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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ANAPC1 (spascer ID:64682)

Gene summary for ANAPC1

Gene summary

Gene information
	Species	Human
	Gene symbol	ANAPC1
	Gene ID	64682
	Gene name	anaphase promoting complex subunit 1
	Synonyms	APC1\|MCPR\|TSG24
	Cytomap	2q13
	Type of gene	protein-coding
	Description	anaphase-promoting complex subunit 1anaphase-promoting complex 1 (meiotic checkpoint regulator)cyclosome subunit 1mitotic checkpoint regulatortestis-specific gene 24 protein
	Modification date	20220513
	UniProtAcc	Q9H1A4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ANAPC1	GO:0005680	anaphase-promoting complex	21873635	Component
ANAPC1	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	21873635	Process
ANAPC1	GO:0031145	anaphase-promoting complex-dependent catabolic process	21873635	Process
ANAPC1	GO:0060090	molecular adaptor activity	21873635	Function
ANAPC1	GO:0070979	protein K11-linked ubiquitination	21873635	Process

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Spatial pattern events for ANAPC1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ANAPC1	Human	Intestine	rep_colon1	34417225	3.90e-08
ANAPC1	Human	Intestine	rep_colon4	34417225	1.14e-15
ANAPC1	Human	Liver	rep_liver1	34417225	1.08e-15
ANAPC1	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has ANAPC1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ANAPC1	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
ANAPC1	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
ANAPC1	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
ANAPC1	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
ANAPC1	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
ANAPC1	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
ANAPC1	GOBP_Cell_Division	Human	Intestine	A3	2.7e-10
ANAPC1	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
ANAPC1	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
ANAPC1	GOBP_Chromosome_Segregation	Human	Intestine	A3	4.7e-12
ANAPC1	GOBP_Chromosome_Separation	Human	Intestine	A3	2.3e-07
ANAPC1	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
ANAPC1	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
ANAPC1	GOBP_Mitotic_Nuclear_Division	Human	Intestine	A3	5.1e-12
ANAPC1	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Intestine	A3	6.7e-13
ANAPC1	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Intestine	A3	7.7e-11
ANAPC1	GOBP_Nuclear_Chromosome_Segregation	Human	Intestine	A3	4.3e-09
ANAPC1	GOBP_Organelle_Fission	Human	Intestine	A3	3.4e-16
ANAPC1	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
ANAPC1	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Intestine	A3	4.6e-13
ANAPC1	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
ANAPC1	GOBP_Protein_Polyubiquitination	Human	Intestine	A3	2.1e-10
ANAPC1	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
ANAPC1	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
ANAPC1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
ANAPC1	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
ANAPC1	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
ANAPC1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
ANAPC1	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
ANAPC1	GOBP_Sister_Chromatid_Segregation	Human	Intestine	A3	1.0e-11
ANAPC1	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Intestine	A8	9.8e-07
ANAPC1	GOBP_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Intestine	A8	1.0e-15
ANAPC1	GOBP_Regulation_Of_Chromosome_Segregation	Human	Intestine	A8	4.3e-08
ANAPC1	GOBP_Regulation_Of_Chromosome_Separation	Human	Intestine	A8	1.3e-16
ANAPC1	GOBP_Cell_Division	Human	Pancreas	PDAC-B-st1	5.8e-05
ANAPC1	GOBP_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
ANAPC1	GOBP_Nuclear_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
ANAPC1	GOBP_Organelle_Fission	Human	Pancreas	PDAC-B-st1	3.9e-05
ANAPC1	GOBP_Protein_Polyubiquitination	Human	Uterus	rep_25	1.1e-17
ANAPC1	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
ANAPC1	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
ANAPC1	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
ANAPC1	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
ANAPC1	GOBP_Chromosome_Segregation	Human	Uterus	rep_26	5.6e-19
ANAPC1	GOBP_Chromosome_Separation	Human	Uterus	rep_26	1.2e-11
ANAPC1	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
ANAPC1	GOBP_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Uterus	rep_26	1.9e-09
ANAPC1	GOBP_Mitotic_Nuclear_Division	Human	Uterus	rep_26	2.4e-07
ANAPC1	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Uterus	rep_26	4.0e-12
ANAPC1	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	1.1e-07
ANAPC1	GOBP_Nuclear_Chromosome_Segregation	Human	Uterus	rep_26	1.5e-12
ANAPC1	GOBP_Organelle_Fission	Human	Uterus	rep_26	6.0e-11
ANAPC1	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
ANAPC1	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Uterus	rep_26	2.2e-12
ANAPC1	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
ANAPC1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
ANAPC1	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
ANAPC1	GOBP_Regulation_Of_Chromosome_Segregation	Human	Uterus	rep_26	3.3e-08
ANAPC1	GOBP_Regulation_Of_Chromosome_Separation	Human	Uterus	rep_26	3.6e-11
ANAPC1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
ANAPC1	GOBP_Sister_Chromatid_Segregation	Human	Uterus	rep_26	3.3e-13
ANAPC1	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
ANAPC1	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
ANAPC1	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
ANAPC1	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
ANAPC1	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
ANAPC1	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
ANAPC1	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
ANAPC1	GOBP_Cell_Division	Human	Breast	rep_6	8.2e-07
ANAPC1	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
ANAPC1	GOBP_Chromosome_Segregation	Human	Breast	rep_6	1.9e-05
ANAPC1	GOBP_Chromosome_Separation	Human	Breast	rep_6	4.1e-08
ANAPC1	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
ANAPC1	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
ANAPC1	GOBP_Mitotic_Nuclear_Division	Human	Breast	rep_6	2.5e-08
ANAPC1	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Breast	rep_6	4.0e-04
ANAPC1	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Breast	rep_6	2.2e-09
ANAPC1	GOBP_Nuclear_Chromosome_Segregation	Human	Breast	rep_6	4.6e-06
ANAPC1	GOBP_Organelle_Fission	Human	Breast	rep_6	3.0e-05
ANAPC1	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
ANAPC1	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Breast	rep_6	6.8e-09
ANAPC1	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
ANAPC1	GOBP_Protein_K11_Linked_Ubiquitination	Human	Breast	rep_6	1.6e-06
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
ANAPC1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
ANAPC1	GOBP_Protein_Polyubiquitination	Human	Breast	rep_6	6.3e-04
ANAPC1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
ANAPC1	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
ANAPC1	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
ANAPC1	GOBP_Regulation_Of_Chromosome_Segregation	Human	Breast	rep_6	2.6e-07
ANAPC1	GOBP_Regulation_Of_Chromosome_Separation	Human	Breast	rep_6	3.3e-05
ANAPC1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
ANAPC1	GOBP_Sister_Chromatid_Segregation	Human	Breast	rep_6	5.3e-04
ANAPC1	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Skin	P5_rep1	5.7e-11
ANAPC1	GOBP_Nuclear_Chromosome_Segregation	Human	Skin	P5_rep1	7.9e-09
ANAPC1	GOBP_Organelle_Fission	Human	Skin	P5_rep3	1.0e-09

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ANAPC1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ANAPC1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ANAPC1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ANAPC1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ANAPC1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
ANAPC1	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET