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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SFPQ (spascer ID:6421)

Gene summary for SFPQ

Gene summary

Gene information
	Species	Human
	Gene symbol	SFPQ
	Gene ID	6421
	Gene name	splicing factor proline and glutamine rich
	Synonyms	POMP100\|PPP1R140\|PSF
	Cytomap	1p34.3
	Type of gene	protein-coding
	Description	splicing factor, proline- and glutamine-rich100 kDa DNA-pairing proteinDNA-binding p52/p100 complex, 100 kDa subunitPTB-associated splicing factorepididymis secretory sperm binding proteinpolypyrimidine tract binding protein associatedpolypyrimidine
	Modification date	20220513
	UniProtAcc	P23246

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SFPQ	GO:0000380	alternative mRNA splicing, via spliceosome	21873635	Process
SFPQ	GO:0005634	nucleus	21873635	Component
SFPQ	GO:0006355	regulation of transcription, DNA-templated	21873635	Process

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Spatial pattern events for SFPQ

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SFPQ	Human	Bladder	rep_2	34385456	6.29e-15
SFPQ	Human	Intestine	rep_colon1	34417225	1.95e-15
SFPQ	Human	Intestine	rep_colon2	34417225	8.12e-16
SFPQ	Human	Intestine	rep_colon3	34417225	1.82e-15
SFPQ	Human	Intestine	rep_colon4	34417225	2.82e-07
SFPQ	Human	Liver	rep_liver1	34417225	1.08e-15
SFPQ	Human	Liver	rep_liver2	34417225	6.98e-16
SFPQ	Human	Liver	rep_liver4	34417225	3.86e-11
SFPQ	Human	Intestine	A1	33406409	6.68e-12
SFPQ	Human	Intestine	A2	33406409	7.00e-15
SFPQ	Human	Intestine	A4	33406409	1.27e-06
SFPQ	Human	Uterus	rep_1	34857954	5.13e-15
SFPQ	Human	Uterus	rep_2	34857954	2.55e-15
SFPQ	Human	Uterus	rep_3	34857954	1.66e-15
SFPQ	Human	Uterus	rep_4	34857954	1.82e-15
SFPQ	Human	Breast	1142243F	34493872	2.30e-15
SFPQ	Human	Breast	CID4290	34493872	3.79e-07
SFPQ	Human	Breast	CID44971	34493872	1.76e-15
SFPQ	Human	Heart	w9_s5	31835037	3.82e-04
SFPQ	Human	Skin	P5_rep2	32946785	5.76e-07
SFPQ	Human	Lung	rep_1	35355018	5.96e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_1142243F_H&E
Breast_CID4290_H&E
Breast_CID44971_H&E
Skin_P5_rep2_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has SFPQ envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SFPQ	GOBP_Activation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
SFPQ	GOBP_Positive_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	3.1e-68
SFPQ	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Human	Brain	rep_1	1.1e-05
SFPQ	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
SFPQ	GOBP_Regulation_Of_Defense_Response	Human	Brain	rep_1	3.1e-41
SFPQ	GOBP_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
SFPQ	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	1.2e-64
SFPQ	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Brain	rep_1	4.6e-05
SFPQ	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
SFPQ	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
SFPQ	GOBP_Innate_Immune_Response	Human	Brain	rep_4	1.2e-64
SFPQ	GOBP_Activation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
SFPQ	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
SFPQ	GOBP_Innate_Immune_Response	Human	Liver	rep_1	7.3e-68
SFPQ	GOBP_Positive_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
SFPQ	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Human	Liver	rep_1	1.2e-71
SFPQ	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
SFPQ	GOBP_Regulation_Of_Defense_Response	Human	Liver	rep_1	3.7e-85
SFPQ	GOBP_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
SFPQ	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
SFPQ	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Liver	rep_1	5.3e-67
SFPQ	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	3.4e-10
SFPQ	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	2.4e-25
SFPQ	GOBP_Activation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
SFPQ	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
SFPQ	GOBP_Innate_Immune_Response	Human	Intestine	rep_colon4	3.4e-69
SFPQ	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
SFPQ	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	rep_colon4	2.0e-10
SFPQ	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
SFPQ	GOBP_Regulation_Of_Defense_Response	Human	Intestine	rep_colon4	5.8e-33
SFPQ	GOBP_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
SFPQ	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	rep_colon4	2.2e-52
SFPQ	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
SFPQ	GOBP_Activation_Of_Immune_Response	Human	Intestine	A3	5.7e-11
SFPQ	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Human	Intestine	A3	1.1e-09
SFPQ	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
SFPQ	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
SFPQ	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
SFPQ	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SFPQ	GOBP_Cellular_Response_To_Chemical_Stress	Human	Intestine	A3	1.1e-11
SFPQ	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
SFPQ	GOBP_Chromatin_Organization	Human	Intestine	A3	3.2e-11
SFPQ	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
SFPQ	GOBP_Chromosome_Segregation	Human	Intestine	A3	4.7e-12
SFPQ	GOBP_Circadian_Rhythm	Human	Intestine	A3	3.1e-07
SFPQ	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
SFPQ	GOBP_Dna_Metabolic_Process	Human	Intestine	A3	1.2e-09
SFPQ	GOBP_Dna_Repair	Human	Intestine	A3	4.4e-09
SFPQ	GOBP_Double_Strand_Break_Repair	Human	Intestine	A3	3.1e-09
SFPQ	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SFPQ	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
SFPQ	GOBP_Histone_Deacetylation	Human	Intestine	A3	7.0e-09
SFPQ	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SFPQ	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SFPQ	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	2.5e-16
SFPQ	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
SFPQ	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
SFPQ	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
SFPQ	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
SFPQ	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
SFPQ	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
SFPQ	GOBP_Nuclear_Chromosome_Segregation	Human	Intestine	A3	4.3e-09
SFPQ	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
SFPQ	GOBP_Positive_Regulation_Of_Apoptotic_Signaling_Pathway	Human	Intestine	A3	1.8e-07
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
SFPQ	GOBP_Positive_Regulation_Of_Cell_Death	Human	Intestine	A3	4.5e-11
SFPQ	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
SFPQ	GOBP_Positive_Regulation_Of_Defense_Response	Human	Intestine	A3	4.2e-19
SFPQ	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	A3	2.4e-07
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	2.6e-10
SFPQ	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
SFPQ	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	3.5e-07
SFPQ	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	A3	8.4e-09
SFPQ	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
SFPQ	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
SFPQ	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
SFPQ	GOBP_Regulation_Of_Apoptotic_Signaling_Pathway	Human	Intestine	A3	1.3e-15
SFPQ	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
SFPQ	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
SFPQ	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
SFPQ	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
SFPQ	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
SFPQ	GOBP_Regulation_Of_Defense_Response	Human	Intestine	A3	1.6e-08
SFPQ	GOBP_Regulation_Of_Immune_Response	Human	Intestine	A3	1.6e-12
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
SFPQ	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	7.5e-12
SFPQ	GOBP_Regulation_Of_Intrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	1.3e-16
SFPQ	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
SFPQ	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	A3	1.0e-09
SFPQ	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
SFPQ	GOBP_Response_To_Oxidative_Stress	Human	Intestine	A3	5.4e-18
SFPQ	GOBP_Rhythmic_Process	Human	Intestine	A3	4.4e-12
SFPQ	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
SFPQ	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
SFPQ	GOBP_Rna_Splicing	Human	Intestine	A3	3.3e-19
SFPQ	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Intestine	A3	2.2e-12
SFPQ	GOBP_Sister_Chromatid_Segregation	Human	Intestine	A3	1.0e-11
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
SFPQ	GOBP_Histone_H3_Deacetylation	Human	Intestine	A8	1.2e-11
SFPQ	GOBP_Microtubule_Based_Movement	Human	Intestine	A8	2.9e-10
SFPQ	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Intestine	A8	9.0e-07
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Intestine	A8	6.9e-14
SFPQ	GOBP_Regulation_Of_Circadian_Rhythm	Human	Intestine	A8	9.8e-12
SFPQ	GOBP_Regulation_Of_Innate_Immune_Response	Human	Intestine	A8	1.3e-11
SFPQ	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Human	Intestine	A8	1.8e-07
SFPQ	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Intestine	A8	4.4e-08
SFPQ	GOBP_Sister_Chromatid_Cohesion	Human	Intestine	A8	5.4e-21
SFPQ	GOBP_Activation_Of_Innate_Immune_Response	Human	Pancreas	PDAC-B-st1	4.0e-05
SFPQ	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Human	Pancreas	PDAC-B-st1	4.0e-05
SFPQ	GOBP_Axo_Dendritic_Protein_Transport	Human	Pancreas	PDAC-B-st1	1.0e-05
SFPQ	GOBP_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
SFPQ	GOBP_Microtubule_Based_Transport	Human	Pancreas	PDAC-B-st1	2.2e-05
SFPQ	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
SFPQ	GOBP_Nuclear_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
SFPQ	GOBP_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Pancreas	PDAC-B-st1	9.8e-05
SFPQ	GOBP_Regulation_Of_Response_To_Oxidative_Stress	Human	Pancreas	PDAC-B-st1	9.8e-05
SFPQ	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Pancreas	PDAC-B-st1	7.2e-05
SFPQ	GOBP_Rna_Splicing	Human	Pancreas	PDAC-B-st1	1.9e-05
SFPQ	GOBP_Transport_Along_Microtubule	Human	Pancreas	PDAC-B-st1	2.0e-05
SFPQ	GOBP_Dendritic_Transport	Human	Pancreas	PDAC-A-st2	3.6e-05
SFPQ	GOBP_Activation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
SFPQ	GOBP_Innate_Immune_Response	Human	Uterus	rep_4	6.1e-31
SFPQ	GOBP_Positive_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
SFPQ	GOBP_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
SFPQ	GOBP_Chromatin_Organization	Human	Uterus	rep_1	1.9e-06
SFPQ	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
SFPQ	GOBP_Activation_Of_Innate_Immune_Response	Human	Uterus	rep_25	3.8e-09
SFPQ	GOBP_Dendritic_Transport	Human	Uterus	rep_25	9.9e-15
SFPQ	GOBP_Histone_H3_Deacetylation	Human	Uterus	rep_25	8.1e-17
SFPQ	GOBP_Negative_Regulation_Of_Circadian_Rhythm	Human	Uterus	rep_25	9.3e-17
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Uterus	rep_25	1.1e-06
SFPQ	GOBP_Positive_Regulation_Of_Sister_Chromatid_Cohesion	Human	Uterus	rep_25	1.9e-16
SFPQ	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
SFPQ	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
SFPQ	GOBP_Chromosome_Segregation	Human	Uterus	rep_26	5.6e-19
SFPQ	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
SFPQ	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
SFPQ	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
SFPQ	GOBP_Nuclear_Chromosome_Segregation	Human	Uterus	rep_26	1.5e-12
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
SFPQ	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	1.7e-06
SFPQ	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_Pathway	Human	Uterus	rep_26	3.9e-14
SFPQ	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
SFPQ	GOBP_Regulation_Of_Circadian_Rhythm	Human	Uterus	rep_26	1.3e-06
SFPQ	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Uterus	rep_26	1.2e-08
SFPQ	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
SFPQ	GOBP_Rna_Splicing	Human	Uterus	rep_26	1.0e-05
SFPQ	GOBP_Sister_Chromatid_Cohesion	Human	Uterus	rep_26	3.1e-15
SFPQ	GOBP_Sister_Chromatid_Segregation	Human	Uterus	rep_26	3.3e-13
SFPQ	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Human	Uterus	rep_28	8.0e-06
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Uterus	rep_29	5.5e-06
SFPQ	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Human	Uterus	rep_29	5.3e-06
SFPQ	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SFPQ	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
SFPQ	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SFPQ	GOBP_Positive_Regulation_Of_Cell_Death	Human	Breast	rep_1	2.2e-15
SFPQ	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
SFPQ	GOBP_Positive_Regulation_Of_Defense_Response	Human	Breast	rep_1	1.8e-25
SFPQ	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Human	Breast	rep_1	3.0e-07
SFPQ	GOBP_Protein_Transport_Along_Microtubule	Human	Breast	rep_1	4.0e-37
SFPQ	GOBP_Recombinational_Repair	Human	Breast	rep_1	2.9e-09
SFPQ	GOBP_Regulation_Of_Defense_Response	Human	Breast	rep_1	1.1e-15
SFPQ	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
SFPQ	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Breast	rep_1	2.9e-17
SFPQ	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
SFPQ	GOBP_Axo_Dendritic_Protein_Transport	Human	Breast	rep_5	3.3e-14
SFPQ	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	5.3e-08
SFPQ	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Breast	rep_5	8.2e-05
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_5	9.5e-05
SFPQ	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Human	Breast	rep_5	1.3e-05
SFPQ	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
SFPQ	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
SFPQ	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
SFPQ	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
SFPQ	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	8.7e-11
SFPQ	GOBP_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_5	5.9e-08
SFPQ	GOBP_Response_To_Oxidative_Stress	Human	Breast	rep_5	1.0e-04
SFPQ	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Human	Breast	rep_6	2.3e-06
SFPQ	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
SFPQ	GOBP_Axo_Dendritic_Transport	Human	Breast	rep_6	1.5e-05
SFPQ	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
SFPQ	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
SFPQ	GOBP_Cell_Death_In_Response_To_Oxidative_Stress	Human	Breast	rep_6	1.9e-04
SFPQ	GOBP_Cellular_Response_To_Chemical_Stress	Human	Breast	rep_6	3.6e-05
SFPQ	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
SFPQ	GOBP_Chromatin_Organization	Human	Breast	rep_6	4.3e-07
SFPQ	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
SFPQ	GOBP_Chromosome_Segregation	Human	Breast	rep_6	1.9e-05
SFPQ	GOBP_Circadian_Rhythm	Human	Breast	rep_6	9.3e-08
SFPQ	GOBP_Dna_Metabolic_Process	Human	Breast	rep_6	1.4e-10
SFPQ	GOBP_Dna_Recombination	Human	Breast	rep_6	1.4e-06
SFPQ	GOBP_Dna_Repair	Human	Breast	rep_6	1.0e-09
SFPQ	GOBP_Double_Strand_Break_Repair	Human	Breast	rep_6	2.0e-09
SFPQ	GOBP_Histone_Deacetylation	Human	Breast	rep_6	1.3e-06
SFPQ	GOBP_Histone_H3_Deacetylation	Human	Breast	rep_6	2.6e-05
SFPQ	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SFPQ	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SFPQ	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	2.7e-08
SFPQ	GOBP_Macromolecule_Deacylation	Human	Breast	rep_6	2.0e-04
SFPQ	GOBP_Microtubule_Based_Movement	Human	Breast	rep_6	8.5e-09
SFPQ	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
SFPQ	GOBP_Microtubule_Based_Transport	Human	Breast	rep_6	2.9e-09
SFPQ	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
SFPQ	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
SFPQ	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
SFPQ	GOBP_Negative_Regulation_Of_Circadian_Rhythm	Human	Breast	rep_6	1.5e-06
SFPQ	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
SFPQ	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
SFPQ	GOBP_Nuclear_Chromosome_Segregation	Human	Breast	rep_6	4.6e-06
SFPQ	GOBP_Positive_Regulation_Of_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	2.5e-08
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
SFPQ	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	1.4e-12
SFPQ	GOBP_Positive_Regulation_Of_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	5.0e-06
SFPQ	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
SFPQ	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
SFPQ	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
SFPQ	GOBP_Regulation_Of_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	1.6e-07
SFPQ	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
SFPQ	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
SFPQ	GOBP_Regulation_Of_Circadian_Rhythm	Human	Breast	rep_6	2.4e-10
SFPQ	GOBP_Regulation_Of_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	3.3e-09
SFPQ	GOBP_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Breast	rep_6	1.8e-05
SFPQ	GOBP_Regulation_Of_Response_To_Oxidative_Stress	Human	Breast	rep_6	8.1e-05
SFPQ	GOBP_Rhythmic_Process	Human	Breast	rep_6	1.0e-11
SFPQ	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
SFPQ	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
SFPQ	GOBP_Rna_Splicing	Human	Breast	rep_6	1.1e-09
SFPQ	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Breast	rep_6	5.4e-08
SFPQ	GOBP_Sister_Chromatid_Cohesion	Human	Breast	rep_6	1.9e-04
SFPQ	GOBP_Sister_Chromatid_Segregation	Human	Breast	rep_6	5.3e-04
SFPQ	GOBP_Transport_Along_Microtubule	Human	Breast	rep_6	1.5e-05
SFPQ	GOBP_Protein_Transport_Along_Microtubule	Human	Skin	P2_rep2	6.1e-18
SFPQ	GOBP_Dna_Repair	Human	Skin	P5_rep1	1.7e-08
SFPQ	GOBP_Microtubule_Based_Movement	Human	Skin	P5_rep1	2.1e-08
SFPQ	GOBP_Nuclear_Chromosome_Segregation	Human	Skin	P5_rep1	7.9e-09
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
SFPQ	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Cell_Death	Human	Skin	P5_rep1	2.1e-12
SFPQ	GOBP_Regulation_Of_Circadian_Rhythm	Human	Skin	P5_rep1	7.4e-08
SFPQ	GOBP_Axo_Dendritic_Transport	Human	Skin	P5_rep3	4.8e-11
SFPQ	GOBP_Macromolecule_Deacylation	Human	Skin	P5_rep3	6.7e-10
SFPQ	GOBP_Microtubule_Based_Transport	Human	Skin	P5_rep3	8.3e-08
SFPQ	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
SFPQ	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
SFPQ	GOBP_Negative_Regulation_Of_Circadian_Rhythm	Human	Skin	P5_rep3	1.0e-12
SFPQ	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
SFPQ	GOBP_Positive_Regulation_Of_Sister_Chromatid_Cohesion	Human	Skin	P5_rep3	8.7e-11
SFPQ	GOBP_Transport_Along_Microtubule	Human	Skin	P5_rep3	7.3e-13
SFPQ	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Skin	P9_rep3	4.3e-09
SFPQ	GOBP_Activation_Of_Innate_Immune_Response	Human	Skin	P10_rep2	5.4e-20
SFPQ	GOBP_Axo_Dendritic_Protein_Transport	Human	Skin	P10_rep2	6.7e-11
SFPQ	GOBP_Histone_H3_Deacetylation	Human	Skin	P10_rep2	2.5e-18
SFPQ	GOBP_Positive_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_Pathway	Human	Skin	P10_rep2	8.2e-11
SFPQ	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Skin	P10_rep2	9.2e-18
SFPQ	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
SFPQ	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
SFPQ	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
SFPQ	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
SFPQ	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Human	Lung	rep_1	4.1e-09
SFPQ	GOBP_Positive_Regulation_Of_Cell_Death	Human	Lung	rep_2	3.0e-07

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SFPQ function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SFPQ function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SFPQ envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Sfpq	Kidney	IRI	VSM	Btg2,Dph2,Dennd2d, etc.	0.391
SFPQ	Uterus	proliferative	SOX9	HNRNPU,RBM39,BPTF, etc.	0.569
SFPQ	Uterus	proliferative	SOX9_LGR5	HNRNPU,RBM39,BPTF, etc.	0.313
SFPQ	Uterus	proliferative	SOX9_prolif	HNRNPU,RBM39,BPTF, etc.	0.349

Motif information.

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Related Drugs for SFPQ

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
SFPQ	P23246	DB09130	Copper	Splicing factor, proline- and glutamine-rich	SmallMoleculeDrug	approved\|investigational

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Related Diseases for SFPQ

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SFPQ	C4518356	MiT family translocation renal cell carcinoma	2	ORPHANET
SFPQ	C0019693	HIV Infections	1	CTD_human
SFPQ	C0037274	Dermatologic disorders	1	CTD_human
SFPQ	C0274861	Arsenic Poisoning, Inorganic	1	CTD_human
SFPQ	C0274862	Nervous System, Organic Arsenic Poisoning	1	CTD_human
SFPQ	C0311375	Arsenic Poisoning	1	CTD_human
SFPQ	C0751851	Arsenic Encephalopathy	1	CTD_human
SFPQ	C0751852	Arsenic Induced Polyneuropathy	1	CTD_human
SFPQ	C4505456	HIV Coinfection	1	CTD_human