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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: KLF5 (spascer ID:688)

Gene summary for KLF5

Gene summary

Gene information
	Species	Human
	Gene symbol	KLF5
	Gene ID	688
	Gene name	Kruppel like factor 5
	Synonyms	BTEB2\|CKLF\|IKLF
	Cytomap	13q22.1
	Type of gene	protein-coding
	Description	Krueppel-like factor 5(intestinal Kruppel-like factorBTE-binding protein 2GC box binding protein 2Kruppel-like factor 5 (intestinal)basic transcription element binding protein 2colon krueppel-like factorcolon kruppel-like factorepididymis secretor
	Modification date	20220515
	UniProtAcc	Q13887

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
KLF5	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	21873635	Function
KLF5	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
KLF5	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for KLF5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
KLF5	Human	Prostate	rep_7	29925878	1.06e-14
KLF5	Human	Bladder	rep_1	34385456	3.65e-13
KLF5	Human	Intestine	rep_colon1	34417225	1.95e-15
KLF5	Human	Intestine	rep_colon2	34417225	1.48e-15
KLF5	Human	Intestine	rep_colon4	34417225	1.14e-15
KLF5	Human	Liver	rep_liver1	34417225	1.08e-15
KLF5	Human	Liver	rep_liver2	34417225	1.27e-15
KLF5	Human	Liver	rep_liver4	34417225	7.71e-16
KLF5	Human	Intestine	A1	33406409	2.09e-15
KLF5	Human	Intestine	A2	33406409	2.47e-15
KLF5	Human	Intestine	A3	33406409	1.38e-14
KLF5	Human	Intestine	A4	33406409	7.35e-15
KLF5	Human	Intestine	A6	33406409	8.35e-11
KLF5	Human	Intestine	A7	33406409	3.34e-06
KLF5	Human	Intestine	A8	33406409	2.47e-14
KLF5	Human	Intestine	A9	33406409	2.99e-14
KLF5	Human	Pancreas	PDAC-D-st1	31932730	3.61e-06
KLF5	Human	Uterus	rep_2	34857954	2.55e-15
KLF5	Human	Uterus	rep_3	34857954	1.11e-07
KLF5	Human	Breast	1142243F	34493872	2.30e-15
KLF5	Human	Breast	CID4465	34493872	7.83e-15
KLF5	Human	Breast	CID44971	34493872	1.76e-15
KLF5	Human	Skin	P2_rep1	32946785	1.56e-14
KLF5	Human	Skin	P2_rep2	32946785	9.08e-15
KLF5	Human	Skin	P2_rep3	32946785	9.21e-15
KLF5	Human	Lung	rep_1	35355018	4.99e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_1_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A3_H&E
Intestine_A4_H&E
Intestine_A6_H&E
Intestine_A7_H&E
Intestine_A8_H&E
Intestine_A9_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_1142243F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Skin_P2_rep3_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has KLF5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
KLF5	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Growth	Human	Brain	rep_4	1.0e-14
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
KLF5	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
KLF5	GOBP_Positive_Regulation_Of_Fat_Cell_Differentiation	Human	Brain	st	4.5e-22
KLF5	GOBP_Regulation_Of_Fat_Cell_Differentiation	Human	Brain	st	1.2e-07
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
KLF5	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
KLF5	GOBP_Regulation_Of_Microvillus_Assembly	Human	Bladder	rep_2	1.6e-04
KLF5	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
KLF5	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
KLF5	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Growth	Human	Liver	rep_1	2.1e-52
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
KLF5	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
KLF5	GOBP_Growth	Human	Intestine	rep_colon2	1.5e-57
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
KLF5	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
KLF5	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
KLF5	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
KLF5	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
KLF5	GOBP_Cell_Projection_Assembly	Human	Intestine	A3	4.9e-09
KLF5	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
KLF5	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
KLF5	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	2.5e-14
KLF5	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
KLF5	GOBP_Developmental_Growth	Human	Intestine	A3	7.3e-10
KLF5	GOBP_Growth	Human	Intestine	A3	3.3e-16
KLF5	GOBP_Myotube_Differentiation	Human	Intestine	A3	2.0e-10
KLF5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
KLF5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
KLF5	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
KLF5	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
KLF5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
KLF5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
KLF5	GOBP_Regeneration	Human	Intestine	A3	5.3e-11
KLF5	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
KLF5	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Intestine	A3	4.1e-07
KLF5	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
KLF5	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
KLF5	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
KLF5	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
KLF5	GOBP_Tissue_Regeneration	Human	Intestine	A3	1.0e-08
KLF5	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
KLF5	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
KLF5	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
KLF5	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
KLF5	GOBP_Cellular_Response_To_Peptide	Human	Intestine	A8	2.9e-08
KLF5	GOBP_Columnar_Cuboidal_Epithelial_Cell_Development	Human	Intestine	A8	2.4e-07
KLF5	GOBP_Epithelial_Cell_Differentiation	Human	Intestine	A8	6.8e-07
KLF5	GOBP_Fat_Cell_Differentiation	Human	Intestine	A8	2.4e-24
KLF5	GOBP_Intestinal_Epithelial_Cell_Development	Human	Intestine	A8	1.2e-15
KLF5	GOBP_Intestinal_Epithelial_Cell_Differentiation	Human	Intestine	A8	1.7e-10
KLF5	GOBP_Microvillus_Assembly	Human	Intestine	A8	1.9e-12
KLF5	GOBP_Myotube_Differentiation_Involved_In_Skeletal_Muscle_Regeneration	Human	Intestine	A8	3.7e-10
KLF5	GOBP_Positive_Regulation_Of_Fat_Cell_Differentiation	Human	Intestine	A8	3.4e-18
KLF5	GOBP_Regulation_Of_Fat_Cell_Differentiation	Human	Intestine	A8	5.6e-17
KLF5	GOBP_Regulation_Of_Microvillus_Assembly	Human	Intestine	A8	1.1e-19
KLF5	GOBP_Response_To_Cytokine	Human	Intestine	A8	1.6e-08
KLF5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Intestine	A8	1.9e-11
KLF5	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
KLF5	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
KLF5	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Intestine	A8	1.4e-29
KLF5	GOBP_Skeletal_Muscle_Organ_Development	Human	Intestine	A8	2.2e-39
KLF5	GOBP_Skeletal_Muscle_Satellite_Cell_Activation	Human	Intestine	A8	2.2e-16
KLF5	GOBP_Skeletal_Muscle_Satellite_Cell_Differentiation	Human	Intestine	A8	1.8e-14
KLF5	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
KLF5	GOBP_Positive_Regulation_Of_Fat_Cell_Differentiation	Human	Pancreas	PDAC-B-st1	8.5e-05
KLF5	GOBP_Regeneration	Human	Pancreas	PDAC-B-st1	6.7e-06
KLF5	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Pancreas	PDAC-B-st1	2.2e-05
KLF5	GOBP_Skeletal_Muscle_Tissue_Regeneration	Human	Pancreas	PDAC-B-st1	6.1e-06
KLF5	GOBP_Epithelial_Cell_Development	Human	Pancreas	PDAC-A-st2	5.9e-05
KLF5	GOBP_Regulation_Of_Microvillus_Assembly	Human	Uterus	rep_1	1.7e-06
KLF5	GOBP_Intestinal_Epithelial_Cell_Development	Human	Uterus	rep_25	3.6e-07
KLF5	GOBP_Intestinal_Epithelial_Cell_Differentiation	Human	Uterus	rep_25	4.1e-06
KLF5	GOBP_Skeletal_Muscle_Organ_Development	Human	Uterus	rep_25	7.4e-10
KLF5	GOBP_Skeletal_Muscle_Tissue_Regeneration	Human	Uterus	rep_25	7.1e-08
KLF5	GOBP_Developmental_Growth	Human	Uterus	rep_26	3.8e-06
KLF5	GOBP_Fat_Cell_Differentiation	Human	Uterus	rep_26	3.8e-14
KLF5	GOBP_Muscle_Organ_Development	Human	Uterus	rep_26	6.5e-08
KLF5	GOBP_Muscle_Tissue_Development	Human	Uterus	rep_26	1.2e-10
KLF5	GOBP_Myotube_Differentiation	Human	Uterus	rep_26	3.3e-12
KLF5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
KLF5	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
KLF5	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
KLF5	GOBP_Regulation_Of_Microvillus_Organization	Human	Uterus	rep_26	4.8e-15
KLF5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Uterus	rep_26	4.5e-06
KLF5	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Uterus	rep_26	3.3e-06
KLF5	GOBP_Tissue_Regeneration	Human	Uterus	rep_26	6.9e-17
KLF5	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
KLF5	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
KLF5	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
KLF5	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
KLF5	GOBP_Cell_Projection_Assembly	Human	Breast	rep_1	1.9e-26
KLF5	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
KLF5	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
KLF5	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
KLF5	GOBP_Epithelial_Cell_Differentiation	Human	Breast	rep_1	4.5e-30
KLF5	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
KLF5	GOBP_Fat_Cell_Differentiation	Human	Breast	rep_1	1.1e-26
KLF5	GOBP_Microvillus_Assembly	Human	Breast	rep_1	3.0e-54
KLF5	GOBP_Microvillus_Organization	Human	Breast	rep_1	1.9e-36
KLF5	GOBP_Muscle_Cell_Differentiation	Human	Breast	rep_1	2.9e-50
KLF5	GOBP_Muscle_Organ_Development	Human	Breast	rep_1	1.5e-42
KLF5	GOBP_Muscle_Structure_Development	Human	Breast	rep_1	6.8e-61
KLF5	GOBP_Muscle_Tissue_Development	Human	Breast	rep_1	1.0e-09
KLF5	GOBP_Myotube_Differentiation	Human	Breast	rep_1	9.8e-75
KLF5	GOBP_Myotube_Differentiation_Involved_In_Skeletal_Muscle_Regeneration	Human	Breast	rep_1	1.0e-157
KLF5	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
KLF5	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
KLF5	GOBP_Positive_Regulation_Of_Fat_Cell_Differentiation	Human	Breast	rep_1	1.3e-68
KLF5	GOBP_Regeneration	Human	Breast	rep_1	2.9e-06
KLF5	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
KLF5	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Breast	rep_1	6.5e-29
KLF5	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
KLF5	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
KLF5	GOBP_Regulation_Of_Microvillus_Assembly	Human	Breast	rep_1	1.1e-56
KLF5	GOBP_Regulation_Of_Microvillus_Organization	Human	Breast	rep_1	1.1e-20
KLF5	GOBP_Response_To_Cytokine	Human	Breast	rep_1	2.5e-24
KLF5	GOBP_Skeletal_Muscle_Satellite_Cell_Activation	Human	Breast	rep_1	4.0e-156
KLF5	GOBP_Skeletal_Muscle_Satellite_Cell_Differentiation	Human	Breast	rep_1	6.8e-27
KLF5	GOBP_Skeletal_Muscle_Tissue_Regeneration	Human	Breast	rep_1	7.6e-150
KLF5	GOBP_Striated_Muscle_Cell_Differentiation	Human	Breast	rep_1	2.1e-49
KLF5	GOBP_Tissue_Regeneration	Human	Breast	rep_1	3.2e-66
KLF5	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
KLF5	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
KLF5	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
KLF5	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
KLF5	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	5.1e-18
KLF5	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
KLF5	GOBP_Developmental_Growth	Human	Breast	rep_5	1.6e-08
KLF5	GOBP_Epithelial_Cell_Development	Human	Breast	rep_5	1.8e-05
KLF5	GOBP_Growth	Human	Breast	rep_5	5.4e-12
KLF5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
KLF5	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
KLF5	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
KLF5	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
KLF5	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
KLF5	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Breast	rep_5	4.2e-04
KLF5	GOBP_Skeletal_Muscle_Organ_Development	Human	Breast	rep_5	5.2e-09
KLF5	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
KLF5	GOBP_Cellular_Response_To_Peptide	Human	Breast	rep_6	8.4e-11
KLF5	GOBP_Columnar_Cuboidal_Epithelial_Cell_Development	Human	Breast	rep_6	1.5e-10
KLF5	GOBP_Columnar_Cuboidal_Epithelial_Cell_Differentiation	Human	Breast	rep_6	3.0e-04
KLF5	GOBP_Intestinal_Epithelial_Cell_Development	Human	Breast	rep_6	1.4e-05
KLF5	GOBP_Intestinal_Epithelial_Cell_Differentiation	Human	Breast	rep_6	1.3e-04
KLF5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
KLF5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
KLF5	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
KLF5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
KLF5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Breast	rep_6	4.6e-06
KLF5	GOBP_Regeneration	Human	Skin	P2_rep2	5.2e-08
KLF5	GOBP_Skeletal_Muscle_Organ_Development	Human	Skin	P5_rep1	8.8e-12
KLF5	GOBP_Columnar_Cuboidal_Epithelial_Cell_Development	Human	Skin	P5_rep3	5.9e-11
KLF5	GOBP_Intestinal_Epithelial_Cell_Differentiation	Human	Skin	P5_rep3	1.2e-08
KLF5	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
KLF5	GOBP_Columnar_Cuboidal_Epithelial_Cell_Differentiation	Human	Skin	P10_rep3	5.0e-21
KLF5	GOBP_Skeletal_Muscle_Tissue_Regeneration	Human	Skin	P10_rep3	1.2e-14
KLF5	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
KLF5	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
KLF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08

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KLF5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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KLF5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for KLF5 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Klf5	Kidney	LPS	PT_S3_OS	Slc39a4,Plekhs1,Mgl2, etc.	0.309
Klf5	Kidney	LPS	TAL	Slc39a4,Plekhs1,Mgl2, etc.	0.328
Klf5	Kidney	LPS	CNT	Slc39a4,Plekhs1,Mgl2, etc.	0.263
Klf5	Kidney	LPS	PT_S2	Slc39a4,Plekhs1,Mgl2, etc.	0.265
Klf5	Kidney	LPS	PT_S3_C	Slc39a4,Plekhs1,Mgl2, etc.	0.318
KLF5	Uterus	early	Glandular	NEDD9,ARL4C,DSP, etc.	0.33
KLF5	Uterus	early	Glandular_secretory	NEDD9,ARL4C,DSP, etc.	0.257
KLF5	Uterus	early	SOX9_LGR5	NEDD9,ARL4C,DSP, etc.	0.374
KLF5	Uterus	early	SOX9	NEDD9,ARL4C,DSP, etc.	0.465
KLF5	Uterus	early_mid	Glandular	DSP,PTP4A1,KLF6, etc.	0.361
KLF5	Uterus	early_mid	Lumenal 1	DSP,PTP4A1,KLF6, etc.	0.52
KLF5	Uterus	early_mid	Glandular_secretory	DSP,PTP4A1,KLF6, etc.	0.25
KLF5	Uterus	early_mid	Lumenal 2	DSP,PTP4A1,KLF6, etc.	0.266
KLF5	Pancreas	patientB	Cancer clone A	EZR,ONECUT2,YWHAZ, etc.	0.339
KLF5	Pancreas	patientB	Ductal_terminal ductal like	EZR,ONECUT2,YWHAZ, etc.	0.509
KLF5	Skin	control	Normal_KC_Basal	DEGS1,PERP,GATA3, etc.	0.345
KLF5	Skin	control	Normal_KC_Diff	DEGS1,PERP,GATA3, etc.	0.51
KLF5	Skin	control	Normal_KC_Cyc	DEGS1,PERP,GATA3, etc.	0.267
KLF5	Uterus	mid	Glandular_secretory	UGCG,ELL2,LMO7, etc.	0.808
KLF5	Intestine	development	Epithelium	FABP1,S100A10,KRT19, etc.	0.491
KLF5	Intestine	development	Fibroblasts	FABP1,S100A10,KRT19, etc.	0.399
KLF5	Intestine	development	MyoFibroblasts	FABP1,S100A10,KRT19, etc.	0.267
KLF5	Skin	tumor	Tumor_KC_Diff	DEGS1,DSP,EHF, etc.	0.305
KLF5	Skin	tumor	Keratinocyte	DEGS1,DSP,EHF, etc.	0.439
KLF5	Skin	tumor	Tumor_KC_Basal	DEGS1,DSP,EHF, etc.	0.255
KLF5	Skin	tumor	CD1C	DEGS1,DSP,EHF, etc.	0.265
Klf5	Kidney	IRI	PT_S1	Slc4a11,Wnt7b,Krt8, etc.	0.302
Klf5	Kidney	IRI	CNT	Slc4a11,Wnt7b,Krt8, etc.	0.251
Klf5	Kidney	IRI	PT_S3_C	Slc4a11,Wnt7b,Krt8, etc.	0.284
Klf5	Kidney	IRI	PT_Fibrinogen	Slc4a11,Wnt7b,Krt8, etc.	0.269
Klf5	Kidney	IRI	CD_IC	Slc4a11,Wnt7b,Krt8, etc.	0.272
Klf5	Kidney	IRI	TAL	Slc4a11,Wnt7b,Krt8, etc.	0.291
Klf5	Kidney	IRI	CD_PC	Slc4a11,Wnt7b,Krt8, etc.	0.273
KLF5	Uterus	proliferative	SOX9	ERRFI1,PMAIP1,UGCG, etc.	0.559
KLF5	Uterus	proliferative	SOX9_LGR5	ERRFI1,PMAIP1,UGCG, etc.	0.338
KLF5	Uterus	proliferative	SOX9_prolif	ERRFI1,PMAIP1,UGCG, etc.	0.331

Motif information.

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Related Drugs for KLF5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for KLF5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
KLF5	C0005684	Malignant neoplasm of urinary bladder	1	CTD_human
KLF5	C0005695	Bladder Neoplasm	1	CTD_human
KLF5	C0007137	Squamous cell carcinoma	1	CTD_human
KLF5	C0009402	Colorectal Carcinoma	1	CTD_human;UNIPROT
KLF5	C0009404	Colorectal Neoplasms	1	CTD_human
KLF5	C0024117	Chronic Obstructive Airway Disease	1	CTD_human
KLF5	C0030297	Pancreatic Neoplasm	1	CTD_human
KLF5	C0036341	Schizophrenia	1	PSYGENET
KLF5	C0152013	Adenocarcinoma of lung (disorder)	1	CTD_human
KLF5	C0346647	Malignant neoplasm of pancreas	1	CTD_human
KLF5	C1527303	Chronic Airflow Obstruction	1	CTD_human
KLF5	C2936380	Neointima	1	CTD_human
KLF5	C2936381	Neointima Formation	1	CTD_human