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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: BLMH (spascer ID:642)

Gene summary for BLMH

Gene summary

Gene information
	Species	Human
	Gene symbol	BLMH
	Gene ID	642
	Gene name	bleomycin hydrolase
	Synonyms	BH\|BMH
	Cytomap	17q11.2
	Type of gene	protein-coding
	Description	bleomycin hydrolaseBLM hydrolase
	Modification date	20220513
	UniProtAcc	Q13867

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
BLMH	GO:0005737	cytoplasm	21873635	Component
BLMH	GO:0008234	cysteine-type peptidase activity	21873635	Function
BLMH	GO:0009636	response to toxic substance	21873635	Process
BLMH	GO:0043418	homocysteine catabolic process	21873635	Process

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Spatial pattern events for BLMH

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
BLMH	Human	Liver	rep_liver1	34417225	1.08e-15
BLMH	Human	Liver	rep_liver2	34417225	6.98e-16
BLMH	Human	Uterus	rep_3	34857954	1.66e-15
BLMH	Human	Breast	CID44971	34493872	6.33e-15
BLMH	Human	Skin	P2_rep1	32946785	1.56e-14
BLMH	Human	Skin	P2_rep2	32946785	5.48e-15
BLMH	Human	Skin	P2_rep3	32946785	5.90e-15
BLMH	Human	Skin	P10_rep2	32946785	1.72e-07
BLMH	Human	Skin	P10_rep3	32946785	6.27e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_3_H&E
Breast_CID44971_H&E
Skin_P2_rep3_H&E
Skin_P10_rep2_H&E
Skin_P10_rep3_H&E

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Spatial pattern pathway has BLMH envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
BLMH	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
BLMH	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
BLMH	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
BLMH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
BLMH	GOBP_Protein_Polyubiquitination	Human	Intestine	A3	2.1e-10
BLMH	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
BLMH	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Intestine	A8	7.0e-13
BLMH	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Intestine	A8	2.5e-14
BLMH	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.3e-13
BLMH	GOBP_Homocysteine_Metabolic_Process	Human	Intestine	A8	1.5e-09
BLMH	GOBP_Organic_Acid_Catabolic_Process	Human	Intestine	A8	1.6e-12
BLMH	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
BLMH	GOBP_Response_To_Toxic_Substance	Human	Intestine	A8	8.6e-21
BLMH	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
BLMH	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
BLMH	GOBP_Sulfur_Amino_Acid_Catabolic_Process	Human	Intestine	A8	2.0e-15
BLMH	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Intestine	A8	2.0e-15
BLMH	GOBP_Sulfur_Compound_Catabolic_Process	Human	Intestine	A8	4.4e-08
BLMH	GOBP_Sulfur_Compound_Metabolic_Process	Human	Intestine	A8	2.5e-14
BLMH	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Pancreas	PDAC-A-st2	9.6e-05
BLMH	GOBP_Alpha_Amino_Acid_Catabolic_Process	Human	Uterus	rep_25	1.2e-11
BLMH	GOBP_Protein_Polyubiquitination	Human	Uterus	rep_25	1.1e-17
BLMH	GOBP_Sulfur_Amino_Acid_Catabolic_Process	Human	Uterus	rep_25	7.6e-16
BLMH	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	1.6e-06
BLMH	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Uterus	rep_26	3.2e-12
BLMH	GOBP_Organic_Acid_Catabolic_Process	Human	Uterus	rep_26	6.9e-09
BLMH	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
BLMH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
BLMH	GOBP_Response_To_Toxic_Substance	Human	Uterus	rep_26	4.2e-06
BLMH	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
BLMH	GOBP_Sulfur_Compound_Metabolic_Process	Human	Uterus	rep_26	8.8e-08
BLMH	GOBP_Sulfur_Amino_Acid_Catabolic_Process	Human	Breast	rep_1	6.6e-04
BLMH	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
BLMH	GOBP_Response_To_Toxic_Substance	Human	Breast	rep_5	1.2e-07
BLMH	GOBP_Alpha_Amino_Acid_Catabolic_Process	Human	Breast	rep_6	2.6e-05
BLMH	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.7e-08
BLMH	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Breast	rep_6	1.6e-05
BLMH	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.0e-10
BLMH	GOBP_Organic_Acid_Catabolic_Process	Human	Breast	rep_6	1.5e-11
BLMH	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
BLMH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
BLMH	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
BLMH	GOBP_Protein_Polyubiquitination	Human	Breast	rep_6	6.3e-04
BLMH	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
BLMH	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
BLMH	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	2.0e-06
BLMH	GOBP_Sulfur_Compound_Catabolic_Process	Human	Breast	rep_6	4.7e-11
BLMH	GOBP_Sulfur_Compound_Metabolic_Process	Human	Breast	rep_6	3.0e-10
BLMH	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Skin	P2_rep2	2.4e-08
BLMH	GOBP_Homocysteine_Metabolic_Process	Human	Skin	P10_rep1	4.7e-09
BLMH	GOBP_Sulfur_Amino_Acid_Catabolic_Process	Human	Skin	P10_rep2	7.1e-12

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BLMH function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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BLMH function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for BLMH envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for BLMH

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for BLMH

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source