Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SRSF5 (spascer ID:6430)

Gene summary for SRSF5

Gene summary

Gene information
	Species	Human
	Gene symbol	SRSF5
	Gene ID	6430
	Gene name	serine and arginine rich splicing factor 5
	Synonyms	HRS\|SFRS5\|SRP40
	Cytomap	14q24.1
	Type of gene	protein-coding
	Description	serine/arginine-rich splicing factor 5SR splicing factor 5delayed-early protein HRSpre-mRNA-splicing factor SRP40splicing factor, arginine/serine-rich 5
	Modification date	20220513
	UniProtAcc	Q13243

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SRSF5	GO:0000398	mRNA splicing, via spliceosome	21873635	Process
SRSF5	GO:0003723	RNA binding	21873635	Function
SRSF5	GO:0003729	mRNA binding	21873635	Function
SRSF5	GO:0016607	nuclear speck	21873635	Component

Top

Spatial pattern events for SRSF5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SRSF5	Human	Prostate	rep_6	29925878	4.04e-06
SRSF5	Human	Prostate	rep_7	29925878	3.90e-13
SRSF5	Human	Bladder	rep_2	34385456	6.29e-15
SRSF5	Human	Intestine	rep_colon1	34417225	1.95e-15
SRSF5	Human	Intestine	rep_colon2	34417225	8.12e-16
SRSF5	Human	Intestine	rep_colon4	34417225	1.14e-15
SRSF5	Human	Liver	rep_liver1	34417225	1.08e-15
SRSF5	Human	Liver	rep_liver2	34417225	6.98e-16
SRSF5	Human	Intestine	A1	33406409	2.09e-15
SRSF5	Human	Intestine	A2	33406409	2.47e-15
SRSF5	Human	Intestine	A4	33406409	9.63e-15
SRSF5	Human	Uterus	rep_2	34857954	2.55e-15
SRSF5	Human	Uterus	rep_3	34857954	1.66e-15
SRSF5	Human	Breast	1160920F	34493872	1.48e-15
SRSF5	Human	Breast	CID4290	34493872	1.53e-14
SRSF5	Human	Breast	CID44971	34493872	1.76e-15
SRSF5	Human	Skin	P5_rep1	32946785	4.80e-10
SRSF5	Human	Skin	P5_rep2	32946785	2.38e-12
SRSF5	Human	Skin	P10_rep3	32946785	1.89e-06
SRSF5	Human	Skin	mel1_rep2	30154148	5.85e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID44971_H&E
Skin_P5_rep1_H&E
Skin_P5_rep2_H&E
Skin_P10_rep3_H&E

Top

Spatial pattern pathway has SRSF5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SRSF5	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
SRSF5	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
SRSF5	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
SRSF5	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
SRSF5	GOBP_Response_To_Peptide_Hormone	Human	Bladder	rep_2	2.9e-13
SRSF5	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
SRSF5	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
SRSF5	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
SRSF5	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
SRSF5	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
SRSF5	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
SRSF5	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
SRSF5	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SRSF5	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Intestine	A3	8.7e-19
SRSF5	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Intestine	A3	4.8e-16
SRSF5	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Intestine	A3	4.0e-16
SRSF5	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SRSF5	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
SRSF5	GOBP_Gland_Development	Human	Intestine	A3	2.3e-14
SRSF5	GOBP_Hepaticobiliary_System_Development	Human	Intestine	A3	1.6e-07
SRSF5	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SRSF5	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SRSF5	GOBP_Mrna_3_End_Processing	Human	Intestine	A3	4.9e-12
SRSF5	GOBP_Mrna_Export_From_Nucleus	Human	Intestine	A3	9.9e-15
SRSF5	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
SRSF5	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
SRSF5	GOBP_Mrna_Splice_Site_Selection	Human	Intestine	A3	6.7e-13
SRSF5	GOBP_Mrna_Transport	Human	Intestine	A3	6.6e-09
SRSF5	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
SRSF5	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
SRSF5	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
SRSF5	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
SRSF5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
SRSF5	GOBP_Positive_Regulation_Of_Rna_Splicing	Human	Intestine	A3	8.2e-27
SRSF5	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
SRSF5	GOBP_Regeneration	Human	Intestine	A3	5.3e-11
SRSF5	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
SRSF5	GOBP_Regulation_Of_Rna_Splicing	Human	Intestine	A3	5.6e-22
SRSF5	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
SRSF5	GOBP_Response_To_Insulin	Human	Intestine	A3	2.2e-15
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
SRSF5	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Intestine	A3	1.6e-07
SRSF5	GOBP_Rna_3_End_Processing	Human	Intestine	A3	9.2e-07
SRSF5	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
SRSF5	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
SRSF5	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
SRSF5	GOBP_Rna_Splicing	Human	Intestine	A3	3.3e-19
SRSF5	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Intestine	A3	2.2e-12
SRSF5	GOBP_Spliceosomal_Complex_Assembly	Human	Intestine	A3	8.7e-10
SRSF5	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
SRSF5	GOBP_Cellular_Response_To_Peptide	Human	Intestine	A8	2.9e-08
SRSF5	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
SRSF5	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
SRSF5	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
SRSF5	GOBP_Response_To_Peptide_Hormone	Human	Intestine	A8	3.4e-09
SRSF5	GOBP_Animal_Organ_Regeneration	Human	Pancreas	PDAC-B-st1	2.9e-05
SRSF5	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
SRSF5	GOBP_Regeneration	Human	Pancreas	PDAC-B-st1	6.7e-06
SRSF5	GOBP_Regulation_Of_Rna_Splicing	Human	Pancreas	PDAC-B-st1	3.5e-05
SRSF5	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
SRSF5	GOBP_Rna_Splicing	Human	Pancreas	PDAC-B-st1	1.9e-05
SRSF5	GOBP_Mrna_Export_From_Nucleus	Human	Pancreas	PDAC-A-st2	3.9e-08
SRSF5	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
SRSF5	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
SRSF5	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
SRSF5	GOBP_Gland_Development	Human	Uterus	rep_26	1.6e-07
SRSF5	GOBP_Mrna_Export_From_Nucleus	Human	Uterus	rep_26	3.9e-08
SRSF5	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Uterus	rep_26	4.6e-06
SRSF5	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
SRSF5	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
SRSF5	GOBP_Rna_Splicing	Human	Uterus	rep_26	1.0e-05
SRSF5	GOBP_Spliceosomal_Complex_Assembly	Human	Uterus	rep_26	5.6e-09
SRSF5	GOBP_Mrna_3_End_Processing	Human	Uterus	rep_27	5.1e-08
SRSF5	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SRSF5	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SRSF5	GOBP_Gland_Development	Human	Breast	rep_1	2.0e-26
SRSF5	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
SRSF5	GOBP_Regeneration	Human	Breast	rep_1	2.9e-06
SRSF5	GOBP_Response_To_Insulin	Human	Breast	rep_1	5.1e-04
SRSF5	GOBP_Response_To_Peptide_Hormone	Human	Breast	rep_1	2.0e-36
SRSF5	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Breast	rep_5	9.6e-12
SRSF5	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Breast	rep_5	2.2e-04
SRSF5	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
SRSF5	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
SRSF5	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Breast	rep_5	6.3e-04
SRSF5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
SRSF5	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
SRSF5	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
SRSF5	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
SRSF5	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
SRSF5	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
SRSF5	GOBP_Animal_Organ_Regeneration	Human	Breast	rep_6	1.9e-10
SRSF5	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
SRSF5	GOBP_Cellular_Response_To_Peptide	Human	Breast	rep_6	8.4e-11
SRSF5	GOBP_Hepaticobiliary_System_Development	Human	Breast	rep_6	1.5e-07
SRSF5	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SRSF5	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SRSF5	GOBP_Liver_Regeneration	Human	Breast	rep_6	9.3e-15
SRSF5	GOBP_Mrna_3_End_Processing	Human	Breast	rep_6	6.6e-04
SRSF5	GOBP_Mrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
SRSF5	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
SRSF5	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
SRSF5	GOBP_Mrna_Splice_Site_Selection	Human	Breast	rep_6	7.1e-06
SRSF5	GOBP_Mrna_Transport	Human	Breast	rep_6	1.9e-10
SRSF5	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
SRSF5	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
SRSF5	GOBP_Positive_Regulation_Of_Rna_Splicing	Human	Breast	rep_6	2.1e-04
SRSF5	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
SRSF5	GOBP_Regulation_Of_Rna_Splicing	Human	Breast	rep_6	5.8e-06
SRSF5	GOBP_Ribonucleoprotein_Complex_Biogenesis	Human	Breast	rep_6	1.3e-07
SRSF5	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Breast	rep_6	1.4e-08
SRSF5	GOBP_Rna_3_End_Processing	Human	Breast	rep_6	1.8e-05
SRSF5	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
SRSF5	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
SRSF5	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
SRSF5	GOBP_Rna_Splicing	Human	Breast	rep_6	1.1e-09
SRSF5	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Breast	rep_6	5.4e-08
SRSF5	GOBP_Spliceosomal_Complex_Assembly	Human	Breast	rep_6	2.2e-12
SRSF5	GOBP_Regeneration	Human	Skin	P2_rep2	5.2e-08
SRSF5	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
SRSF5	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
SRSF5	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
SRSF5	GOBP_Mrna_Splice_Site_Selection	Human	Skin	P10_rep2	2.9e-12
SRSF5	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08

Top

SRSF5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

SRSF5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for SRSF5 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for SRSF5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SRSF5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SRSF5	C0023895	Liver diseases	1	CTD_human
SRSF5	C0086565	Liver Dysfunction	1	CTD_human
SRSF5	C0149504	Encephalopathy, Toxic	1	CTD_human
SRSF5	C0154659	Toxic Encephalitis	1	CTD_human
SRSF5	C0235032	Neurotoxicity Syndromes	1	CTD_human