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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: BHMT (spascer ID:635)

Gene summary for BHMT

Gene summary

Gene information
	Species	Human
	Gene symbol	BHMT
	Gene ID	635
	Gene name	betaine--homocysteine S-methyltransferase
	Synonyms	BHMT1\|HEL-S-61p
	Cytomap	5q14.1
	Type of gene	protein-coding
	Description	betaine--homocysteine S-methyltransferase 1epididymis secretory sperm binding protein Li 61p
	Modification date	20220513
	UniProtAcc	Q93088

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
BHMT	GO:0047150	betaine-homocysteine S-methyltransferase activity	21873635	Function

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Spatial pattern events for BHMT

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
BHMT	Human	Bladder	rep_1	34385456	8.93e-15
BHMT	Human	Liver	rep_1	34792289	1.45e-07
BHMT	Human	Liver	rep_liver1	34417225	1.89e-15
BHMT	Human	Liver	rep_liver2	34417225	1.27e-15
BHMT	Human	Liver	rep_liver3	34417225	3.51e-15
BHMT	Human	Liver	rep_liver4	34417225	7.71e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_1_H&E
Liver_rep_1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E

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Spatial pattern pathway has BHMT envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Brain	st	9.7e-07
BHMT	GOBP_Methylation	Human	Intestine	A3	5.9e-09
BHMT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
BHMT	GOBP_Protein_Methylation	Human	Intestine	A3	7.4e-07
BHMT	GOBP_Regulation_Of_Cellular_Amino_Acid_Metabolic_Process	Human	Intestine	A3	9.0e-07
BHMT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Intestine	A8	7.0e-13
BHMT	GOBP_Amine_Catabolic_Process	Human	Intestine	A8	3.4e-19
BHMT	GOBP_Amine_Metabolic_Process	Human	Intestine	A8	7.2e-16
BHMT	GOBP_Amino_Acid_Betaine_Metabolic_Process	Human	Intestine	A8	1.9e-15
BHMT	GOBP_Amino_Acid_Salvage	Human	Intestine	A8	6.0e-11
BHMT	GOBP_Ammonium_Ion_Metabolic_Process	Human	Intestine	A8	6.1e-14
BHMT	GOBP_Aspartate_Family_Amino_Acid_Biosynthetic_Process	Human	Intestine	A8	2.5e-12
BHMT	GOBP_Aspartate_Family_Amino_Acid_Metabolic_Process	Human	Intestine	A8	1.4e-09
BHMT	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Human	Intestine	A8	3.7e-12
BHMT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.3e-13
BHMT	GOBP_Cellular_Ketone_Metabolic_Process	Human	Intestine	A8	1.2e-11
BHMT	GOBP_Cellular_Metabolic_Compound_Salvage	Human	Intestine	A8	2.4e-22
BHMT	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Human	Intestine	A8	9.9e-17
BHMT	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.4e-11
BHMT	GOBP_Choline_Metabolic_Process	Human	Intestine	A8	2.1e-12
BHMT	GOBP_Homocysteine_Metabolic_Process	Human	Intestine	A8	1.5e-09
BHMT	GOBP_Methionine_Biosynthetic_Process	Human	Intestine	A8	6.7e-08
BHMT	GOBP_Methionine_Metabolic_Process	Human	Intestine	A8	5.1e-15
BHMT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
BHMT	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
BHMT	GOBP_Regulation_Of_Cellular_Amine_Metabolic_Process	Human	Intestine	A8	1.0e-15
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Intestine	A8	3.2e-08
BHMT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Intestine	A8	1.7e-14
BHMT	GOBP_Regulation_Of_Sulfur_Metabolic_Process	Human	Intestine	A8	3.2e-20
BHMT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
BHMT	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
BHMT	GOBP_Sulfur_Amino_Acid_Biosynthetic_Process	Human	Intestine	A8	2.6e-11
BHMT	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Intestine	A8	2.0e-15
BHMT	GOBP_Sulfur_Compound_Biosynthetic_Process	Human	Intestine	A8	4.5e-20
BHMT	GOBP_Sulfur_Compound_Metabolic_Process	Human	Intestine	A8	2.5e-14
BHMT	GOBP_Aspartate_Family_Amino_Acid_Biosynthetic_Process	Human	Pancreas	PDAC-B-st1	6.6e-05
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
BHMT	GOBP_Amino_Acid_Betaine_Metabolic_Process	Human	Pancreas	PDAC-A-st2	2.9e-06
BHMT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Pancreas	PDAC-A-st2	9.6e-05
BHMT	GOBP_Regulation_Of_Cellular_Amino_Acid_Metabolic_Process	Human	Pancreas	PDAC-A-st2	6.0e-12
BHMT	GOBP_Amine_Catabolic_Process	Human	Uterus	rep_25	1.9e-13
BHMT	GOBP_Amino_Acid_Salvage	Human	Uterus	rep_25	5.6e-08
BHMT	GOBP_Aspartate_Family_Amino_Acid_Biosynthetic_Process	Human	Uterus	rep_25	1.4e-14
BHMT	GOBP_Aspartate_Family_Amino_Acid_Metabolic_Process	Human	Uterus	rep_25	8.0e-08
BHMT	GOBP_Choline_Metabolic_Process	Human	Uterus	rep_25	5.6e-16
BHMT	GOBP_Methionine_Biosynthetic_Process	Human	Uterus	rep_25	1.1e-10
BHMT	GOBP_Methionine_Metabolic_Process	Human	Uterus	rep_25	4.9e-19
BHMT	GOBP_Sulfur_Amino_Acid_Biosynthetic_Process	Human	Uterus	rep_25	4.1e-09
BHMT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	1.6e-06
BHMT	GOBP_Ammonium_Ion_Metabolic_Process	Human	Uterus	rep_26	8.1e-14
BHMT	GOBP_Cellular_Ketone_Metabolic_Process	Human	Uterus	rep_26	3.2e-13
BHMT	GOBP_Cellular_Metabolic_Compound_Salvage	Human	Uterus	rep_26	7.8e-06
BHMT	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	8.7e-10
BHMT	GOBP_Methylation	Human	Uterus	rep_26	1.9e-06
BHMT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
BHMT	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
BHMT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
BHMT	GOBP_Protein_Methylation	Human	Uterus	rep_26	1.8e-11
BHMT	GOBP_Regulation_Of_Cellular_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	8.6e-06
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Uterus	rep_26	2.1e-10
BHMT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.0e-14
BHMT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
BHMT	GOBP_Sulfur_Compound_Metabolic_Process	Human	Uterus	rep_26	8.8e-08
BHMT	GOBP_Amino_Acid_Betaine_Metabolic_Process	Human	Uterus	rep_29	5.2e-08
BHMT	GOBP_Regulation_Of_Cellular_Amine_Metabolic_Process	Human	Uterus	rep_31	4.9e-06
BHMT	GOBP_Amine_Catabolic_Process	Human	Breast	rep_1	3.8e-15
BHMT	GOBP_Amine_Metabolic_Process	Human	Breast	rep_1	4.2e-96
BHMT	GOBP_Cellular_Ketone_Metabolic_Process	Human	Breast	rep_1	6.1e-19
BHMT	GOBP_Cellular_Metabolic_Compound_Salvage	Human	Breast	rep_1	4.7e-05
BHMT	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Human	Breast	rep_1	5.3e-32
BHMT	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Breast	rep_1	2.3e-10
BHMT	GOBP_Regulation_Of_Cellular_Amine_Metabolic_Process	Human	Breast	rep_1	6.5e-13
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Breast	rep_1	6.4e-19
BHMT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Breast	rep_1	2.1e-94
BHMT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
BHMT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.7e-08
BHMT	GOBP_Amino_Acid_Betaine_Metabolic_Process	Human	Breast	rep_6	2.7e-08
BHMT	GOBP_Ammonium_Ion_Metabolic_Process	Human	Breast	rep_6	2.5e-10
BHMT	GOBP_Aspartate_Family_Amino_Acid_Biosynthetic_Process	Human	Breast	rep_6	3.7e-05
BHMT	GOBP_Aspartate_Family_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	4.1e-08
BHMT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.0e-10
BHMT	GOBP_Methionine_Biosynthetic_Process	Human	Breast	rep_6	6.8e-08
BHMT	GOBP_Methylation	Human	Breast	rep_6	1.7e-06
BHMT	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
BHMT	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
BHMT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
BHMT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
BHMT	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
BHMT	GOBP_Sulfur_Amino_Acid_Biosynthetic_Process	Human	Breast	rep_6	5.2e-05
BHMT	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	2.0e-06
BHMT	GOBP_Sulfur_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
BHMT	GOBP_Sulfur_Compound_Metabolic_Process	Human	Breast	rep_6	3.0e-10
BHMT	GOBP_Ammonium_Ion_Metabolic_Process	Human	Skin	P2_rep2	9.3e-09
BHMT	GOBP_Sulfur_Amino_Acid_Metabolic_Process	Human	Skin	P2_rep2	2.4e-08
BHMT	GOBP_Aspartate_Family_Amino_Acid_Biosynthetic_Process	Human	Skin	P5_rep1	4.3e-09
BHMT	GOBP_Aspartate_Family_Amino_Acid_Metabolic_Process	Human	Skin	P5_rep1	2.3e-10
BHMT	GOBP_Sulfur_Compound_Biosynthetic_Process	Human	Skin	P5_rep1	6.9e-17
BHMT	GOBP_Amino_Acid_Salvage	Human	Skin	P5_rep2	7.1e-19
BHMT	GOBP_Amine_Catabolic_Process	Human	Skin	P10_rep1	1.5e-15
BHMT	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Human	Skin	P10_rep1	1.2e-16
BHMT	GOBP_Homocysteine_Metabolic_Process	Human	Skin	P10_rep1	4.7e-09
BHMT	GOBP_Amino_Acid_Betaine_Metabolic_Process	Human	Skin	P10_rep2	8.2e-15
BHMT	GOBP_Regulation_Of_Sulfur_Metabolic_Process	Human	Skin	P10_rep2	1.5e-10
BHMT	GOBP_Choline_Metabolic_Process	Human	Skin	P10_rep3	5.4e-10
BHMT	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Human	Lung	rep_1	1.3e-14
BHMT	GOBP_Cellular_Ketone_Metabolic_Process	Human	Lung	rep_2	2.1e-09
BHMT	GOBP_Regulation_Of_Cellular_Ketone_Metabolic_Process	Human	Lung	rep_2	2.2e-10

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BHMT function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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BHMT function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for BHMT envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for BHMT

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for BHMT

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source