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Spatial pattern gene: SRSF2 (spascer ID:6427) |
Gene summary for SRSF2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SRSF2 | Gene ID | 6427 |
| Gene name | serine and arginine rich splicing factor 2 |
| Synonyms | PR264|SC-35|SC35|SFRS2|SFRS2A|SRp30b |
| Cytomap | 17q25.1 |
| Type of gene | protein-coding |
| Description | serine/arginine-rich splicing factor 2SR splicing factor 2splicing component, 35 kDasplicing factor SC35splicing factor, arginine/serine-rich 2 |
| Modification date | 20220513 |
| UniProtAcc | Q01130 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| SRSF2 | GO:0000398 | mRNA splicing, via spliceosome | 21873635 | Process |
| SRSF2 | GO:0003723 | RNA binding | 21873635 | Function |
| SRSF2 | GO:0005737 | cytoplasm | 21873635 | Component |
| SRSF2 | GO:0016607 | nuclear speck | 21873635 | Component |
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Spatial pattern events for SRSF2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SRSF2 | Human | Prostate | rep_7 | 29925878 | 9.68e-13 |
| SRSF2 | Human | Bladder | rep_2 | 34385456 | 1.47e-13 |
| SRSF2 | Human | Bladder | rep_3 | 34385456 | 3.31e-06 |
| SRSF2 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| SRSF2 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| SRSF2 | Human | Intestine | rep_colon3 | 34417225 | 1.01e-15 |
| SRSF2 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| SRSF2 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| SRSF2 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| SRSF2 | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| SRSF2 | Human | Intestine | A1 | 33406409 | 6.31e-15 |
| SRSF2 | Human | Intestine | A2 | 33406409 | 7.00e-15 |
| SRSF2 | Human | Intestine | A4 | 33406409 | 1.73e-07 |
| SRSF2 | Human | Uterus | rep_1 | 34857954 | 5.13e-15 |
| SRSF2 | Human | Uterus | rep_2 | 34857954 | 3.73e-12 |
| SRSF2 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| SRSF2 | Human | Uterus | rep_4 | 34857954 | 1.82e-15 |
| SRSF2 | Human | Breast | 1142243F | 34493872 | 2.30e-15 |
| SRSF2 | Human | Breast | 1160920F | 34493872 | 2.05e-08 |
| SRSF2 | Human | Breast | CID4290 | 34493872 | 1.01e-06 |
| SRSF2 | Human | Breast | CID4465 | 34493872 | 4.85e-15 |
| SRSF2 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| SRSF2 | Human | Lung | rep_1 | 35355018 | 1.87e-10 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_2_H&E  |  |
Bladder_rep_3_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon3_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Intestine_A4_H&E  |  |
Uterus_rep_1_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Uterus_rep_4_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4290_H&E  |  |
Breast_CID4465_H&E  |  |
Breast_CID44971_H&E  |  |
Lung_rep_1_H&E  |  |
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Spatial pattern pathway has SRSF2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SRSF2 | GOBP_Cellular_Macromolecule_Localization | Human | Intestine | A3 | 1.7e-09 |
| SRSF2 | GOBP_Establishment_Of_Protein_Localization | Human | Intestine | A3 | 5.0e-10 |
| SRSF2 | GOBP_Establishment_Of_Rna_Localization | Human | Intestine | A3 | 9.7e-11 |
| SRSF2 | GOBP_Intracellular_Protein_Transport | Human | Intestine | A3 | 4.8e-12 |
| SRSF2 | GOBP_Intracellular_Transport | Human | Intestine | A3 | 7.6e-15 |
| SRSF2 | GOBP_Mrna_3_End_Processing | Human | Intestine | A3 | 4.9e-12 |
| SRSF2 | GOBP_Mrna_Export_From_Nucleus | Human | Intestine | A3 | 9.9e-15 |
| SRSF2 | GOBP_Mrna_Metabolic_Process | Human | Intestine | A3 | 7.7e-20 |
| SRSF2 | GOBP_Mrna_Processing | Human | Intestine | A3 | 4.9e-17 |
| SRSF2 | GOBP_Mrna_Transport | Human | Intestine | A3 | 6.6e-09 |
| SRSF2 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Intestine | A3 | 5.9e-17 |
| SRSF2 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 7.7e-14 |
| SRSF2 | GOBP_Nuclear_Export | Human | Intestine | A3 | 3.6e-07 |
| SRSF2 | GOBP_Nuclear_Transport | Human | Intestine | A3 | 5.6e-10 |
| SRSF2 | GOBP_Nucleobase_Containing_Compound_Transport | Human | Intestine | A3 | 2.5e-11 |
| SRSF2 | GOBP_Protein_Containing_Complex_Localization | Human | Intestine | A3 | 6.4e-12 |
| SRSF2 | GOBP_Rna_3_End_Processing | Human | Intestine | A3 | 9.2e-07 |
| SRSF2 | GOBP_Rna_Export_From_Nucleus | Human | Intestine | A3 | 3.3e-10 |
| SRSF2 | GOBP_Rna_Localization | Human | Intestine | A3 | 1.4e-08 |
| SRSF2 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| SRSF2 | GOBP_Rna_Splicing | Human | Intestine | A3 | 3.3e-19 |
| SRSF2 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Intestine | A3 | 2.2e-12 |
| SRSF2 | GOBP_Mrna_Metabolic_Process | Human | Pancreas | PDAC-B-st1 | 2.6e-05 |
| SRSF2 | GOBP_Rna_Export_From_Nucleus | Human | Pancreas | PDAC-B-st1 | 6.7e-05 |
| SRSF2 | GOBP_Rna_Splicing | Human | Pancreas | PDAC-B-st1 | 1.9e-05 |
| SRSF2 | GOBP_Mrna_Export_From_Nucleus | Human | Pancreas | PDAC-A-st2 | 3.9e-08 |
| SRSF2 | GOBP_Nuclear_Export | Human | Uterus | rep_25 | 7.4e-11 |
| SRSF2 | GOBP_Nuclear_Transport | Human | Uterus | rep_25 | 2.3e-13 |
| SRSF2 | GOBP_Establishment_Of_Rna_Localization | Human | Uterus | rep_26 | 8.7e-07 |
| SRSF2 | GOBP_Mrna_Export_From_Nucleus | Human | Uterus | rep_26 | 3.9e-08 |
| SRSF2 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Uterus | rep_26 | 2.1e-06 |
| SRSF2 | GOBP_Rna_Export_From_Nucleus | Human | Uterus | rep_26 | 3.8e-10 |
| SRSF2 | GOBP_Rna_Localization | Human | Uterus | rep_26 | 1.2e-09 |
| SRSF2 | GOBP_Rna_Splicing | Human | Uterus | rep_26 | 1.0e-05 |
| SRSF2 | GOBP_Mrna_3_End_Processing | Human | Uterus | rep_27 | 5.1e-08 |
| SRSF2 | GOBP_Cellular_Macromolecule_Localization | Human | Breast | rep_1 | 3.7e-09 |
| SRSF2 | GOBP_Establishment_Of_Protein_Localization | Human | Breast | rep_1 | 7.2e-05 |
| SRSF2 | GOBP_Intracellular_Protein_Transport | Human | Breast | rep_6 | 6.4e-12 |
| SRSF2 | GOBP_Intracellular_Transport | Human | Breast | rep_6 | 1.3e-08 |
| SRSF2 | GOBP_Mrna_3_End_Processing | Human | Breast | rep_6 | 6.6e-04 |
| SRSF2 | GOBP_Mrna_Export_From_Nucleus | Human | Breast | rep_6 | 1.1e-04 |
| SRSF2 | GOBP_Mrna_Metabolic_Process | Human | Breast | rep_6 | 3.0e-08 |
| SRSF2 | GOBP_Mrna_Processing | Human | Breast | rep_6 | 1.5e-06 |
| SRSF2 | GOBP_Mrna_Transport | Human | Breast | rep_6 | 1.9e-10 |
| SRSF2 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Breast | rep_6 | 2.6e-08 |
| SRSF2 | GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_6 | 3.5e-08 |
| SRSF2 | GOBP_Nuclear_Export | Human | Breast | rep_6 | 1.4e-05 |
| SRSF2 | GOBP_Nuclear_Transport | Human | Breast | rep_6 | 3.1e-08 |
| SRSF2 | GOBP_Protein_Containing_Complex_Localization | Human | Breast | rep_6 | 1.3e-06 |
| SRSF2 | GOBP_Rna_3_End_Processing | Human | Breast | rep_6 | 1.8e-05 |
| SRSF2 | GOBP_Rna_Export_From_Nucleus | Human | Breast | rep_6 | 9.6e-09 |
| SRSF2 | GOBP_Rna_Localization | Human | Breast | rep_6 | 7.7e-05 |
| SRSF2 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| SRSF2 | GOBP_Rna_Splicing | Human | Breast | rep_6 | 1.1e-09 |
| SRSF2 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Breast | rep_6 | 5.4e-08 |
| SRSF2 | GOBP_Nuclear_Transport | Human | Skin | P5_rep1 | 5.0e-19 |
| SRSF2 | GOBP_Mrna_Metabolic_Process | Human | Skin | P5_rep3 | 1.8e-08 |
| SRSF2 | GOBP_Mrna_Processing | Human | Skin | P5_rep3 | 9.7e-09 |
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SRSF2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SRSF2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SRSF2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for SRSF2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SRSF2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
