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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SCP2 (spascer ID:6342)

Gene summary for SCP2

Gene summary

Gene information
	Species	Human
	Gene symbol	SCP2
	Gene ID	6342
	Gene name	sterol carrier protein 2
	Synonyms	NLTP\|NSL-TP\|SCOX\|SCP-2\|SCP-CHI\|SCP-X\|SCPX
	Cytomap	1p32.3
	Type of gene	protein-coding
	Description	sterol carrier protein 2SCP-2/3-oxoacyl-CoA thiolaseSCP-2/thiolaseacetyl-CoA C-myristoyltransferaseepididymis secretory sperm binding proteinnon-specific lipid-transfer proteinpropanoyl-CoA C-acyltransferasesterol carrier protein Xstraight-chain a
	Modification date	20220513
	UniProtAcc	P22307

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SCP2	GO:0006694	steroid biosynthetic process	21873635	Process
SCP2	GO:0015914	phospholipid transport	21873635	Process
SCP2	GO:0032385	positive regulation of intracellular cholesterol transport	21873635	Process
SCP2	GO:0032934	sterol binding	21873635	Function

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Spatial pattern events for SCP2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SCP2	Human	Liver	rep_1	34792289	4.25e-09
SCP2	Human	Intestine	rep_colon1	34417225	1.95e-15
SCP2	Human	Intestine	rep_colon2	34417225	8.12e-16
SCP2	Human	Intestine	rep_colon3	34417225	8.40e-10
SCP2	Human	Intestine	rep_colon4	34417225	1.14e-15
SCP2	Human	Liver	rep_liver1	34417225	3.57e-15
SCP2	Human	Liver	rep_liver2	34417225	6.98e-16
SCP2	Human	Liver	rep_liver3	34417225	3.51e-15
SCP2	Human	Liver	rep_liver4	34417225	7.71e-16
SCP2	Human	Intestine	A1	33406409	2.09e-15
SCP2	Human	Intestine	A2	33406409	2.47e-15
SCP2	Human	Uterus	rep_3	34857954	1.66e-15
SCP2	Human	Breast	A3	34650042	1.21e-06
SCP2	Human	Breast	A5	34650042	4.86e-08
SCP2	Human	Breast	A6	34650042	2.92e-06
SCP2	Human	Breast	C4	34650042	1.23e-08
SCP2	Human	Heart	w9_s5	31835037	1.77e-03
SCP2	Human	Lung	rep_1	35355018	4.90e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_1_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_3_H&E
Breast_A3_H&E
Breast_A5_H&E
Breast_A6_H&E
Breast_C4_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has SCP2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SCP2	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
SCP2	GOBP_Positive_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
SCP2	GOBP_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
SCP2	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Oxidase	Human	Bladder	rep_2	1.4e-05
SCP2	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
SCP2	GOBP_Positive_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
SCP2	GOBP_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
SCP2	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
SCP2	GOBP_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
SCP2	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SCP2	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SCP2	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Intestine	A3	3.8e-08
SCP2	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SCP2	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SCP2	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
SCP2	GOBP_Organic_Hydroxy_Compound_Transport	Human	Intestine	A3	7.3e-09
SCP2	GOBP_Positive_Regulation_Of_Intracellular_Transport	Human	Intestine	A3	4.0e-16
SCP2	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	A3	9.5e-08
SCP2	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
SCP2	GOBP_Protein_Targeting	Human	Intestine	A3	6.5e-09
SCP2	GOBP_Regulation_Of_Cellular_Localization	Human	Intestine	A3	4.5e-11
SCP2	GOBP_Regulation_Of_Intracellular_Transport	Human	Intestine	A3	4.4e-10
SCP2	GOBP_Regulation_Of_Transport	Human	Intestine	A3	4.4e-11
SCP2	GOBP_Alpha_Linolenic_Acid_Metabolic_Process	Human	Intestine	A8	1.8e-27
SCP2	GOBP_Bile_Acid_Biosynthetic_Process	Human	Intestine	A8	1.0e-12
SCP2	GOBP_Bile_Acid_Metabolic_Process	Human	Intestine	A8	5.1e-08
SCP2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
SCP2	GOBP_Fatty_Acid_Beta_Oxidation	Human	Intestine	A8	1.0e-13
SCP2	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Oxidase	Human	Intestine	A8	5.5e-13
SCP2	GOBP_Fatty_Acid_Catabolic_Process	Human	Intestine	A8	2.2e-14
SCP2	GOBP_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-13
SCP2	GOBP_Intracellular_Lipid_Transport	Human	Intestine	A8	8.1e-07
SCP2	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
SCP2	GOBP_Lipid_Localization	Human	Intestine	A8	2.5e-15
SCP2	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
SCP2	GOBP_Lipid_Modification	Human	Intestine	A8	2.7e-13
SCP2	GOBP_Lipid_Oxidation	Human	Intestine	A8	1.5e-15
SCP2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	8.2e-09
SCP2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Intestine	A8	1.5e-10
SCP2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
SCP2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
SCP2	GOBP_Organic_Acid_Catabolic_Process	Human	Intestine	A8	1.6e-12
SCP2	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
SCP2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Intestine	A8	1.2e-10
SCP2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
SCP2	GOBP_Organophosphate_Ester_Transport	Human	Intestine	A8	1.8e-09
SCP2	GOBP_Peroxisomal_Transport	Human	Intestine	A8	1.4e-22
SCP2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Intestine	A8	1.1e-09
SCP2	GOBP_Positive_Regulation_Of_Lipid_Localization	Human	Intestine	A8	3.5e-08
SCP2	GOBP_Positive_Regulation_Of_Lipid_Transport	Human	Intestine	A8	8.7e-07
SCP2	GOBP_Regulation_Of_Anion_Transport	Human	Intestine	A8	2.7e-14
SCP2	GOBP_Regulation_Of_Intracellular_Lipid_Transport	Human	Intestine	A8	3.1e-07
SCP2	GOBP_Regulation_Of_Ion_Transport	Human	Intestine	A8	2.0e-13
SCP2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
SCP2	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
SCP2	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
SCP2	GOBP_Steroid_Biosynthetic_Process	Human	Intestine	A8	7.2e-18
SCP2	GOBP_Steroid_Metabolic_Process	Human	Intestine	A8	7.9e-16
SCP2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	1.4e-12
SCP2	GOBP_Fatty_Acid_Beta_Oxidation	Human	Pancreas	PDAC-B-st1	5.8e-05
SCP2	GOBP_Lipid_Oxidation	Human	Pancreas	PDAC-B-st1	1.3e-06
SCP2	GOBP_Protein_Targeting	Human	Pancreas	PDAC-B-st1	9.4e-05
SCP2	GOBP_Regulation_Of_Anion_Transport	Human	Pancreas	PDAC-B-st1	4.7e-06
SCP2	GOBP_Phospholipid_Transport	Human	Pancreas	PDAC-A-st2	1.2e-08
SCP2	GOBP_Lipid_Modification	Human	Uterus	rep_1	1.8e-07
SCP2	GOBP_Olefinic_Compound_Metabolic_Process	Human	Uterus	rep_1	3.8e-07
SCP2	GOBP_Sterol_Transport	Human	Uterus	rep_1	2.9e-06
SCP2	GOBP_Positive_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	3.2e-07
SCP2	GOBP_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	1.5e-11
SCP2	GOBP_Alpha_Linolenic_Acid_Metabolic_Process	Human	Uterus	rep_26	2.7e-11
SCP2	GOBP_Bile_Acid_Metabolic_Process	Human	Uterus	rep_26	2.7e-09
SCP2	GOBP_Cellular_Lipid_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
SCP2	GOBP_Fatty_Acid_Beta_Oxidation	Human	Uterus	rep_26	6.2e-07
SCP2	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Oxidase	Human	Uterus	rep_26	1.2e-06
SCP2	GOBP_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
SCP2	GOBP_Intracellular_Lipid_Transport	Human	Uterus	rep_26	1.4e-09
SCP2	GOBP_Lipid_Localization	Human	Uterus	rep_26	3.7e-10
SCP2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.9e-09
SCP2	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	1.0e-07
SCP2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Uterus	rep_26	1.3e-10
SCP2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
SCP2	GOBP_Organic_Acid_Catabolic_Process	Human	Uterus	rep_26	6.9e-09
SCP2	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
SCP2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Uterus	rep_26	3.2e-10
SCP2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
SCP2	GOBP_Regulation_Of_Intracellular_Lipid_Transport	Human	Uterus	rep_26	2.5e-08
SCP2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
SCP2	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
SCP2	GOBP_Steroid_Biosynthetic_Process	Human	Uterus	rep_26	4.3e-06
SCP2	GOBP_Steroid_Metabolic_Process	Human	Uterus	rep_26	1.0e-07
SCP2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	3.3e-07
SCP2	GOBP_Bile_Acid_Biosynthetic_Process	Human	Uterus	rep_29	2.7e-06
SCP2	GOBP_Organic_Hydroxy_Compound_Transport	Human	Uterus	rep_29	3.2e-06
SCP2	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SCP2	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SCP2	GOBP_Intracellular_Lipid_Transport	Human	Breast	rep_1	1.2e-92
SCP2	GOBP_Intracellular_Sterol_Transport	Human	Breast	rep_1	3.7e-83
SCP2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Breast	rep_1	5.8e-04
SCP2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
SCP2	GOBP_Organic_Hydroxy_Compound_Transport	Human	Breast	rep_1	9.0e-228
SCP2	GOBP_Positive_Regulation_Of_Intracellular_Transport	Human	Breast	rep_1	1.7e-05
SCP2	GOBP_Positive_Regulation_Of_Sterol_Transport	Human	Breast	rep_1	1.2e-120
SCP2	GOBP_Positive_Regulation_Of_Transport	Human	Breast	rep_1	3.1e-10
SCP2	GOBP_Regulation_Of_Cellular_Localization	Human	Breast	rep_1	5.5e-07
SCP2	GOBP_Regulation_Of_Intracellular_Lipid_Transport	Human	Breast	rep_1	2.1e-70
SCP2	GOBP_Regulation_Of_Intracellular_Transport	Human	Breast	rep_1	4.7e-13
SCP2	GOBP_Regulation_Of_Ion_Transport	Human	Breast	rep_1	1.7e-09
SCP2	GOBP_Regulation_Of_Sterol_Transport	Human	Breast	rep_1	1.1e-07
SCP2	GOBP_Regulation_Of_Transport	Human	Breast	rep_1	3.7e-17
SCP2	GOBP_Sterol_Transport	Human	Breast	rep_1	5.3e-15
SCP2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
SCP2	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Oxidase	Human	Breast	rep_5	2.4e-06
SCP2	GOBP_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	1.2e-06
SCP2	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
SCP2	GOBP_Lipid_Localization	Human	Breast	rep_5	1.4e-06
SCP2	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
SCP2	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.9e-17
SCP2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
SCP2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Breast	rep_5	2.0e-19
SCP2	GOBP_Regulation_Of_Anion_Transport	Human	Breast	rep_5	1.6e-05
SCP2	GOBP_Regulation_Of_Lipid_Localization	Human	Breast	rep_5	1.1e-05
SCP2	GOBP_Regulation_Of_Lipid_Transport	Human	Breast	rep_5	2.0e-04
SCP2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	3.8e-09
SCP2	GOBP_Alpha_Linolenic_Acid_Metabolic_Process	Human	Breast	rep_6	3.0e-09
SCP2	GOBP_Bile_Acid_Metabolic_Process	Human	Breast	rep_6	8.3e-05
SCP2	GOBP_Cellular_Lipid_Catabolic_Process	Human	Breast	rep_6	3.6e-11
SCP2	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Breast	rep_6	8.5e-11
SCP2	GOBP_Fatty_Acid_Beta_Oxidation	Human	Breast	rep_6	7.4e-12
SCP2	GOBP_Fatty_Acid_Catabolic_Process	Human	Breast	rep_6	8.9e-13
SCP2	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SCP2	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SCP2	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
SCP2	GOBP_Lipid_Modification	Human	Breast	rep_6	8.0e-04
SCP2	GOBP_Lipid_Oxidation	Human	Breast	rep_6	2.6e-15
SCP2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Breast	rep_6	6.3e-10
SCP2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
SCP2	GOBP_Olefinic_Compound_Metabolic_Process	Human	Breast	rep_6	1.5e-08
SCP2	GOBP_Organic_Acid_Catabolic_Process	Human	Breast	rep_6	1.5e-11
SCP2	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
SCP2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Breast	rep_6	2.5e-06
SCP2	GOBP_Peroxisomal_Transport	Human	Breast	rep_6	7.7e-04
SCP2	GOBP_Peroxisome_Organization	Human	Breast	rep_6	2.2e-04
SCP2	GOBP_Positive_Regulation_Of_Anion_Transport	Human	Breast	rep_6	4.1e-08
SCP2	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
SCP2	GOBP_Protein_Targeting	Human	Breast	rep_6	5.5e-10
SCP2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
SCP2	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
SCP2	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
SCP2	GOBP_Steroid_Biosynthetic_Process	Human	Breast	rep_6	2.7e-04
SCP2	GOBP_Steroid_Metabolic_Process	Human	Breast	rep_6	6.6e-05
SCP2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Skin	P2_rep3	8.1e-08
SCP2	GOBP_Positive_Regulation_Of_Intracellular_Transport	Human	Skin	P5_rep3	1.3e-08
SCP2	GOBP_Peroxisomal_Transport	Human	Skin	P10_rep1	1.0e-11
SCP2	GOBP_Peroxisome_Organization	Human	Skin	P10_rep1	3.2e-09
SCP2	GOBP_Positive_Regulation_Of_Lipid_Localization	Human	Skin	P10_rep1	3.7e-08
SCP2	GOBP_Positive_Regulation_Of_Lipid_Transport	Human	Skin	P10_rep1	1.0e-07
SCP2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Skin	P10_rep3	8.9e-08
SCP2	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09
SCP2	GOBP_Positive_Regulation_Of_Sterol_Transport	Human	Lung	rep_2	4.0e-08
SCP2	GOBP_Regulation_Of_Lipid_Transport	Human	Lung	rep_2	7.8e-07
SCP2	GOBP_Regulation_Of_Sterol_Transport	Human	Lung	rep_2	8.4e-10

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SCP2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SCP2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SCP2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SCP2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SCP2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SCP2	C3150990	LEUKOENCEPHALOPATHY WITH DYSTONIA AND MOTOR NEUROPATHY	2	CTD_human;GENOMICS_ENGLAND;ORPHANET
SCP2	C0013421	Dystonia	1	CTD_human
SCP2	C0152025	Polyneuropathy	1	CTD_human
SCP2	C0270612	Leukoencephalopathy	1	CTD_human
SCP2	C0271683	Polyneuropathy, Motor	1	CTD_human
SCP2	C0393588	Dystonia, Paroxysmal	1	CTD_human
SCP2	C0393610	Dystonia, Diurnal	1	CTD_human
SCP2	C0393851	Polyneuropathy, Critical Illness	1	CTD_human
SCP2	C0751093	Dystonia, Limb	1	CTD_human
SCP2	C0751448	Polyneuropathy, Familial	1	CTD_human
SCP2	C0751449	Acquired Polyneuropathy	1	CTD_human
SCP2	C1858991	Childhood Ataxia with Central Nervous System Hypomyelinization	1	CTD_human