Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: BNIP3L (spascer ID:665)

Gene summary for BNIP3L

Gene summary

Gene information
	Species	Human
	Gene symbol	BNIP3L
	Gene ID	665
	Gene name	BCL2 interacting protein 3 like
	Synonyms	BNIP3a\|NIX
	Cytomap	8p21.2
	Type of gene	protein-coding
	Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-likeBCL2/adenovirus E1B 19 kDa protein-interacting protein 3ABCL2/adenovirus E1B 19-kd protein-interacting protein 3aBCL2/adenovirus E1B 19kDa interacting protein 3 likeNIP-3-like protein XNIP3
	Modification date	20220513
	UniProtAcc	O60238

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
BNIP3L	GO:0005634	nucleus	21873635	Component
BNIP3L	GO:0005635	nuclear envelope	21873635	Component
BNIP3L	GO:0005741	mitochondrial outer membrane	21873635	Component
BNIP3L	GO:0005783	endoplasmic reticulum	21873635	Component
BNIP3L	GO:0043067	regulation of programmed cell death	21873635	Process
BNIP3L	GO:0051607	defense response to virus	21873635	Process
BNIP3L	GO:0097345	mitochondrial outer membrane permeabilization	21873635	Process

Top

Spatial pattern events for BNIP3L

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
BNIP3L	Human	Intestine	rep_colon1	34417225	5.36e-10
BNIP3L	Human	Intestine	rep_colon2	34417225	8.12e-16
BNIP3L	Human	Intestine	rep_colon3	34417225	3.17e-07
BNIP3L	Human	Liver	rep_liver1	34417225	7.03e-09
BNIP3L	Human	Liver	rep_liver2	34417225	6.98e-16
BNIP3L	Human	Liver	rep_liver3	34417225	4.11e-07
BNIP3L	Human	Intestine	A2	33406409	7.91e-06
BNIP3L	Human	Intestine	A6	33406409	8.31e-06
BNIP3L	Human	Uterus	rep_2	34857954	2.55e-15
BNIP3L	Human	Uterus	rep_3	34857954	3.02e-15
BNIP3L	Human	Uterus	rep_4	34857954	1.82e-15
BNIP3L	Human	Breast	1142243F	34493872	7.88e-15
BNIP3L	Human	Breast	CID44971	34493872	1.76e-15
BNIP3L	Human	Skin	P2_rep1	32946785	1.56e-14
BNIP3L	Human	Skin	P2_rep2	32946785	9.08e-15
BNIP3L	Human	Skin	P2_rep3	32946785	9.21e-15
BNIP3L	Human	Skin	P10_rep2	32946785	2.52e-09
BNIP3L	Human	Skin	P10_rep3	32946785	2.34e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Intestine_A2_H&E
Intestine_A6_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_1142243F_H&E
Breast_CID44971_H&E
Skin_P2_rep3_H&E
Skin_P10_rep2_H&E
Skin_P10_rep3_H&E

Top

Spatial pattern pathway has BNIP3L envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
BNIP3L	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
BNIP3L	GOBP_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
BNIP3L	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
BNIP3L	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
BNIP3L	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
BNIP3L	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
BNIP3L	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
BNIP3L	GOBP_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
BNIP3L	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
BNIP3L	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
BNIP3L	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
BNIP3L	GOBP_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
BNIP3L	GOBP_Apoptotic_Mitochondrial_Changes	Human	Intestine	A3	1.6e-16
BNIP3L	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
BNIP3L	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
BNIP3L	GOBP_Cellular_Component_Disassembly	Human	Intestine	A3	1.0e-14
BNIP3L	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
BNIP3L	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
BNIP3L	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Intestine	A3	2.0e-11
BNIP3L	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
BNIP3L	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
BNIP3L	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Intestine	A3	3.8e-08
BNIP3L	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
BNIP3L	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
BNIP3L	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
BNIP3L	GOBP_Macroautophagy	Human	Intestine	A3	2.3e-07
BNIP3L	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
BNIP3L	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
BNIP3L	GOBP_Mitochondrial_Membrane_Organization	Human	Intestine	A3	1.0e-17
BNIP3L	GOBP_Mitochondrial_Outer_Membrane_Permeabilization	Human	Intestine	A3	1.1e-15
BNIP3L	GOBP_Mitochondrial_Transport	Human	Intestine	A3	9.8e-16
BNIP3L	GOBP_Mitochondrion_Organization	Human	Intestine	A3	2.3e-19
BNIP3L	GOBP_Negative_Regulation_Of_Cell_Death	Human	Intestine	A3	5.8e-14
BNIP3L	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
BNIP3L	GOBP_Positive_Regulation_Of_Catabolic_Process	Human	Intestine	A3	2.8e-16
BNIP3L	GOBP_Positive_Regulation_Of_Cell_Death	Human	Intestine	A3	4.5e-11
BNIP3L	GOBP_Positive_Regulation_Of_Membrane_Permeability	Human	Intestine	A3	4.2e-15
BNIP3L	GOBP_Process_Utilizing_Autophagic_Mechanism	Human	Intestine	A3	4.7e-11
BNIP3L	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
BNIP3L	GOBP_Protein_Localization_To_Mitochondrion	Human	Intestine	A3	3.0e-13
BNIP3L	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
BNIP3L	GOBP_Protein_Targeting	Human	Intestine	A3	6.5e-09
BNIP3L	GOBP_Protein_Targeting_To_Mitochondrion	Human	Intestine	A3	6.4e-07
BNIP3L	GOBP_Regulation_Of_Autophagy	Human	Intestine	A3	1.5e-09
BNIP3L	GOBP_Regulation_Of_Catabolic_Process	Human	Intestine	A3	3.5e-16
BNIP3L	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
BNIP3L	GOBP_Regulation_Of_Cellular_Localization	Human	Intestine	A3	4.5e-11
BNIP3L	GOBP_Regulation_Of_Establishment_Of_Protein_Localization_To_Mitochondrion	Human	Intestine	A3	2.6e-10
BNIP3L	GOBP_Regulation_Of_Intracellular_Protein_Transport	Human	Intestine	A3	2.3e-11
BNIP3L	GOBP_Regulation_Of_Intracellular_Transport	Human	Intestine	A3	4.4e-10
BNIP3L	GOBP_Regulation_Of_Membrane_Permeability	Human	Intestine	A3	6.7e-12
BNIP3L	GOBP_Regulation_Of_Membrane_Potential	Human	Intestine	A3	5.6e-08
BNIP3L	GOBP_Regulation_Of_Mitochondrial_Membrane_Permeability	Human	Intestine	A3	2.1e-12
BNIP3L	GOBP_Regulation_Of_Mitochondrion_Organization	Human	Intestine	A3	1.6e-17
BNIP3L	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
BNIP3L	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
BNIP3L	GOBP_Regulation_Of_Protein_Targeting	Human	Intestine	A3	1.7e-13
BNIP3L	GOBP_Regulation_Of_Transport	Human	Intestine	A3	4.4e-11
BNIP3L	GOBP_Response_To_Abiotic_Stimulus	Human	Intestine	A3	5.3e-18
BNIP3L	GOBP_Response_To_Oxygen_Levels	Human	Intestine	A3	7.3e-15
BNIP3L	GOBP_Response_To_Virus	Human	Intestine	A3	2.4e-11
BNIP3L	GOBP_Autophagy_Of_Mitochondrion	Human	Intestine	A8	8.5e-14
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
BNIP3L	GOBP_Negative_Regulation_Of_Membrane_Potential	Human	Intestine	A8	3.6e-09
BNIP3L	GOBP_Organelle_Disassembly	Human	Intestine	A8	3.1e-16
BNIP3L	GOBP_Regulation_Of_Anion_Transport	Human	Intestine	A8	2.7e-14
BNIP3L	GOBP_Regulation_Of_Autophagy_Of_Mitochondrion	Human	Intestine	A8	1.0e-12
BNIP3L	GOBP_Regulation_Of_Ion_Transport	Human	Intestine	A8	2.0e-13
BNIP3L	GOBP_Regulation_Of_Peptide_Transport	Human	Intestine	A8	1.3e-14
BNIP3L	GOBP_Positive_Regulation_Of_Autophagy	Human	Pancreas	PDAC-B-st1	1.8e-05
BNIP3L	GOBP_Protein_Targeting	Human	Pancreas	PDAC-B-st1	9.4e-05
BNIP3L	GOBP_Regulation_Of_Anion_Transport	Human	Pancreas	PDAC-B-st1	4.7e-06
BNIP3L	GOBP_Regulation_Of_Autophagy_Of_Mitochondrion	Human	Pancreas	PDAC-B-st1	8.8e-05
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
BNIP3L	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
BNIP3L	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
BNIP3L	GOBP_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	1.5e-11
BNIP3L	GOBP_Regulation_Of_Mitochondrial_Membrane_Potential	Human	Uterus	rep_25	9.0e-11
BNIP3L	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
BNIP3L	GOBP_Cellular_Component_Disassembly	Human	Uterus	rep_26	2.7e-06
BNIP3L	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
BNIP3L	GOBP_Macroautophagy	Human	Uterus	rep_26	1.7e-06
BNIP3L	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
BNIP3L	GOBP_Mitochondrial_Membrane_Organization	Human	Uterus	rep_26	1.5e-06
BNIP3L	GOBP_Mitochondrial_Protein_Catabolic_Process	Human	Uterus	rep_26	8.9e-15
BNIP3L	GOBP_Negative_Regulation_Of_Membrane_Potential	Human	Uterus	rep_26	3.6e-09
BNIP3L	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
BNIP3L	GOBP_Positive_Regulation_Of_Membrane_Permeability	Human	Uterus	rep_26	9.7e-06
BNIP3L	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
BNIP3L	GOBP_Regulation_Of_Autophagy	Human	Uterus	rep_26	3.2e-06
BNIP3L	GOBP_Regulation_Of_Establishment_Of_Protein_Localization_To_Mitochondrion	Human	Uterus	rep_26	3.4e-12
BNIP3L	GOBP_Regulation_Of_Macroautophagy	Human	Uterus	rep_26	9.2e-09
BNIP3L	GOBP_Response_To_Virus	Human	Uterus	rep_26	1.3e-09
BNIP3L	GOBP_Regulation_Of_Membrane_Potential	Human	Uterus	rep_29	4.3e-06
BNIP3L	GOBP_Regulation_Of_Peptide_Transport	Human	Uterus	rep_29	1.2e-06
BNIP3L	GOBP_Apoptotic_Mitochondrial_Changes	Human	Breast	rep_1	9.3e-30
BNIP3L	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
BNIP3L	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
BNIP3L	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
BNIP3L	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
BNIP3L	GOBP_Positive_Regulation_Of_Cell_Death	Human	Breast	rep_1	2.2e-15
BNIP3L	GOBP_Regulation_Of_Cellular_Localization	Human	Breast	rep_1	5.5e-07
BNIP3L	GOBP_Regulation_Of_Intracellular_Protein_Transport	Human	Breast	rep_1	2.3e-07
BNIP3L	GOBP_Regulation_Of_Intracellular_Transport	Human	Breast	rep_1	4.7e-13
BNIP3L	GOBP_Regulation_Of_Ion_Transport	Human	Breast	rep_1	1.7e-09
BNIP3L	GOBP_Regulation_Of_Membrane_Potential	Human	Breast	rep_1	5.7e-09
BNIP3L	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
BNIP3L	GOBP_Regulation_Of_Peptide_Transport	Human	Breast	rep_1	7.5e-04
BNIP3L	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
BNIP3L	GOBP_Regulation_Of_Transport	Human	Breast	rep_1	3.7e-17
BNIP3L	GOBP_Response_To_Abiotic_Stimulus	Human	Breast	rep_1	2.6e-19
BNIP3L	GOBP_Response_To_Oxygen_Levels	Human	Breast	rep_1	6.1e-99
BNIP3L	GOBP_Response_To_Virus	Human	Breast	rep_1	7.9e-19
BNIP3L	GOBP_Cellular_Component_Disassembly	Human	Breast	rep_5	2.0e-06
BNIP3L	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
BNIP3L	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Breast	rep_5	4.9e-11
BNIP3L	GOBP_Negative_Regulation_Of_Cell_Death	Human	Breast	rep_5	1.9e-07
BNIP3L	GOBP_Positive_Regulation_Of_Autophagy	Human	Breast	rep_5	1.7e-07
BNIP3L	GOBP_Positive_Regulation_Of_Macroautophagy	Human	Breast	rep_5	5.7e-17
BNIP3L	GOBP_Regulation_Of_Anion_Transport	Human	Breast	rep_5	1.6e-05
BNIP3L	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
BNIP3L	GOBP_Regulation_Of_Mitochondrial_Membrane_Potential	Human	Breast	rep_5	3.6e-04
BNIP3L	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
BNIP3L	GOBP_Autophagy_Of_Mitochondrion	Human	Breast	rep_6	1.7e-09
BNIP3L	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Breast	rep_6	8.5e-11
BNIP3L	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
BNIP3L	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
BNIP3L	GOBP_Macroautophagy	Human	Breast	rep_6	6.1e-10
BNIP3L	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
BNIP3L	GOBP_Mitochondrial_Membrane_Organization	Human	Breast	rep_6	3.7e-05
BNIP3L	GOBP_Mitochondrial_Outer_Membrane_Permeabilization	Human	Breast	rep_6	2.3e-09
BNIP3L	GOBP_Mitochondrial_Transport	Human	Breast	rep_6	6.5e-10
BNIP3L	GOBP_Mitochondrion_Organization	Human	Breast	rep_6	2.0e-05
BNIP3L	GOBP_Negative_Regulation_Of_Membrane_Potential	Human	Breast	rep_6	1.4e-04
BNIP3L	GOBP_Organelle_Disassembly	Human	Breast	rep_6	2.0e-07
BNIP3L	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
BNIP3L	GOBP_Positive_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	9.2e-08
BNIP3L	GOBP_Positive_Regulation_Of_Membrane_Permeability	Human	Breast	rep_6	2.9e-09
BNIP3L	GOBP_Process_Utilizing_Autophagic_Mechanism	Human	Breast	rep_6	1.9e-08
BNIP3L	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
BNIP3L	GOBP_Protein_Localization_To_Mitochondrion	Human	Breast	rep_6	7.1e-06
BNIP3L	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
BNIP3L	GOBP_Protein_Targeting	Human	Breast	rep_6	5.5e-10
BNIP3L	GOBP_Protein_Targeting_To_Mitochondrion	Human	Breast	rep_6	2.4e-13
BNIP3L	GOBP_Regulation_Of_Autophagy	Human	Breast	rep_6	7.8e-04
BNIP3L	GOBP_Regulation_Of_Autophagy_Of_Mitochondrion	Human	Breast	rep_6	7.0e-04
BNIP3L	GOBP_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	3.3e-04
BNIP3L	GOBP_Regulation_Of_Establishment_Of_Protein_Localization_To_Mitochondrion	Human	Breast	rep_6	1.1e-05
BNIP3L	GOBP_Regulation_Of_Macroautophagy	Human	Breast	rep_6	3.2e-07
BNIP3L	GOBP_Regulation_Of_Membrane_Permeability	Human	Breast	rep_6	1.8e-09
BNIP3L	GOBP_Regulation_Of_Mitochondrial_Membrane_Permeability	Human	Breast	rep_6	2.3e-08
BNIP3L	GOBP_Regulation_Of_Mitochondrion_Organization	Human	Breast	rep_6	1.3e-06
BNIP3L	GOBP_Regulation_Of_Protein_Targeting	Human	Breast	rep_6	1.3e-05
BNIP3L	GOBP_Protein_Targeting_To_Mitochondrion	Human	Skin	P5_rep1	1.3e-08
BNIP3L	GOBP_Mitochondrial_Membrane_Organization	Human	Skin	P5_rep3	2.4e-11
BNIP3L	GOBP_Regulation_Of_Membrane_Potential	Human	Skin	P5_rep3	3.6e-10
BNIP3L	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
BNIP3L	GOBP_Mitochondrial_Protein_Catabolic_Process	Human	Skin	P10_rep1	6.0e-16
BNIP3L	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
BNIP3L	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Lung	rep_1	2.8e-10
BNIP3L	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
BNIP3L	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
BNIP3L	GOBP_Cellular_Component_Disassembly	Human	Lung	rep_2	5.6e-07
BNIP3L	GOBP_Positive_Regulation_Of_Cell_Death	Human	Lung	rep_2	3.0e-07
BNIP3L	GOBP_Regulation_Of_Peptide_Transport	Human	Lung	rep_2	2.6e-07

Top

BNIP3L function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

BNIP3L function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for BNIP3L envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for BNIP3L

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for BNIP3L

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source