Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: VPS52 (spascer ID:6293)

Gene summary for VPS52

Gene summary

Gene information
	Species	Human
	Gene symbol	VPS52
	Gene ID	6293
	Gene name	VPS52 subunit of GARP complex
	Synonyms	ARE1\|SAC2\|SACM2L\|dJ1033B10.5
	Cytomap	6p21.32
	Type of gene	protein-coding
	Description	vacuolar protein sorting-associated protein 52 homologSAC2 suppressor of actin mutations 2-like proteinVPS52, GARP complex subunitvacuolar protein sorting 52 homolog
	Modification date	20220513
	UniProtAcc	Q8N1B4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
VPS52	GO:0000938	GARP complex	21873635	Component
VPS52	GO:0006896	Golgi to vacuole transport	21873635	Process
VPS52	GO:0007041	lysosomal transport	21873635	Process
VPS52	GO:0019905	syntaxin binding	21873635	Function
VPS52	GO:0032456	endocytic recycling	21873635	Process
VPS52	GO:0042147	retrograde transport, endosome to Golgi	21873635	Process

Top

Spatial pattern events for VPS52

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
VPS52	Human	Liver	rep_liver2	34417225	6.98e-16
VPS52	Human	Breast	B2	34650042	6.22e-09
VPS52	Human	Breast	B5	34650042	4.13e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver2_H&E
Breast_B2_H&E
Breast_B5_H&E

Top

Spatial pattern pathway has VPS52 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
VPS52	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
VPS52	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
VPS52	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
VPS52	GOBP_Cytosolic_Transport	Human	Intestine	A3	5.9e-09
VPS52	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
VPS52	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
VPS52	GOBP_Endosomal_Transport	Human	Intestine	A3	1.9e-09
VPS52	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
VPS52	GOBP_Golgi_Vesicle_Transport	Human	Intestine	A3	9.2e-10
VPS52	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
VPS52	GOBP_Lysosomal_Transport	Human	Intestine	A3	7.2e-12
VPS52	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Intestine	A3	1.9e-10
VPS52	GOBP_Retrograde_Transport_Endosome_To_Golgi	Human	Intestine	A3	1.1e-08
VPS52	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
VPS52	GOBP_Vacuolar_Transport	Human	Intestine	A3	4.3e-14
VPS52	GOBP_Ectodermal_Cell_Differentiation	Human	Intestine	A8	2.9e-23
VPS52	GOBP_Embryonic_Digestive_Tract_Development	Human	Intestine	A8	5.5e-12
VPS52	GOBP_Endocytic_Recycling	Human	Intestine	A8	4.4e-21
VPS52	GOBP_Golgi_To_Vacuole_Transport	Human	Intestine	A8	6.5e-20
VPS52	GOBP_Ectoderm_Development	Human	Pancreas	PDAC-B-st1	6.0e-05
VPS52	GOBP_Retrograde_Transport_Endosome_To_Golgi	Human	Pancreas	PDAC-B-st1	1.7e-06
VPS52	GOBP_Endosomal_Transport	Human	Pancreas	PDAC-A-st2	9.1e-05
VPS52	GOBP_Golgi_To_Vacuole_Transport	Human	Pancreas	PDAC-A-st2	4.2e-06
VPS52	GOBP_Ectoderm_Development	Human	Uterus	rep_26	3.0e-11
VPS52	GOBP_Endosomal_Transport	Human	Uterus	rep_26	1.1e-06
VPS52	GOBP_Golgi_Vesicle_Transport	Human	Uterus	rep_26	3.4e-14
VPS52	GOBP_Lysosomal_Transport	Human	Uterus	rep_26	1.3e-08
VPS52	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Uterus	rep_26	4.4e-08
VPS52	GOBP_Vacuolar_Transport	Human	Uterus	rep_26	2.2e-09
VPS52	GOBP_Ectoderm_Development	Human	Breast	rep_1	9.3e-05
VPS52	GOBP_Embryonic_Digestive_Tract_Development	Human	Breast	rep_1	1.4e-10
VPS52	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
VPS52	GOBP_Tissue_Morphogenesis	Human	Breast	rep_1	1.4e-30
VPS52	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
VPS52	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
VPS52	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
VPS52	GOBP_Endocytic_Recycling	Human	Breast	rep_5	4.1e-05
VPS52	GOBP_Golgi_To_Vacuole_Transport	Human	Breast	rep_5	1.6e-14
VPS52	GOBP_Lysosomal_Transport	Human	Breast	rep_5	9.9e-17
VPS52	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Breast	rep_5	8.2e-04
VPS52	GOBP_Vacuolar_Transport	Human	Breast	rep_5	6.0e-13
VPS52	GOBP_Cytosolic_Transport	Human	Breast	rep_6	2.6e-05
VPS52	GOBP_Endosomal_Transport	Human	Breast	rep_6	1.7e-13
VPS52	GOBP_Golgi_Vesicle_Transport	Human	Breast	rep_6	2.0e-08
VPS52	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
VPS52	GOBP_Retrograde_Transport_Endosome_To_Golgi	Human	Breast	rep_6	7.5e-05
VPS52	GOBP_Tissue_Morphogenesis	Human	Skin	P2_rep1	2.9e-08
VPS52	GOBP_Ectodermal_Cell_Differentiation	Human	Skin	P5_rep1	6.7e-16
VPS52	GOBP_Embryonic_Digestive_Tract_Development	Human	Skin	P10_rep2	2.5e-08
VPS52	GOBP_Ectoderm_Development	Human	Lung	rep_1	2.0e-08
VPS52	GOBP_Lysosomal_Transport	Human	Lung	rep_2	4.5e-09
VPS52	GOBP_Vacuolar_Transport	Human	Lung	rep_2	8.0e-08

Top

VPS52 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

VPS52 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for VPS52 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for VPS52

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for VPS52

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
VPS52	C0033578	Prostatic Neoplasms	1	CTD_human
VPS52	C0376358	Malignant neoplasm of prostate	1	CTD_human