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Spatial pattern gene: SELENOP (spascer ID:6414) |
Gene summary for SELENOP |
Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SELENOP | Gene ID | 6414 |
| Gene name | selenoprotein P |
| Synonyms | SELP|SEPP|SEPP1|SeP |
| Cytomap | 5p12 |
| Type of gene | protein-coding |
| Description | selenoprotein Pselenoprotein P, plasma, 1 |
| Modification date | 20220513 |
| UniProtAcc | P49908 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| SELENOP | GO:0001887 | selenium compound metabolic process | 21873635 | Process |
| SELENOP | GO:0005576 | extracellular region | 21873635 | Component |
| SELENOP | GO:0008430 | selenium binding | 21873635 | Function |
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Spatial pattern events for SELENOP |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SELENOP | Human | Brain | rep_1 | 33558695 | 5.52e-15 |
| SELENOP | Human | Brain | rep_2 | 33558695 | 5.18e-14 |
| SELENOP | Human | Brain | rep_3 | 33558695 | 4.93e-15 |
| SELENOP | Human | Brain | rep_4 | 33558695 | 6.08e-15 |
| SELENOP | Human | Brain | rep_6 | 33558695 | 3.74e-13 |
| SELENOP | Human | Brain | rep_7 | 33558695 | 1.65e-14 |
| SELENOP | Human | Brain | rep_8 | 33558695 | 3.31e-14 |
| SELENOP | Human | Brain | rep_9 | 33558695 | 5.33e-15 |
| SELENOP | Human | Brain | rep_10 | 33558695 | 3.23e-15 |
| SELENOP | Human | Brain | rep_11 | 33558695 | 3.36e-15 |
| SELENOP | Human | Brain | rep_12 | 33558695 | 3.65e-15 |
| SELENOP | Human | Bladder | rep_1 | 34385456 | 8.93e-15 |
| SELENOP | Human | Bladder | rep_3 | 34385456 | 3.44e-11 |
| SELENOP | Human | Liver | rep_1 | 34792289 | 3.43e-14 |
| SELENOP | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| SELENOP | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| SELENOP | Human | Intestine | rep_colon3 | 34417225 | 1.01e-15 |
| SELENOP | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| SELENOP | Human | Liver | rep_liver1 | 34417225 | 1.89e-15 |
| SELENOP | Human | Liver | rep_liver2 | 34417225 | 1.27e-15 |
| SELENOP | Human | Liver | rep_liver3 | 34417225 | 3.51e-15 |
| SELENOP | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| SELENOP | Human | Intestine | A1 | 33406409 | 2.09e-15 |
| SELENOP | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| SELENOP | Human | Intestine | A3 | 33406409 | 1.38e-14 |
| SELENOP | Human | Intestine | A4 | 33406409 | 7.35e-15 |
| SELENOP | Human | Intestine | A6 | 33406409 | 8.60e-14 |
| SELENOP | Human | Intestine | A7 | 33406409 | 1.45e-13 |
| SELENOP | Human | Intestine | A8 | 33406409 | 2.47e-14 |
| SELENOP | Human | Intestine | A9 | 33406409 | 2.99e-14 |
| SELENOP | Human | Pancreas | PDAC-G-st1 | 31932730 | 3.13e-12 |
| SELENOP | Human | Uterus | rep_1 | 34857954 | 5.13e-15 |
| SELENOP | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| SELENOP | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| SELENOP | Human | Uterus | rep_4 | 34857954 | 1.82e-15 |
| SELENOP | Human | Breast | 1142243F | 34493872 | 2.30e-15 |
| SELENOP | Human | Breast | 1160920F | 34493872 | 1.48e-15 |
| SELENOP | Human | Breast | CID4290 | 34493872 | 1.64e-07 |
| SELENOP | Human | Breast | CID4465 | 34493872 | 4.85e-15 |
| SELENOP | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| SELENOP | Human | Breast | CID4535 | 34493872 | 6.37e-15 |
| SELENOP | Human | Lung | rep_1 | 35355018 | 4.99e-15 |
| SELENOP | Human | Lung | rep_2 | 35355018 | 1.83e-14 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has SELENOP envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SELENOP | GOBP_Platelet_Degranulation | Human | Brain | st | 2.6e-38 |
| SELENOP | GOBP_Exocytosis | Human | Intestine | A3 | 4.7e-10 |
| SELENOP | GOBP_Response_To_Oxidative_Stress | Human | Intestine | A3 | 5.4e-18 |
| SELENOP | GOBP_Secretion | Human | Intestine | A3 | 1.8e-13 |
| SELENOP | GOBP_Platelet_Degranulation | Human | Intestine | A8 | 7.1e-10 |
| SELENOP | GOBP_Platelet_Degranulation | Human | Uterus | rep_25 | 3.9e-10 |
| SELENOP | GOBP_Exocytosis | Human | Uterus | rep_26 | 5.1e-10 |
| SELENOP | GOBP_Exocytosis | Human | Breast | rep_1 | 2.8e-29 |
| SELENOP | GOBP_Platelet_Degranulation | Human | Breast | rep_1 | 1.7e-261 |
| SELENOP | GOBP_Secretion | Human | Breast | rep_1 | 9.7e-57 |
| SELENOP | GOBP_Response_To_Oxidative_Stress | Human | Breast | rep_5 | 1.0e-04 |
| SELENOP | GOBP_Platelet_Degranulation | Human | Skin | P10_rep1 | 6.2e-14 |
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SELENOP function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SELENOP function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SELENOP envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for SELENOP |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| SELENOP | P49908 | DB14548 | Zinc sulfate, unspecified form | Selenoprotein P | SmallMoleculeDrug | approved|experimental |
| SELENOP | P49908 | DB01593 | Zinc | Selenoprotein P | SmallMoleculeDrug | approved|investigational |
| SELENOP | P49908 | DB14487 | Zinc acetate | Selenoprotein P | SmallMoleculeDrug | approved|investigational |
| SELENOP | P49908 | DB14533 | Zinc chloride | Selenoprotein P | SmallMoleculeDrug | approved|investigational |
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Related Diseases for SELENOP |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |