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Spatial pattern gene: SAA4 (spascer ID:6291) |
Gene summary for SAA4 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SAA4 | Gene ID | 6291 |
| Gene name | serum amyloid A4, constitutive |
| Synonyms | C-SAA|CSAA |
| Cytomap | 11p15.1 |
| Type of gene | protein-coding |
| Description | serum amyloid A-4 proteinconstitutively expressed serum amyloid A protein |
| Modification date | 20220513 |
| UniProtAcc | P35542 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for SAA4 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SAA4 | Human | Liver | rep_1 | 34792289 | 5.95e-14 |
| SAA4 | Human | Liver | rep_liver1 | 34417225 | 1.89e-15 |
| SAA4 | Human | Liver | rep_liver2 | 34417225 | 1.27e-15 |
| SAA4 | Human | Liver | rep_liver3 | 34417225 | 3.51e-15 |
| SAA4 | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_1_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver3_H&E  |  |
Liver_rep_liver4_H&E  |  |
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Spatial pattern pathway has SAA4 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SAA4 | GOBP_Acute_Inflammatory_Response | Human | Brain | rep_4 | 5.6e-28 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Brain | rep_4 | 6.7e-28 |
| SAA4 | GOBP_Defense_Response | Human | Brain | rep_4 | 2.2e-20 |
| SAA4 | GOBP_Inflammatory_Response | Human | Brain | rep_4 | 5.6e-28 |
| SAA4 | GOBP_Acute_Inflammatory_Response | Human | Liver | rep_1 | 1.1e-67 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Liver | rep_1 | 2.9e-51 |
| SAA4 | GOBP_Defense_Response | Human | Liver | rep_1 | 1.3e-59 |
| SAA4 | GOBP_Inflammatory_Response | Human | Liver | rep_1 | 1.1e-67 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Intestine | rep_colon2 | 7.3e-11 |
| SAA4 | GOBP_Acute_Inflammatory_Response | Human | Intestine | rep_colon4 | 3.1e-51 |
| SAA4 | GOBP_Defense_Response | Human | Intestine | rep_colon4 | 2.5e-86 |
| SAA4 | GOBP_Inflammatory_Response | Human | Intestine | rep_colon4 | 3.1e-51 |
| SAA4 | GOBP_Defense_Response | Human | Intestine | A3 | 6.3e-13 |
| SAA4 | GOBP_Inflammatory_Response | Human | Intestine | A3 | 2.9e-09 |
| SAA4 | GOBP_Acute_Inflammatory_Response | Human | Intestine | A8 | 5.9e-12 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Intestine | A8 | 3.3e-07 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Uterus | rep_2 | 1.2e-09 |
| SAA4 | GOBP_Defense_Response | Human | Uterus | rep_1 | 3.0e-06 |
| SAA4 | GOBP_Acute_Inflammatory_Response | Human | Uterus | rep_28 | 6.2e-06 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Breast | rep_1 | 8.0e-41 |
| SAA4 | GOBP_Defense_Response | Human | Breast | rep_1 | 1.0e-09 |
| SAA4 | GOBP_Inflammatory_Response | Human | Breast | rep_1 | 3.7e-43 |
| SAA4 | GOBP_Acute_Phase_Response | Human | Skin | P10_rep1 | 1.9e-20 |
| SAA4 | GOBP_Defense_Response | Human | Lung | rep_1 | 9.9e-12 |
| SAA4 | GOBP_Inflammatory_Response | Human | Lung | rep_1 | 1.4e-10 |
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SAA4 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SAA4 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SAA4 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for SAA4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SAA4 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
