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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SRSF3 (spascer ID:6428)

Gene summary for SRSF3

Gene summary

Gene information
	Species	Human
	Gene symbol	SRSF3
	Gene ID	6428
	Gene name	serine and arginine rich splicing factor 3
	Synonyms	SFRS3\|SRp20
	Cytomap	6p21.31-p21.2
	Type of gene	protein-coding
	Description	serine/arginine-rich splicing factor 3epididymis secretory sperm binding proteinpre-mRNA splicing factor SRp20pre-mRNA-splicing factor SRP20splicing factor, arginine/serine-rich 3splicing factor, arginine/serine-rich, 20-kD
	Modification date	20220513
	UniProtAcc	P84103

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SRSF3	GO:0000398	mRNA splicing, via spliceosome	21873635	Process
SRSF3	GO:0003723	RNA binding	21873635	Function
SRSF3	GO:0016607	nuclear speck	21873635	Component

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Spatial pattern events for SRSF3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SRSF3	Human	Brain	rep_10	33558695	1.93e-07
SRSF3	Human	Prostate	rep_1	29925878	3.85e-06
SRSF3	Human	Prostate	rep_7	29925878	7.08e-07
SRSF3	Human	Bladder	rep_2	34385456	6.29e-15
SRSF3	Human	Intestine	rep_colon1	34417225	1.95e-15
SRSF3	Human	Intestine	rep_colon2	34417225	8.12e-16
SRSF3	Human	Intestine	rep_colon3	34417225	5.45e-11
SRSF3	Human	Intestine	rep_colon4	34417225	1.14e-15
SRSF3	Human	Liver	rep_liver1	34417225	1.08e-15
SRSF3	Human	Liver	rep_liver2	34417225	6.98e-16
SRSF3	Human	Liver	rep_liver4	34417225	7.71e-16
SRSF3	Human	Intestine	A1	33406409	6.31e-15
SRSF3	Human	Intestine	A2	33406409	3.85e-15
SRSF3	Human	Uterus	rep_1	34857954	5.13e-15
SRSF3	Human	Uterus	rep_3	34857954	1.66e-15
SRSF3	Human	Uterus	rep_4	34857954	6.86e-13
SRSF3	Human	Breast	1142243F	34493872	1.01e-13
SRSF3	Human	Breast	1160920F	34493872	1.28e-10
SRSF3	Human	Breast	CID4290	34493872	3.38e-12
SRSF3	Human	Breast	CID4465	34493872	3.05e-06
SRSF3	Human	Breast	CID44971	34493872	1.76e-15
SRSF3	Human	Lung	rep_1	35355018	7.55e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_10_H&E
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has SRSF3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SRSF3	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SRSF3	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SRSF3	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
SRSF3	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SRSF3	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SRSF3	GOBP_Mrna_3_End_Processing	Human	Intestine	A3	4.9e-12
SRSF3	GOBP_Mrna_Export_From_Nucleus	Human	Intestine	A3	9.9e-15
SRSF3	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
SRSF3	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
SRSF3	GOBP_Mrna_Transport	Human	Intestine	A3	6.6e-09
SRSF3	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
SRSF3	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
SRSF3	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
SRSF3	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
SRSF3	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Intestine	A3	1.6e-13
SRSF3	GOBP_Regulation_Of_Mrna_Processing	Human	Intestine	A3	1.2e-11
SRSF3	GOBP_Regulation_Of_Rna_Splicing	Human	Intestine	A3	5.6e-22
SRSF3	GOBP_Rna_3_End_Processing	Human	Intestine	A3	9.2e-07
SRSF3	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
SRSF3	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
SRSF3	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
SRSF3	GOBP_Rna_Splicing	Human	Intestine	A3	3.3e-19
SRSF3	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Intestine	A3	2.2e-12
SRSF3	GOBP_Response_To_Cytokine	Human	Intestine	A8	1.6e-08
SRSF3	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Intestine	A8	1.9e-11
SRSF3	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
SRSF3	GOBP_Regulation_Of_Rna_Splicing	Human	Pancreas	PDAC-B-st1	3.5e-05
SRSF3	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
SRSF3	GOBP_Rna_Splicing	Human	Pancreas	PDAC-B-st1	1.9e-05
SRSF3	GOBP_Mrna_Export_From_Nucleus	Human	Pancreas	PDAC-A-st2	3.9e-08
SRSF3	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
SRSF3	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
SRSF3	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
SRSF3	GOBP_Mrna_Export_From_Nucleus	Human	Uterus	rep_26	3.9e-08
SRSF3	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Uterus	rep_26	4.5e-06
SRSF3	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
SRSF3	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
SRSF3	GOBP_Rna_Splicing	Human	Uterus	rep_26	1.0e-05
SRSF3	GOBP_Mrna_3_End_Processing	Human	Uterus	rep_27	5.1e-08
SRSF3	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SRSF3	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SRSF3	GOBP_Response_To_Cytokine	Human	Breast	rep_1	2.5e-24
SRSF3	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SRSF3	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SRSF3	GOBP_Mrna_3_End_Processing	Human	Breast	rep_6	6.6e-04
SRSF3	GOBP_Mrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
SRSF3	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
SRSF3	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
SRSF3	GOBP_Mrna_Transport	Human	Breast	rep_6	1.9e-10
SRSF3	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
SRSF3	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
SRSF3	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
SRSF3	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Breast	rep_6	9.5e-05
SRSF3	GOBP_Regulation_Of_Mrna_Processing	Human	Breast	rep_6	2.4e-04
SRSF3	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Human	Breast	rep_6	3.0e-05
SRSF3	GOBP_Regulation_Of_Rna_Splicing	Human	Breast	rep_6	5.8e-06
SRSF3	GOBP_Response_To_Leukemia_Inhibitory_Factor	Human	Breast	rep_6	4.6e-06
SRSF3	GOBP_Rna_3_End_Processing	Human	Breast	rep_6	1.8e-05
SRSF3	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
SRSF3	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
SRSF3	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
SRSF3	GOBP_Rna_Splicing	Human	Breast	rep_6	1.1e-09
SRSF3	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Breast	rep_6	5.4e-08
SRSF3	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
SRSF3	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
SRSF3	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
SRSF3	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Skin	P5_rep3	4.0e-08

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SRSF3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SRSF3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SRSF3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SRSF3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SRSF3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SRSF3	C0005586	Bipolar Disorder	1	PSYGENET