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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

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Spatial pattern pathway

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Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: ATPAF1 (spascer ID:64756)

Gene summary for ATPAF1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

ATPAF1

Gene ID

64756

Gene nameATP synthase mitochondrial F1 complex assembly factor 1
SynonymsATP11|ATP11p
Cytomap1p33
Type of geneprotein-coding
DescriptionATP synthase mitochondrial F1 complex assembly factor 1homolog of yeast ATP11
Modification date20220513
UniProtAcc

Q5TC12


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
ATPAF1

GO:0005739

mitochondrion

21873635

Component
ATPAF1

GO:0033615

mitochondrial proton-transporting ATP synthase complex assembly

21873635

Process

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Spatial pattern events for ATPAF1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
ATPAF1HumanLiverrep_liver1 344172251.97e-11
ATPAF1HumanLiverrep_liver2 344172256.98e-16
ATPAF1HumanUterusrep_3 348579544.65e-12

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot


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Spatial pattern pathway has ATPAF1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
ATPAF1GOBP_Mitochondrion_OrganizationHumanIntestineA3 2.3e-19
ATPAF1GOBP_Proton_Transporting_Two_Sector_Atpase_Complex_AssemblyHumanIntestineA8 1.1e-08
ATPAF1GOBP_Proton_Transporting_Two_Sector_Atpase_Complex_AssemblyHumanUterusrep_25 1.5e-13
ATPAF1GOBP_Mitochondrion_OrganizationHumanBreastrep_6 2.0e-05
ATPAF1GOBP_Proton_Transporting_Two_Sector_Atpase_Complex_AssemblyHumanSkinP5_rep1 1.4e-12

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ATPAF1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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ATPAF1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for ATPAF1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for ATPAF1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATPAF1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
ATPAF1C0028754Obesity1CTD_human