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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SRSF4 (spascer ID:6429)

Gene summary for SRSF4

Gene summary

Gene information
	Species	Human
	Gene symbol	SRSF4
	Gene ID	6429
	Gene name	serine and arginine rich splicing factor 4
	Synonyms	SFRS4\|SRP75
	Cytomap	1p35.3
	Type of gene	protein-coding
	Description	serine/arginine-rich splicing factor 4SR splicing factor 4SRP001LBpre-mRNA-splicing factor SRP75splicing factor, arginine/serine-rich 4
	Modification date	20220513
	UniProtAcc	Q08170

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SRSF4	GO:0000398	mRNA splicing, via spliceosome	21873635	Process
SRSF4	GO:0003723	RNA binding	21873635	Function
SRSF4	GO:0003729	mRNA binding	21873635	Function
SRSF4	GO:0016607	nuclear speck	21873635	Component

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Spatial pattern events for SRSF4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SRSF4	Human	Bladder	rep_2	34385456	1.03e-06
SRSF4	Human	Liver	rep_liver2	34417225	8.80e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_2_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has SRSF4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SRSF4	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
SRSF4	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
SRSF4	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
SRSF4	GOBP_Response_To_Peptide_Hormone	Human	Bladder	rep_2	2.9e-13
SRSF4	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
SRSF4	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
SRSF4	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
SRSF4	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
SRSF4	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SRSF4	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SRSF4	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
SRSF4	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SRSF4	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SRSF4	GOBP_Mrna_3_End_Processing	Human	Intestine	A3	4.9e-12
SRSF4	GOBP_Mrna_Export_From_Nucleus	Human	Intestine	A3	9.9e-15
SRSF4	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
SRSF4	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
SRSF4	GOBP_Mrna_Transport	Human	Intestine	A3	6.6e-09
SRSF4	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Metabolic_Process	Human	Intestine	A3	6.1e-07
SRSF4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
SRSF4	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
SRSF4	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
SRSF4	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
SRSF4	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
SRSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Intestine	A3	1.6e-13
SRSF4	GOBP_Regulation_Of_Mrna_Processing	Human	Intestine	A3	1.2e-11
SRSF4	GOBP_Regulation_Of_Rna_Splicing	Human	Intestine	A3	5.6e-22
SRSF4	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
SRSF4	GOBP_Response_To_Insulin	Human	Intestine	A3	2.2e-15
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
SRSF4	GOBP_Rna_3_End_Processing	Human	Intestine	A3	9.2e-07
SRSF4	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
SRSF4	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
SRSF4	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
SRSF4	GOBP_Rna_Splicing	Human	Intestine	A3	3.3e-19
SRSF4	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Intestine	A3	2.2e-12
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Intestine	A8	1.3e-09
SRSF4	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
SRSF4	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
SRSF4	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
SRSF4	GOBP_Response_To_Peptide_Hormone	Human	Intestine	A8	3.4e-09
SRSF4	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Pancreas	PDAC-B-st1	3.6e-05
SRSF4	GOBP_Regulation_Of_Rna_Splicing	Human	Pancreas	PDAC-B-st1	3.5e-05
SRSF4	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
SRSF4	GOBP_Rna_Splicing	Human	Pancreas	PDAC-B-st1	1.9e-05
SRSF4	GOBP_Mrna_Export_From_Nucleus	Human	Pancreas	PDAC-A-st2	3.9e-08
SRSF4	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
SRSF4	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
SRSF4	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
SRSF4	GOBP_Mrna_Export_From_Nucleus	Human	Uterus	rep_26	3.9e-08
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Metabolic_Process	Human	Uterus	rep_26	8.9e-09
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Processing	Human	Uterus	rep_26	1.2e-06
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Uterus	rep_26	1.6e-12
SRSF4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
SRSF4	GOBP_Negative_Regulation_Of_Rna_Splicing	Human	Uterus	rep_26	1.5e-08
SRSF4	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
SRSF4	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
SRSF4	GOBP_Rna_Splicing	Human	Uterus	rep_26	1.0e-05
SRSF4	GOBP_Mrna_3_End_Processing	Human	Uterus	rep_27	5.1e-08
SRSF4	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SRSF4	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SRSF4	GOBP_Response_To_Insulin	Human	Breast	rep_1	5.1e-04
SRSF4	GOBP_Response_To_Peptide_Hormone	Human	Breast	rep_1	2.0e-36
SRSF4	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
SRSF4	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
SRSF4	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
SRSF4	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
SRSF4	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
SRSF4	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SRSF4	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SRSF4	GOBP_Mrna_3_End_Processing	Human	Breast	rep_6	6.6e-04
SRSF4	GOBP_Mrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
SRSF4	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
SRSF4	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
SRSF4	GOBP_Mrna_Transport	Human	Breast	rep_6	1.9e-10
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-04
SRSF4	GOBP_Negative_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Breast	rep_6	1.1e-04
SRSF4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
SRSF4	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
SRSF4	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
SRSF4	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
SRSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Breast	rep_6	9.5e-05
SRSF4	GOBP_Regulation_Of_Mrna_Processing	Human	Breast	rep_6	2.4e-04
SRSF4	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Breast	rep_6	3.0e-05
SRSF4	GOBP_Regulation_Of_Rna_Splicing	Human	Breast	rep_6	5.8e-06
SRSF4	GOBP_Rna_3_End_Processing	Human	Breast	rep_6	1.8e-05
SRSF4	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
SRSF4	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
SRSF4	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
SRSF4	GOBP_Rna_Splicing	Human	Breast	rep_6	1.1e-09
SRSF4	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Breast	rep_6	5.4e-08
SRSF4	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
SRSF4	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
SRSF4	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
SRSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Skin	P5_rep3	4.0e-08
SRSF4	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08

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SRSF4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SRSF4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SRSF4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SRSF4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SRSF4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source