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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: SRSF7 (spascer ID:6432)

Gene summary for SRSF7

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

SRSF7

Gene ID

6432

Gene nameserine and arginine rich splicing factor 7
Synonyms9G8|AAG3|SFRS7
Cytomap2p22.1
Type of geneprotein-coding
Descriptionserine/arginine-rich splicing factor 7SR splicing factor 7aging-associated protein 3splicing factor 9G8splicing factor, arginine/serine-rich 7, 35kDa
Modification date20220513
UniProtAcc

Q16629


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
SRSF7

GO:0000398

mRNA splicing, via spliceosome

21873635

Process
SRSF7

GO:0003723

RNA binding

21873635

Function
SRSF7

GO:0016607

nuclear speck

21873635

Component

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Spatial pattern events for SRSF7

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
SRSF7HumanProstaterep_7 299258781.78e-06
SRSF7HumanBladderrep_2 343854562.17e-14
SRSF7HumanIntestinerep_colon1 344172251.95e-15
SRSF7HumanIntestinerep_colon2 344172258.12e-16
SRSF7HumanIntestinerep_colon3 344172251.89e-08
SRSF7HumanIntestinerep_colon4 344172251.14e-15
SRSF7HumanLiverrep_liver1 344172251.08e-15
SRSF7HumanLiverrep_liver2 344172256.98e-16
SRSF7HumanLiverrep_liver4 344172257.71e-16
SRSF7HumanIntestineA1 334064096.31e-15
SRSF7HumanIntestineA2 334064095.03e-13
SRSF7HumanUterusrep_1 348579547.97e-08
SRSF7HumanUterusrep_3 348579541.66e-15
SRSF7HumanBreast1142243F 344938722.30e-15
SRSF7HumanBreast1160920F 344938728.89e-07
SRSF7HumanBreastCID4465 344938724.08e-08
SRSF7HumanBreastCID44971 344938721.76e-15
SRSF7HumanLungrep_1 353550181.37e-14

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Bladder_rep_2_H&E
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Intestine_rep_colon1_H&E
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Intestine_rep_colon2_H&E
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Intestine_rep_colon3_H&E
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Intestine_rep_colon4_H&E
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Liver_rep_liver1_H&E
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Liver_rep_liver2_H&E
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Liver_rep_liver4_H&E
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Intestine_A1_H&E
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Intestine_A2_H&E
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Uterus_rep_1_H&E
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Uterus_rep_3_H&E
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Breast_1142243F_H&E
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Breast_1160920F_H&E
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Breast_CID4465_H&E
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Breast_CID44971_H&E
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Lung_rep_1_H&E
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Spatial pattern pathway has SRSF7 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
SRSF7GOBP_Cellular_Macromolecule_LocalizationHumanIntestineA3 1.7e-09
SRSF7GOBP_Establishment_Of_Protein_LocalizationHumanIntestineA3 5.0e-10
SRSF7GOBP_Establishment_Of_Rna_LocalizationHumanIntestineA3 9.7e-11
SRSF7GOBP_Intracellular_Protein_TransportHumanIntestineA3 4.8e-12
SRSF7GOBP_Intracellular_TransportHumanIntestineA3 7.6e-15
SRSF7GOBP_Mrna_3_End_ProcessingHumanIntestineA3 4.9e-12
SRSF7GOBP_Mrna_Export_From_NucleusHumanIntestineA3 9.9e-15
SRSF7GOBP_Mrna_Metabolic_ProcessHumanIntestineA3 7.7e-20
SRSF7GOBP_Mrna_ProcessingHumanIntestineA3 4.9e-17
SRSF7GOBP_Mrna_TransportHumanIntestineA3 6.6e-09
SRSF7GOBP_Negative_Regulation_Of_Gene_ExpressionHumanIntestineA3 2.8e-18
SRSF7GOBP_Negative_Regulation_Of_Mrna_Metabolic_ProcessHumanIntestineA3 6.1e-07
SRSF7GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanIntestineA3 7.7e-14
SRSF7GOBP_Nuclear_ExportHumanIntestineA3 3.6e-07
SRSF7GOBP_Nuclear_TransportHumanIntestineA3 5.6e-10
SRSF7GOBP_Nucleobase_Containing_Compound_TransportHumanIntestineA3 2.5e-11
SRSF7GOBP_Protein_Containing_Complex_LocalizationHumanIntestineA3 6.4e-12
SRSF7GOBP_Regulation_Of_Mrna_Metabolic_ProcessHumanIntestineA3 1.6e-13
SRSF7GOBP_Regulation_Of_Mrna_ProcessingHumanIntestineA3 1.2e-11
SRSF7GOBP_Regulation_Of_Rna_SplicingHumanIntestineA3 5.6e-22
SRSF7GOBP_Rna_3_End_ProcessingHumanIntestineA3 9.2e-07
SRSF7GOBP_Rna_Export_From_NucleusHumanIntestineA3 3.3e-10
SRSF7GOBP_Rna_LocalizationHumanIntestineA3 1.4e-08
SRSF7GOBP_Rna_ProcessingHumanIntestineA3 3.9e-09
SRSF7GOBP_Rna_SplicingHumanIntestineA3 3.3e-19
SRSF7GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanIntestineA3 2.2e-12
SRSF7GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_SpliceosomeHumanIntestineA8 1.3e-09
SRSF7GOBP_Response_To_CytokineHumanIntestineA8 1.6e-08
SRSF7GOBP_Response_To_Leukemia_Inhibitory_FactorHumanIntestineA8 1.9e-11
SRSF7GOBP_Mrna_Metabolic_ProcessHumanPancreasPDAC-B-st1 2.6e-05
SRSF7GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_SpliceosomeHumanPancreasPDAC-B-st1 3.6e-05
SRSF7GOBP_Regulation_Of_Rna_SplicingHumanPancreasPDAC-B-st1 3.5e-05
SRSF7GOBP_Rna_Export_From_NucleusHumanPancreasPDAC-B-st1 6.7e-05
SRSF7GOBP_Rna_SplicingHumanPancreasPDAC-B-st1 1.9e-05
SRSF7GOBP_Mrna_Export_From_NucleusHumanPancreasPDAC-A-st2 3.9e-08
SRSF7GOBP_Nuclear_ExportHumanUterusrep_25 7.4e-11
SRSF7GOBP_Nuclear_TransportHumanUterusrep_25 2.3e-13
SRSF7GOBP_Establishment_Of_Rna_LocalizationHumanUterusrep_26 8.7e-07
SRSF7GOBP_Mrna_Export_From_NucleusHumanUterusrep_26 3.9e-08
SRSF7GOBP_Negative_Regulation_Of_Mrna_Metabolic_ProcessHumanUterusrep_26 8.9e-09
SRSF7GOBP_Negative_Regulation_Of_Mrna_ProcessingHumanUterusrep_26 1.2e-06
SRSF7GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_SpliceosomeHumanUterusrep_26 1.6e-12
SRSF7GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanUterusrep_26 2.1e-06
SRSF7GOBP_Negative_Regulation_Of_Rna_SplicingHumanUterusrep_26 1.5e-08
SRSF7GOBP_Response_To_Leukemia_Inhibitory_FactorHumanUterusrep_26 4.5e-06
SRSF7GOBP_Rna_Export_From_NucleusHumanUterusrep_26 3.8e-10
SRSF7GOBP_Rna_LocalizationHumanUterusrep_26 1.2e-09
SRSF7GOBP_Rna_SplicingHumanUterusrep_26 1.0e-05
SRSF7GOBP_Mrna_3_End_ProcessingHumanUterusrep_27 5.1e-08
SRSF7GOBP_Cellular_Macromolecule_LocalizationHumanBreastrep_1 3.7e-09
SRSF7GOBP_Establishment_Of_Protein_LocalizationHumanBreastrep_1 7.2e-05
SRSF7GOBP_Response_To_CytokineHumanBreastrep_1 2.5e-24
SRSF7GOBP_Negative_Regulation_Of_Gene_ExpressionHumanBreastrep_5 5.3e-06
SRSF7GOBP_Intracellular_Protein_TransportHumanBreastrep_6 6.4e-12
SRSF7GOBP_Intracellular_TransportHumanBreastrep_6 1.3e-08
SRSF7GOBP_Mrna_3_End_ProcessingHumanBreastrep_6 6.6e-04
SRSF7GOBP_Mrna_Export_From_NucleusHumanBreastrep_6 1.1e-04
SRSF7GOBP_Mrna_Metabolic_ProcessHumanBreastrep_6 3.0e-08
SRSF7GOBP_Mrna_ProcessingHumanBreastrep_6 1.5e-06
SRSF7GOBP_Mrna_TransportHumanBreastrep_6 1.9e-10
SRSF7GOBP_Negative_Regulation_Of_Mrna_Metabolic_ProcessHumanBreastrep_6 3.0e-04
SRSF7GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_SpliceosomeHumanBreastrep_6 1.1e-04
SRSF7GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanBreastrep_6 3.5e-08
SRSF7GOBP_Nuclear_ExportHumanBreastrep_6 1.4e-05
SRSF7GOBP_Nuclear_TransportHumanBreastrep_6 3.1e-08
SRSF7GOBP_Protein_Containing_Complex_LocalizationHumanBreastrep_6 1.3e-06
SRSF7GOBP_Regulation_Of_Mrna_Metabolic_ProcessHumanBreastrep_6 9.5e-05
SRSF7GOBP_Regulation_Of_Mrna_ProcessingHumanBreastrep_6 2.4e-04
SRSF7GOBP_Regulation_Of_Mrna_Splicing_Via_SpliceosomeHumanBreastrep_6 3.0e-05
SRSF7GOBP_Regulation_Of_Rna_SplicingHumanBreastrep_6 5.8e-06
SRSF7GOBP_Response_To_Leukemia_Inhibitory_FactorHumanBreastrep_6 4.6e-06
SRSF7GOBP_Rna_3_End_ProcessingHumanBreastrep_6 1.8e-05
SRSF7GOBP_Rna_Export_From_NucleusHumanBreastrep_6 9.6e-09
SRSF7GOBP_Rna_LocalizationHumanBreastrep_6 7.7e-05
SRSF7GOBP_Rna_ProcessingHumanBreastrep_6 3.5e-06
SRSF7GOBP_Rna_SplicingHumanBreastrep_6 1.1e-09
SRSF7GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanBreastrep_6 5.4e-08
SRSF7GOBP_Nuclear_TransportHumanSkinP5_rep1 5.0e-19
SRSF7GOBP_Mrna_Metabolic_ProcessHumanSkinP5_rep3 1.8e-08
SRSF7GOBP_Mrna_ProcessingHumanSkinP5_rep3 9.7e-09
SRSF7GOBP_Regulation_Of_Mrna_Metabolic_ProcessHumanSkinP5_rep3 4.0e-08

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SRSF7 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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SRSF7 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for SRSF7 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for SRSF7

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SRSF7

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource