Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SDC2 (spascer ID:6383)

Gene summary for SDC2

Gene summary

Gene information
	Species	Human
	Gene symbol	SDC2
	Gene ID	6383
	Gene name	syndecan 2
	Synonyms	CD362\|HSPG\|HSPG1\|SYND2
	Cytomap	8q22.1
	Type of gene	protein-coding
	Description	syndecan-2cell surface-associated heparan sulfate proteoglycan 1fibroglycanheparan sulfate proteoglycan 1, cell surface-associatedheparan sulfate proteoglycan core proteinsyndecan proteoglycan 2
	Modification date	20220513
	UniProtAcc	P34741

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SDC2	GO:0009986	cell surface	21873635	Component
SDC2	GO:0016477	cell migration	21873635	Process
SDC2	GO:0048813	dendrite morphogenesis	21873635	Process

Top

Spatial pattern events for SDC2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SDC2	Human	Intestine	rep_colon1	34417225	1.95e-15
SDC2	Human	Intestine	rep_colon2	34417225	8.12e-16
SDC2	Human	Intestine	rep_colon3	34417225	1.29e-07
SDC2	Human	Liver	rep_liver1	34417225	3.57e-15
SDC2	Human	Liver	rep_liver2	34417225	6.98e-16
SDC2	Human	Liver	rep_liver3	34417225	3.51e-15
SDC2	Human	Liver	rep_liver4	34417225	7.71e-16
SDC2	Human	Uterus	rep_2	34857954	4.27e-10
SDC2	Human	Uterus	rep_3	34857954	1.66e-15
SDC2	Human	Breast	1142243F	34493872	2.30e-15
SDC2	Human	Breast	CID4290	34493872	1.33e-06
SDC2	Human	Breast	CID4465	34493872	2.59e-13
SDC2	Human	Breast	CID44971	34493872	1.76e-15
SDC2	Human	Breast	CID4535	34493872	6.37e-15
SDC2	Human	Heart	w6_s3	31835037	5.32e-10
SDC2	Human	Heart	w6_s4	31835037	1.37e-10
SDC2	Human	Heart	w6_s5	31835037	7.68e-03
SDC2	Human	Heart	w9_s5	31835037	1.54e-07
SDC2	Human	Heart	w9_s6	31835037	6.69e-03
SDC2	Human	Skin	P2_rep3	32946785	5.22e-06
SDC2	Human	Skin	mel1_rep1	30154148	1.03e-08
SDC2	Human	Skin	mel1_rep2	30154148	1.74e-08
SDC2	Human	Lung	rep_1	35355018	4.99e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_1142243F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Lung_rep_1_H&E

Top

Spatial pattern pathway has SDC2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SDC2	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
SDC2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
SDC2	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
SDC2	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
SDC2	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
SDC2	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
SDC2	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
SDC2	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
SDC2	GOBP_Cell_Morphogenesis	Human	Brain	rep_4	1.0e-14
SDC2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Brain	rep_4	4.1e-17
SDC2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Bladder	rep_2	1.3e-05
SDC2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Bladder	rep_4	3.0e-06
SDC2	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
SDC2	GOBP_Cell_Morphogenesis	Human	Liver	rep_1	2.1e-52
SDC2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
SDC2	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
SDC2	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
SDC2	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
SDC2	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
SDC2	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
SDC2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Liver	rep_1	1.0e-70
SDC2	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
SDC2	GOBP_Cell_Morphogenesis	Human	Intestine	rep_colon2	1.5e-57
SDC2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
SDC2	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
SDC2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	rep_colon4	9.0e-12
SDC2	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
SDC2	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
SDC2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Intestine	A3	1.8e-09
SDC2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
SDC2	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
SDC2	GOBP_Cell_Morphogenesis	Human	Intestine	A3	9.7e-08
SDC2	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Intestine	A3	3.7e-07
SDC2	GOBP_Cell_Part_Morphogenesis	Human	Intestine	A3	8.9e-08
SDC2	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
SDC2	GOBP_Dendrite_Morphogenesis	Human	Intestine	A3	1.6e-08
SDC2	GOBP_Leukocyte_Migration	Human	Intestine	A3	1.5e-08
SDC2	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
SDC2	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
SDC2	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
SDC2	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
SDC2	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
SDC2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
SDC2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	A3	4.8e-12
SDC2	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
SDC2	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Intestine	A3	2.0e-09
SDC2	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Intestine	A3	2.0e-11
SDC2	GOBP_Aminoglycan_Biosynthetic_Process	Human	Intestine	A8	6.2e-18
SDC2	GOBP_Aminoglycan_Catabolic_Process	Human	Intestine	A8	5.0e-10
SDC2	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Intestine	A8	3.2e-10
SDC2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
SDC2	GOBP_Ephrin_Receptor_Signaling_Pathway	Human	Intestine	A8	7.6e-20
SDC2	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
SDC2	GOBP_Regulation_Of_Dendrite_Morphogenesis	Human	Intestine	A8	4.5e-07
SDC2	GOBP_Isoprenoid_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.0e-05
SDC2	GOBP_Aminoglycan_Biosynthetic_Process	Human	Pancreas	PDAC-A-st2	8.4e-06
SDC2	GOBP_Regulation_Of_Dendrite_Morphogenesis	Human	Pancreas	PDAC-A-st2	4.1e-05
SDC2	GOBP_Regulation_Of_Dendrite_Development	Human	Uterus	rep_1	6.4e-06
SDC2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Uterus	rep_26	3.5e-11
SDC2	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Uterus	rep_26	5.1e-11
SDC2	GOBP_Dendrite_Development	Human	Uterus	rep_26	3.9e-07
SDC2	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
SDC2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
SDC2	GOBP_Regulation_Of_Dendrite_Morphogenesis	Human	Uterus	rep_26	2.1e-06
SDC2	GOBP_Terpenoid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
SDC2	GOBP_Leukocyte_Migration	Human	Uterus	rep_29	1.5e-07
SDC2	GOBP_Aminoglycan_Biosynthetic_Process	Human	Breast	rep_1	1.4e-24
SDC2	GOBP_Aminoglycan_Metabolic_Process	Human	Breast	rep_1	2.4e-24
SDC2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Breast	rep_1	2.1e-06
SDC2	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
SDC2	GOBP_Cell_Morphogenesis	Human	Breast	rep_1	5.7e-26
SDC2	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Breast	rep_1	1.6e-61
SDC2	GOBP_Cell_Morphogenesis_Involved_In_Neuron_Differentiation	Human	Breast	rep_1	1.4e-48
SDC2	GOBP_Cell_Part_Morphogenesis	Human	Breast	rep_1	6.2e-28
SDC2	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
SDC2	GOBP_Cellular_Component_Morphogenesis	Human	Breast	rep_1	2.7e-58
SDC2	GOBP_Dendrite_Morphogenesis	Human	Breast	rep_1	6.4e-04
SDC2	GOBP_Ephrin_Receptor_Signaling_Pathway	Human	Breast	rep_1	2.2e-07
SDC2	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
SDC2	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
SDC2	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
SDC2	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
SDC2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Breast	rep_1	4.6e-22
SDC2	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
SDC2	GOBP_Regulation_Of_Dendrite_Morphogenesis	Human	Breast	rep_1	6.1e-47
SDC2	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Breast	rep_1	7.3e-24
SDC2	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Breast	rep_1	1.4e-14
SDC2	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Breast	rep_5	1.1e-09
SDC2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
SDC2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Breast	rep_5	4.6e-14
SDC2	GOBP_Leukocyte_Migration	Human	Breast	rep_5	6.0e-14
SDC2	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
SDC2	GOBP_Post_Translational_Protein_Modification	Human	Breast	rep_5	9.8e-05
SDC2	GOBP_Regulation_Of_Dendrite_Development	Human	Breast	rep_5	1.2e-09
SDC2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
SDC2	GOBP_Dendrite_Development	Human	Breast	rep_6	6.3e-05
SDC2	GOBP_Isoprenoid_Metabolic_Process	Human	Breast	rep_6	3.7e-11
SDC2	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
SDC2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
SDC2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
SDC2	GOBP_Terpenoid_Metabolic_Process	Human	Breast	rep_6	1.1e-10
SDC2	GOBP_Cell_Morphogenesis_Involved_In_Neuron_Differentiation	Human	Skin	P2_rep1	9.6e-08
SDC2	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Skin	P5_rep1	1.1e-09
SDC2	GOBP_Dendrite_Development	Human	Skin	P5_rep1	3.7e-10
SDC2	GOBP_Dendrite_Morphogenesis	Human	Skin	P5_rep1	3.2e-11
SDC2	GOBP_Regulation_Of_Dendrite_Development	Human	Skin	P5_rep1	5.3e-08
SDC2	GOBP_Regulation_Of_Dendrite_Morphogenesis	Human	Skin	P10_rep1	2.2e-13

Top

SDC2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

SDC2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
TNFSF13	SDC2	TNFSF13_SDC2	Lung	rep_1
FN1	SDC2	FN1_SDC2	Uterus	rep_3
KNG1	SDC2	KNG1_SDC2	Liver	rep_liver4
TGFB1	SDC2	TGFB1_SDC2	Breast	CID4290

Top

Transcription factor for SDC2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for SDC2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
SDC2	P34741	DB00020	Sargramostim	Syndecan-2	BiotechDrug	approved\|investigational

Top

Related Diseases for SDC2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source