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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: SGK1 (spascer ID:6446)

Gene summary for SGK1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

SGK1

Gene ID

6446

Gene nameserum/glucocorticoid regulated kinase 1
SynonymsSGK
Cytomap6q23.2
Type of geneprotein-coding
Descriptionserine/threonine-protein kinase Sgk1serine/threonine protein kinase SGK
Modification date20220515
UniProtAcc

O00141


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
SGK1

GO:0004674

protein serine/threonine kinase activity

21873635

Function
SGK1

GO:0005634

nucleus

21873635

Component
SGK1

GO:0005737

cytoplasm

21873635

Component
SGK1

GO:0015459

potassium channel regulator activity

21873635

Function
SGK1

GO:0018105

peptidyl-serine phosphorylation

21873635

Process
SGK1

GO:0035556

intracellular signal transduction

21873635

Process
SGK1

GO:0048812

neuron projection morphogenesis

21873635

Process

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Spatial pattern events for SGK1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
SGK1HumanBrainrep_9 335586953.01e-15
SGK1HumanBrainrep_10 335586953.23e-15
SGK1HumanBrainrep_11 335586956.00e-15
SGK1HumanBrainrep_12 335586953.65e-15
SGK1HumanBladderrep_1 343854569.62e-09
SGK1HumanIntestinerep_colon1 344172251.95e-15
SGK1HumanIntestinerep_colon2 344172258.12e-16
SGK1HumanIntestinerep_colon3 344172251.01e-15
SGK1HumanLiverrep_liver1 344172251.08e-15
SGK1HumanLiverrep_liver2 344172256.98e-16
SGK1HumanLiverrep_liver3 344172251.11e-12
SGK1HumanLiverrep_liver4 344172257.71e-16
SGK1HumanIntestineA1 334064092.09e-15
SGK1HumanIntestineA2 334064092.47e-15
SGK1HumanPancreasPDAC-A-st1 319327302.66e-07
SGK1HumanUterusrep_2 348579542.55e-15
SGK1HumanUterusrep_3 348579543.09e-10
SGK1HumanUterusrep_4 348579541.82e-15
SGK1HumanBreast1160920F 344938728.57e-09
SGK1HumanBreastCID4290 344938721.85e-11
SGK1HumanBreastCID4465 344938725.70e-14
SGK1HumanBreastCID44971 344938721.76e-15
SGK1HumanBreastCID4535 344938726.37e-15
SGK1HumanSkinmel1_rep1 301541481.82e-06
SGK1HumanSkinmel2_rep1 301541481.18e-07
SGK1HumanLungrep_2 353550182.37e-14

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_9_H&E
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Brain_rep_10_H&E
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Brain_rep_11_H&E
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Brain_rep_12_H&E
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Bladder_rep_1_H&E
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Intestine_rep_colon1_H&E
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Intestine_rep_colon2_H&E
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Intestine_rep_colon3_H&E
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Liver_rep_liver1_H&E
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Liver_rep_liver2_H&E
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Liver_rep_liver3_H&E
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Liver_rep_liver4_H&E
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Intestine_A1_H&E
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Intestine_A2_H&E
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Uterus_rep_2_H&E
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Uterus_rep_3_H&E
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Uterus_rep_4_H&E
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Breast_1160920F_H&E
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Breast_CID4290_H&E
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Breast_CID4465_H&E
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Breast_CID44971_H&E
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Breast_CID4535_H&E
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Lung_rep_2_H&E
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Spatial pattern pathway has SGK1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
SGK1GOBP_Cell_MigrationHumanBrainrep_1 3.1e-68
SGK1GOBP_LocomotionHumanBrainrep_1 3.1e-68
SGK1GOBP_NeurogenesisHumanBrainrep_1 7.4e-34
SGK1GOBP_Neuron_DevelopmentHumanBrainrep_1 7.4e-34
SGK1GOBP_Neuron_DifferentiationHumanBrainrep_1 7.4e-34
SGK1GOBP_Positive_Regulation_Of_Molecular_FunctionHumanBrainrep_1 8.7e-71
SGK1GOBP_Positive_Regulation_Of_TransportHumanBrainrep_1 3.1e-16
SGK1GOBP_Regulation_Of_Cellular_Component_MovementHumanBrainrep_1 3.1e-68
SGK1GOBP_Regulation_Of_TransportHumanBrainrep_1 3.1e-16
SGK1GOBP_Transmembrane_TransportHumanBrainrep_1 2.8e-23
SGK1GOBP_Cell_GrowthHumanBrainrep_4 1.0e-14
SGK1GOBP_Cell_MorphogenesisHumanBrainrep_4 1.0e-14
SGK1GOBP_GrowthHumanBrainrep_4 1.0e-14
SGK1GOBP_Response_To_Endogenous_StimulusHumanBrainrep_10 2.8e-23
SGK1GOBP_Response_To_HormoneHumanBrainrep_10 2.8e-23
SGK1GOBP_Response_To_LipidHumanBrainrep_10 2.8e-23
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanBrainrep_10 5.3e-26
SGK1GOBP_Response_To_KetoneHumanBrainrep_11 2.5e-12
SGK1GOBP_Gastric_Acid_SecretionHumanBladderrep_2 4.6e-14
SGK1GOBP_Regulation_Of_Blood_PressureHumanBladderrep_2 2.1e-04
SGK1GOBP_Regulation_Of_Gastric_Acid_SecretionHumanBladderrep_2 7.1e-08
SGK1GOBP_Renal_Sodium_Ion_AbsorptionHumanBladderrep_2 2.0e-07
SGK1GOBP_Response_To_CorticosteroidHumanBladderrep_2 3.3e-18
SGK1GOBP_Cell_GrowthHumanLiverrep_1 2.1e-52
SGK1GOBP_Cell_MigrationHumanLiverrep_1 1.9e-71
SGK1GOBP_Cell_MorphogenesisHumanLiverrep_1 2.1e-52
SGK1GOBP_GrowthHumanLiverrep_1 2.1e-52
SGK1GOBP_LocomotionHumanLiverrep_1 1.9e-71
SGK1GOBP_NeurogenesisHumanLiverrep_1 1.0e-70
SGK1GOBP_Neuron_DevelopmentHumanLiverrep_1 1.5e-73
SGK1GOBP_Neuron_DifferentiationHumanLiverrep_1 1.5e-73
SGK1GOBP_Positive_Regulation_Of_Molecular_FunctionHumanLiverrep_1 2.1e-52
SGK1GOBP_Positive_Regulation_Of_TransportHumanLiverrep_1 9.4e-68
SGK1GOBP_Regulation_Of_Cellular_Component_MovementHumanLiverrep_1 1.9e-71
SGK1GOBP_Regulation_Of_TransportHumanLiverrep_1 9.4e-68
SGK1GOBP_Response_To_Endogenous_StimulusHumanLiverrep_1 3.0e-55
SGK1GOBP_Response_To_HormoneHumanLiverrep_1 3.0e-55
SGK1GOBP_Response_To_KetoneHumanLiverrep_1 1.7e-73
SGK1GOBP_Response_To_LipidHumanLiverrep_1 3.0e-55
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanLiverrep_1 1.5e-74
SGK1GOBP_Transmembrane_TransportHumanLiverrep_1 1.0e-70
SGK1GOBP_Cell_GrowthHumanIntestinerep_colon2 1.5e-57
SGK1GOBP_Cell_MorphogenesisHumanIntestinerep_colon2 1.5e-57
SGK1GOBP_GrowthHumanIntestinerep_colon2 1.5e-57
SGK1GOBP_Positive_Regulation_Of_Molecular_FunctionHumanIntestinerep_colon2 2.3e-37
SGK1GOBP_Positive_Regulation_Of_TransportHumanIntestinerep_colon4 1.0e-26
SGK1GOBP_Regulation_Of_TransportHumanIntestinerep_colon4 1.0e-26
SGK1GOBP_Cell_MigrationHumanIntestinerep_liver2 1.0e-64
SGK1GOBP_LocomotionHumanIntestinerep_liver2 1.0e-64
SGK1GOBP_Regulation_Of_Cellular_Component_MovementHumanIntestinerep_liver2 1.0e-64
SGK1GOBP_Response_To_Endogenous_StimulusHumanIntestinerep_liver2 3.7e-39
SGK1GOBP_Response_To_HormoneHumanIntestinerep_liver2 3.7e-39
SGK1GOBP_Response_To_KetoneHumanIntestinerep_liver2 8.9e-16
SGK1GOBP_Response_To_LipidHumanIntestinerep_liver2 3.7e-39
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanIntestinerep_liver2 3.3e-10
SGK1GOBP_BehaviorHumanIntestineA3 1.8e-11
SGK1GOBP_Cation_TransportHumanIntestineA3 1.3e-09
SGK1GOBP_Cell_GrowthHumanIntestineA3 1.3e-16
SGK1GOBP_Cell_MigrationHumanIntestineA3 1.6e-10
SGK1GOBP_Cell_MorphogenesisHumanIntestineA3 9.7e-08
SGK1GOBP_Cell_Part_MorphogenesisHumanIntestineA3 8.9e-08
SGK1GOBP_Cell_Projection_OrganizationHumanIntestineA3 1.1e-09
SGK1GOBP_Cellular_Response_To_Dna_Damage_StimulusHumanIntestineA3 6.6e-16
SGK1GOBP_Cellular_Response_To_Hormone_StimulusHumanIntestineA3 8.7e-19
SGK1GOBP_Cellular_Response_To_LipidHumanIntestineA3 7.7e-08
SGK1GOBP_Cellular_Response_To_Organic_Cyclic_CompoundHumanIntestineA3 2.5e-14
SGK1GOBP_Cellular_Response_To_Steroid_Hormone_StimulusHumanIntestineA3 5.6e-26
SGK1GOBP_CognitionHumanIntestineA3 5.7e-09
SGK1GOBP_GrowthHumanIntestineA3 3.3e-16
SGK1GOBP_LocomotionHumanIntestineA3 1.9e-08
SGK1GOBP_Nervous_System_ProcessHumanIntestineA3 9.7e-07
SGK1GOBP_NeurogenesisHumanIntestineA3 6.4e-14
SGK1GOBP_Neuron_DevelopmentHumanIntestineA3 1.3e-12
SGK1GOBP_Neuron_DifferentiationHumanIntestineA3 1.4e-11
SGK1GOBP_Peptidyl_Amino_Acid_ModificationHumanIntestineA3 2.7e-09
SGK1GOBP_Peptidyl_Serine_ModificationHumanIntestineA3 9.8e-09
SGK1GOBP_Positive_Regulation_Of_Molecular_FunctionHumanIntestineA3 2.1e-13
SGK1GOBP_Positive_Regulation_Of_TransportHumanIntestineA3 9.5e-08
SGK1GOBP_Positive_Regulation_Of_Transporter_ActivityHumanIntestineA3 1.7e-09
SGK1GOBP_Regulation_Of_Cell_DeathHumanIntestineA3 7.1e-10
SGK1GOBP_Regulation_Of_Cellular_Component_MovementHumanIntestineA3 1.1e-09
SGK1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanIntestineA3 3.1e-19
SGK1GOBP_Regulation_Of_GrowthHumanIntestineA3 3.6e-10
SGK1GOBP_Regulation_Of_TransportHumanIntestineA3 4.4e-11
SGK1GOBP_Regulation_Of_Transporter_ActivityHumanIntestineA3 1.4e-08
SGK1GOBP_Response_To_AlcoholHumanIntestineA3 3.7e-08
SGK1GOBP_Response_To_Endogenous_StimulusHumanIntestineA3 5.2e-09
SGK1GOBP_Response_To_LipidHumanIntestineA3 1.7e-09
SGK1GOBP_Response_To_Organic_Cyclic_CompoundHumanIntestineA3 3.2e-15
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanIntestineA3 8.2e-08
SGK1GOBP_Response_To_Steroid_HormoneHumanIntestineA3 2.1e-13
SGK1GOBP_SecretionHumanIntestineA3 1.8e-13
SGK1GOBP_Transmembrane_TransportHumanIntestineA3 1.4e-10
SGK1GOBP_Acid_SecretionHumanIntestineA8 1.6e-15
SGK1GOBP_Cellular_Response_To_Corticosteroid_StimulusHumanIntestineA8 1.6e-19
SGK1GOBP_Cellular_Response_To_Mineralocorticoid_StimulusHumanIntestineA8 4.6e-10
SGK1GOBP_Cellular_Response_To_Oxygen_Containing_CompoundHumanIntestineA8 1.4e-09
SGK1GOBP_DigestionHumanIntestineA8 3.9e-07
SGK1GOBP_Digestive_System_ProcessHumanIntestineA8 3.9e-07
SGK1GOBP_Long_Term_MemoryHumanIntestineA8 3.9e-07
SGK1GOBP_MemoryHumanIntestineA8 1.2e-07
SGK1GOBP_Regulation_Of_Blood_PressureHumanIntestineA8 4.1e-09
SGK1GOBP_Regulation_Of_SecretionHumanIntestineA8 2.2e-15
SGK1GOBP_Renal_AbsorptionHumanIntestineA8 3.0e-14
SGK1GOBP_Renal_System_ProcessHumanIntestineA8 2.2e-22
SGK1GOBP_Response_To_AldosteroneHumanIntestineA8 2.5e-09
SGK1GOBP_Response_To_CorticosteroidHumanIntestineA8 4.4e-19
SGK1GOBP_Response_To_HormoneHumanIntestineA8 2.3e-13
SGK1GOBP_Response_To_KetoneHumanIntestineA8 1.1e-27
SGK1GOBP_Response_To_MineralocorticoidHumanIntestineA8 1.7e-21
SGK1GOBP_Sodium_Ion_TransportHumanIntestineA8 4.4e-15
SGK1GOBP_Cellular_Response_To_Corticosteroid_StimulusHumanPancreasPDAC-B-st1 3.7e-05
SGK1GOBP_Regulation_Of_Digestive_System_ProcessHumanUterusrep_1 5.2e-08
SGK1GOBP_Response_To_AldosteroneHumanUterusrep_1 2.0e-07
SGK1GOBP_Acid_SecretionHumanUterusrep_25 2.6e-11
SGK1GOBP_Cellular_Response_To_AldehydeHumanUterusrep_25 3.5e-09
SGK1GOBP_Renal_Sodium_Ion_AbsorptionHumanUterusrep_25 1.7e-07
SGK1GOBP_Cellular_Response_To_Corticosteroid_StimulusHumanUterusrep_26 5.2e-07
SGK1GOBP_Cellular_Response_To_Dna_Damage_StimulusHumanUterusrep_26 2.4e-07
SGK1GOBP_Cellular_Response_To_Steroid_Hormone_StimulusHumanUterusrep_26 9.7e-06
SGK1GOBP_Circulatory_System_ProcessHumanUterusrep_26 4.6e-06
SGK1GOBP_CognitionHumanUterusrep_26 3.8e-07
SGK1GOBP_DigestionHumanUterusrep_26 2.4e-06
SGK1GOBP_Digestive_System_ProcessHumanUterusrep_26 3.1e-06
SGK1GOBP_Gastric_Acid_SecretionHumanUterusrep_26 7.4e-09
SGK1GOBP_Nervous_System_ProcessHumanUterusrep_26 2.3e-07
SGK1GOBP_Peptidyl_Serine_ModificationHumanUterusrep_26 1.9e-07
SGK1GOBP_Regulation_Of_SecretionHumanUterusrep_26 1.7e-06
SGK1GOBP_Regulation_Of_System_ProcessHumanUterusrep_26 6.6e-10
SGK1GOBP_Renal_System_ProcessHumanUterusrep_29 2.0e-07
SGK1GOBP_Response_To_CorticosteroidHumanUterusrep_29 4.7e-06
SGK1GOBP_Cation_TransportHumanBreastrep_1 8.4e-53
SGK1GOBP_Cell_GrowthHumanBreastrep_1 6.0e-15
SGK1GOBP_Cell_MigrationHumanBreastrep_1 1.5e-45
SGK1GOBP_Cell_MorphogenesisHumanBreastrep_1 5.7e-26
SGK1GOBP_Cell_Part_MorphogenesisHumanBreastrep_1 6.2e-28
SGK1GOBP_Cell_Projection_OrganizationHumanBreastrep_1 1.8e-20
SGK1GOBP_Cellular_Component_MorphogenesisHumanBreastrep_1 2.7e-58
SGK1GOBP_Cellular_Response_To_Corticosteroid_StimulusHumanBreastrep_1 5.0e-06
SGK1GOBP_Cellular_Response_To_KetoneHumanBreastrep_1 8.9e-05
SGK1GOBP_Circulatory_System_ProcessHumanBreastrep_1 2.1e-34
SGK1GOBP_Gastric_Acid_SecretionHumanBreastrep_1 3.8e-05
SGK1GOBP_LocomotionHumanBreastrep_1 4.5e-54
SGK1GOBP_Nervous_System_ProcessHumanBreastrep_1 1.2e-04
SGK1GOBP_NeurogenesisHumanBreastrep_1 8.0e-11
SGK1GOBP_Neuron_DevelopmentHumanBreastrep_1 2.5e-26
SGK1GOBP_Neuron_DifferentiationHumanBreastrep_1 1.1e-16
SGK1GOBP_Positive_Regulation_Of_TransportHumanBreastrep_1 3.1e-10
SGK1GOBP_Positive_Regulation_Of_Transporter_ActivityHumanBreastrep_1 6.4e-06
SGK1GOBP_Regulation_Of_Blood_PressureHumanBreastrep_1 2.3e-60
SGK1GOBP_Regulation_Of_Cellular_Component_MovementHumanBreastrep_1 5.5e-21
SGK1GOBP_Regulation_Of_Gastric_Acid_SecretionHumanBreastrep_1 3.3e-09
SGK1GOBP_Regulation_Of_GrowthHumanBreastrep_1 2.3e-04
SGK1GOBP_Regulation_Of_SecretionHumanBreastrep_1 1.1e-10
SGK1GOBP_Regulation_Of_System_ProcessHumanBreastrep_1 1.0e-09
SGK1GOBP_Regulation_Of_TransportHumanBreastrep_1 3.7e-17
SGK1GOBP_Regulation_Of_Transporter_ActivityHumanBreastrep_1 8.9e-45
SGK1GOBP_Renal_AbsorptionHumanBreastrep_15.8e-120
SGK1GOBP_Response_To_AlcoholHumanBreastrep_1 1.3e-11
SGK1GOBP_Response_To_CorticosteroidHumanBreastrep_1 1.5e-56
SGK1GOBP_SecretionHumanBreastrep_1 9.7e-57
SGK1GOBP_Transmembrane_TransportHumanBreastrep_1 3.2e-56
SGK1GOBP_Renal_System_ProcessHumanBreastrep_2 5.7e-07
SGK1GOBP_BehaviorHumanBreastrep_5 3.9e-08
SGK1GOBP_Cellular_Response_To_Hormone_StimulusHumanBreastrep_5 9.6e-12
SGK1GOBP_Cellular_Response_To_LipidHumanBreastrep_5 3.3e-11
SGK1GOBP_Cellular_Response_To_Mineralocorticoid_StimulusHumanBreastrep_5 2.2e-04
SGK1GOBP_Cellular_Response_To_Organic_Cyclic_CompoundHumanBreastrep_5 5.1e-18
SGK1GOBP_Cellular_Response_To_Oxygen_Containing_CompoundHumanBreastrep_5 4.9e-11
SGK1GOBP_GrowthHumanBreastrep_5 5.4e-12
SGK1GOBP_Peptidyl_Serine_ModificationHumanBreastrep_5 1.3e-04
SGK1GOBP_Positive_Regulation_Of_Molecular_FunctionHumanBreastrep_5 7.4e-10
SGK1GOBP_Regulation_Of_Cell_DeathHumanBreastrep_5 9.8e-08
SGK1GOBP_Regulation_Of_Digestive_System_ProcessHumanBreastrep_5 2.0e-11
SGK1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanBreastrep_5 8.2e-07
SGK1GOBP_Response_To_Endogenous_StimulusHumanBreastrep_5 3.6e-09
SGK1GOBP_Response_To_HormoneHumanBreastrep_5 2.9e-13
SGK1GOBP_Response_To_KetoneHumanBreastrep_5 3.5e-14
SGK1GOBP_Response_To_LipidHumanBreastrep_5 1.6e-10
SGK1GOBP_Response_To_MineralocorticoidHumanBreastrep_5 1.9e-12
SGK1GOBP_Response_To_Organic_Cyclic_CompoundHumanBreastrep_5 7.5e-14
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanBreastrep_5 4.2e-13
SGK1GOBP_Response_To_Steroid_HormoneHumanBreastrep_5 4.5e-13
SGK1GOBP_Acid_SecretionHumanBreastrep_6 1.6e-14
SGK1GOBP_Cellular_Response_To_AlcoholHumanBreastrep_6 2.4e-06
SGK1GOBP_Cellular_Response_To_AldehydeHumanBreastrep_6 9.6e-12
SGK1GOBP_Cellular_Response_To_Dna_Damage_StimulusHumanBreastrep_6 6.0e-06
SGK1GOBP_DigestionHumanBreastrep_6 4.1e-16
SGK1GOBP_Digestive_System_ProcessHumanBreastrep_6 1.4e-11
SGK1GOBP_MemoryHumanBreastrep_6 8.7e-06
SGK1GOBP_Peptidyl_Amino_Acid_ModificationHumanBreastrep_6 3.8e-05
SGK1GOBP_Renal_Sodium_Ion_AbsorptionHumanBreastrep_6 6.1e-04
SGK1GOBP_Renal_Sodium_Ion_TransportHumanBreastrep_6 3.8e-19
SGK1GOBP_Response_To_AldosteroneHumanBreastrep_6 3.0e-07
SGK1GOBP_Sodium_Ion_TransportHumanBreastrep_6 3.3e-11
SGK1GOBP_Gastric_Acid_SecretionHumanSkinP2_rep2 2.8e-09
SGK1GOBP_Renal_Sodium_Ion_TransportHumanSkinP5_rep1 3.1e-12
SGK1GOBP_Regulation_Of_Gastric_Acid_SecretionHumanSkinP5_rep3 3.8e-08
SGK1GOBP_Renal_AbsorptionHumanSkinP9_rep2 4.5e-10
SGK1GOBP_Cell_GrowthHumanSkinP9_rep3 4.1e-08
SGK1GOBP_Renal_Sodium_Ion_AbsorptionHumanSkinP10_rep1 4.5e-16
SGK1GOBP_Sodium_Ion_TransportHumanSkinP10_rep1 2.7e-08
SGK1GOBP_Acid_SecretionHumanSkinP10_rep2 4.9e-09
SGK1GOBP_Cellular_Response_To_Mineralocorticoid_StimulusHumanSkinP10_rep2 1.4e-14
SGK1GOBP_Long_Term_MemoryHumanSkinP10_rep2 1.1e-15
SGK1GOBP_Regulation_Of_Digestive_System_ProcessHumanSkinP10_rep2 2.3e-11
SGK1GOBP_Response_To_AldosteroneHumanSkinP10_rep2 5.0e-14
SGK1GOBP_Positive_Regulation_Of_Transporter_ActivityHumanSkinP10_rep3 5.8e-23
SGK1GOBP_Cellular_Response_To_Corticosteroid_StimulusHumanLungrep_1 8.4e-08
SGK1GOBP_Cellular_Response_To_LipidHumanLungrep_1 1.3e-10
SGK1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanLungrep_1 1.9e-10
SGK1GOBP_Response_To_LipidHumanLungrep_1 1.8e-09
SGK1GOBP_Response_To_Oxygen_Containing_CompoundHumanLungrep_1 7.8e-08
SGK1GOBP_MemoryHumanLungrep_2 3.9e-09
SGK1GOBP_Regulation_Of_SecretionHumanLungrep_2 9.3e-09
SGK1GOBP_Sodium_Ion_TransportHumanLungrep_2 8.4e-07

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SGK1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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SGK1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for SGK1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for SGK1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
SGK1O00141DB03247Flavin mononucleotideSerine/threonine-protein kinase Sgk1 SmallMoleculeDrugapproved|investigational

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Related Diseases for SGK1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
SGK1C0007097Carcinoma1CTD_human
SGK1C0011882Diabetic Neuropathies1CTD_human
SGK1C0023467Leukemia, Myelocytic, Acute1CTD_human
SGK1C0024667Animal Mammary Neoplasms1CTD_human
SGK1C0024668Mammary Neoplasms, Experimental1CTD_human
SGK1C0026998Acute Myeloid Leukemia, M11CTD_human
SGK1C0041696Unipolar Depression1PSYGENET
SGK1C0041948Uremia1CTD_human
SGK1C0205696Anaplastic carcinoma1CTD_human
SGK1C0205697Carcinoma, Spindle-Cell1CTD_human
SGK1C0205698Undifferentiated carcinoma1CTD_human
SGK1C0205699Carcinomatosis1CTD_human
SGK1C0271673Symmetric Diabetic Proximal Motor Neuropathy1CTD_human
SGK1C0271674Asymmetric Diabetic Proximal Motor Neuropathy1CTD_human
SGK1C0271678Diabetic Mononeuropathy1CTD_human
SGK1C0271680Diabetic Polyneuropathies1CTD_human
SGK1C0271685Diabetic Amyotrophy1CTD_human
SGK1C0271686Diabetic Autonomic Neuropathy1CTD_human
SGK1C0393835Diabetic Asymmetric Polyneuropathy1CTD_human
SGK1C0751074Diabetic Neuralgia1CTD_human
SGK1C1257925Mammary Carcinoma, Animal1CTD_human
SGK1C1269683Major Depressive Disorder1PSYGENET
SGK1C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human