB	Human	Breast	1160920F	34493872	1.48e-15
C1QB	Human	Breast	CID4290	34493872	4.68e-15
C1QB	Human	Breast	CID4465	34493872	4.85e-15
C1QB	Human	Breast	CID44971	34493872	1.76e-15
C1QB	Human	Breast	CID4535	34493872	6.37e-15
C1QB	Human	Skin	P2_rep1	32946785	5.41e-15
C1QB	Human	Skin	P2_rep2	32946785	5.48e-15
C1QB	Human	Skin	P2_rep3	32946785	5.90e-15
C1QB	Human	Skin	P5_rep1	32946785	1.61e-06
C1QB	Human	Skin	mel1_rep2	30154148	4.62e-13
C1QB	Human	Skin	mel2_rep1	30154148	3.28e-14
C1QB	Human	Skin	mel2_rep2	30154148	4.08e-14
C1QB	Human	Lung	rep_1	35355018	4.99e-15
C1QB	Human	Lung	rep_2	35355018	1.83e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_12_H&E
Bladder_rep_1_H&E
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A3_H&E
Intestine_A4_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_A1_H&E
Breast_A3_H&E
Breast_A4_H&E
Breast_A5_H&E
Breast_C4_H&E
Breast_D2_H&E
Breast_D3_H&E
Breast_D4_H&E
Breast_D5_H&E
Breast_D6_H&E
Breast_E2_H&E
Breast_E3_H&E
Breast_F1_H&E
Breast_F2_H&E
Breast_F3_H&E
Breast_G1_H&E
Breast_G2_H&E
Breast_G3_H&E
Breast_H1_H&E
Breast_H2_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Skin_P5_rep1_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has C1QB envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
C1QB	GOBP_Activation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Adaptive_Immune_Response	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_B_Cell_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Complement_Activation	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Humoral_Immune_Response	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Lymphocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Positive_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
C1QB	GOBP_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
C1QB	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
C1QB	GOBP_Innate_Immune_Response	Human	Brain	rep_4	1.2e-64
C1QB	GOBP_Activation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Adaptive_Immune_Response	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_B_Cell_Mediated_Immunity	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Complement_Activation	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
C1QB	GOBP_Humoral_Immune_Response	Human	Liver	rep_1	9.0e-62
C1QB	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
C1QB	GOBP_Innate_Immune_Response	Human	Liver	rep_1	7.3e-68
C1QB	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
C1QB	GOBP_Lymphocyte_Mediated_Immunity	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Positive_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
C1QB	GOBP_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
C1QB	GOBP_Activation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Adaptive_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_B_Cell_Mediated_Immunity	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Complement_Activation	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
C1QB	GOBP_Humoral_Immune_Response	Human	Intestine	rep_colon4	1.3e-27
C1QB	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
C1QB	GOBP_Innate_Immune_Response	Human	Intestine	rep_colon4	3.4e-69
C1QB	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
C1QB	GOBP_Lymphocyte_Mediated_Immunity	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
C1QB	GOBP_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
C1QB	GOBP_Synapse_Pruning	Human	Intestine	A1	7.9e-20
C1QB	GOBP_Activation_Of_Immune_Response	Human	Intestine	A3	5.7e-11
C1QB	GOBP_Cell_Junction_Organization	Human	Intestine	A3	1.1e-08
C1QB	GOBP_Cellular_Component_Disassembly	Human	Intestine	A3	1.0e-14
C1QB	GOBP_Complement_Activation	Human	Intestine	A3	5.9e-07
C1QB	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
C1QB	GOBP_Humoral_Immune_Response	Human	Intestine	A3	1.4e-08
C1QB	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
C1QB	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
C1QB	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	A3	2.4e-07
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
C1QB	GOBP_Regulation_Of_Immune_Response	Human	Intestine	A3	1.6e-12
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
C1QB	GOBP_Adaptive_Immune_Response	Human	Intestine	A8	2.4e-10
C1QB	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	A8	1.3e-09
C1QB	GOBP_B_Cell_Mediated_Immunity	Human	Intestine	A8	9.3e-10
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
C1QB	GOBP_Regulation_Of_Complement_Activation	Human	Intestine	A8	1.6e-14
C1QB	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Intestine	A8	2.6e-12
C1QB	GOBP_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	2.4e-12
C1QB	GOBP_Activation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Adaptive_Immune_Response	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_B_Cell_Mediated_Immunity	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Complement_Activation	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
C1QB	GOBP_Humoral_Immune_Response	Human	Uterus	rep_4	2.0e-31
C1QB	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
C1QB	GOBP_Innate_Immune_Response	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
C1QB	GOBP_Lymphocyte_Mediated_Immunity	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Positive_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
C1QB	GOBP_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
C1QB	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
C1QB	GOBP_Cellular_Component_Disassembly	Human	Uterus	rep_26	2.7e-06
C1QB	GOBP_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	5.1e-07
C1QB	GOBP_Regulation_Of_Complement_Activation	Human	Uterus	rep_29	1.3e-08
C1QB	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Uterus	rep_29	3.7e-10
C1QB	GOBP_Cell_Junction_Organization	Human	Breast	rep_1	3.0e-10
C1QB	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
C1QB	GOBP_Regulation_Of_Humoral_Immune_Response	Human	Breast	rep_1	2.0e-67
C1QB	GOBP_Synapse_Organization	Human	Breast	rep_1	3.0e-09
C1QB	GOBP_Cellular_Component_Disassembly	Human	Breast	rep_5	2.0e-06
C1QB	GOBP_Humoral_Immune_Response_Mediated_By_Circulating_Immunoglobulin	Human	Skin	P10_rep1	3.5e-08
C1QB	GOBP_Regulation_Of_Complement_Activation	Human	Skin	P10_rep1	7.7e-16
C1QB	GOBP_Synapse_Pruning	Human	Skin	P10_rep2	3.2e-10
C1QB	GOBP_Cell_Junction_Disassembly	Human	Lung	rep_1	2.8e-08
C1QB	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
C1QB	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
C1QB	GOBP_Humoral_Immune_Response	Human	Lung	rep_1	1.7e-10
C1QB	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
C1QB	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
C1QB	GOBP_Synapse_Pruning	Human	Lung	rep_1	1.1e-08
C1QB	GOBP_Cellular_Component_Disassembly	Human	Lung	rep_2	5.6e-07
C1QB	GOBP_Lymphocyte_Mediated_Immunity	Human	Lung	rep_2	3.7e-07

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C1QB function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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C1QB function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
C1QB	LRP1	C1QB_LRP1	Intestine	A1

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Transcription factor for C1QB envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for C1QB

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for C1QB

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source