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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SAA1 (spascer ID:6288)

Gene summary for SAA1

Gene summary

Gene information
	Species	Human
	Gene symbol	SAA1
	Gene ID	6288
	Gene name	serum amyloid A1
	Synonyms	PIG4\|SAA\|SAA2\|TP53I4
	Cytomap	11p15.1
	Type of gene	protein-coding
	Description	serum amyloid A-1 proteinserum amyloid A proteintumor protein p53 inducible protein 4
	Modification date	20220513
	UniProtAcc	P0DJI8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for SAA1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SAA1	Human	Brain	rep_1	33558695	5.52e-15
SAA1	Human	Brain	rep_2	33558695	5.54e-15
SAA1	Human	Brain	rep_3	33558695	4.93e-15
SAA1	Human	Brain	rep_4	33558695	6.08e-15
SAA1	Human	Brain	rep_5	33558695	1.16e-14
SAA1	Human	Brain	rep_6	33558695	1.21e-14
SAA1	Human	Brain	rep_7	33558695	1.03e-14
SAA1	Human	Brain	rep_8	33558695	1.14e-14
SAA1	Human	Brain	rep_9	33558695	3.01e-15
SAA1	Human	Brain	rep_10	33558695	3.23e-15
SAA1	Human	Brain	rep_11	33558695	3.36e-15
SAA1	Human	Brain	rep_12	33558695	3.65e-15
SAA1	Human	Bladder	rep_1	34385456	8.93e-15
SAA1	Human	Liver	rep_1	34792289	2.38e-14
SAA1	Human	Intestine	rep_colon1	34417225	1.95e-15
SAA1	Human	Liver	rep_liver1	34417225	1.89e-15
SAA1	Human	Liver	rep_liver2	34417225	1.27e-15
SAA1	Human	Liver	rep_liver3	34417225	3.51e-15
SAA1	Human	Liver	rep_liver4	34417225	7.71e-16
SAA1	Human	Breast	B1	34650042	8.74e-06
SAA1	Human	Breast	B2	34650042	3.82e-13
SAA1	Human	Breast	B3	34650042	1.33e-06
SAA1	Human	Breast	B4	34650042	4.64e-12
SAA1	Human	Breast	B6	34650042	5.62e-13
SAA1	Human	Breast	E3	34650042	2.02e-12
SAA1	Human	Breast	G2	34650042	1.98e-06
SAA1	Human	Breast	H1	34650042	3.39e-14
SAA1	Human	Breast	H2	34650042	3.19e-14
SAA1	Human	Breast	H3	34650042	4.80e-14
SAA1	Human	Breast	1142243F	34493872	2.30e-15
SAA1	Human	Breast	1160920F	34493872	1.48e-15
SAA1	Human	Breast	CID4465	34493872	4.85e-15
SAA1	Human	Breast	CID44971	34493872	1.76e-15
SAA1	Human	Breast	CID4535	34493872	6.37e-15
SAA1	Human	Lung	rep_1	35355018	4.99e-15
SAA1	Human	Lung	rep_2	35355018	2.37e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_7_H&E
Brain_rep_8_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Bladder_rep_1_H&E
Liver_rep_1_H&E
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Breast_B1_H&E
Breast_B2_H&E
Breast_B3_H&E
Breast_B4_H&E
Breast_B6_H&E
Breast_E3_H&E
Breast_G2_H&E
Breast_H1_H&E
Breast_H2_H&E
Breast_H3_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has SAA1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SAA1	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
SAA1	GOBP_Endocytosis	Human	Brain	rep_1	7.4e-34
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Brain	rep_1	2.8e-23
SAA1	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
SAA1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
SAA1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	3.1e-68
SAA1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
SAA1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
SAA1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	2.8e-23
SAA1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
SAA1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
SAA1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	2.8e-23
SAA1	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Brain	rep_1	6.9e-125
SAA1	GOBP_Regulation_Of_Defense_Response	Human	Brain	rep_1	3.1e-41
SAA1	GOBP_Regulation_Of_Inflammatory_Response	Human	Brain	rep_1	3.1e-41
SAA1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	1.2e-64
SAA1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
SAA1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
SAA1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	7.4e-34
SAA1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Brain	rep_1	4.6e-05
SAA1	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
SAA1	GOBP_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
SAA1	GOBP_Response_To_Wounding	Human	Brain	rep_1	6.9e-125
SAA1	GOBP_Taxis	Human	Brain	rep_1	2.3e-68
SAA1	GOBP_Wound_Healing	Human	Brain	rep_1	6.9e-125
SAA1	GOBP_Acute_Inflammatory_Response	Human	Brain	rep_4	5.6e-28
SAA1	GOBP_Acute_Phase_Response	Human	Brain	rep_4	6.7e-28
SAA1	GOBP_Cytokine_Production	Human	Brain	rep_4	4.1e-17
SAA1	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
SAA1	GOBP_Inflammatory_Response	Human	Brain	rep_4	5.6e-28
SAA1	GOBP_Innate_Immune_Response	Human	Brain	rep_4	1.2e-64
SAA1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Brain	rep_4	4.1e-17
SAA1	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
SAA1	GOBP_Platelet_Activation	Human	Bladder	rep_2	1.2e-05
SAA1	GOBP_Wound_Healing	Human	Bladder	rep_2	4.6e-05
SAA1	GOBP_Acute_Inflammatory_Response	Human	Liver	rep_1	1.1e-67
SAA1	GOBP_Acute_Phase_Response	Human	Liver	rep_1	2.9e-51
SAA1	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
SAA1	GOBP_Cytokine_Production	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
SAA1	GOBP_Endocytosis	Human	Liver	rep_1	1.5e-73
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Inflammatory_Response	Human	Liver	rep_1	1.1e-67
SAA1	GOBP_Innate_Immune_Response	Human	Liver	rep_1	7.3e-68
SAA1	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
SAA1	GOBP_Negative_Regulation_Of_Response_To_External_Stimulus	Human	Liver	rep_1	2.8e-53
SAA1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Liver	rep_1	2.8e-53
SAA1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
SAA1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Liver	rep_1	6.0e-76
SAA1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
SAA1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
SAA1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
SAA1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
SAA1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Liver	rep_1	3.1e-62
SAA1	GOBP_Regulation_Of_Defense_Response	Human	Liver	rep_1	3.7e-85
SAA1	GOBP_Regulation_Of_Inflammatory_Response	Human	Liver	rep_1	3.7e-85
SAA1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
SAA1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
SAA1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
SAA1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Liver	rep_1	5.3e-67
SAA1	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
SAA1	GOBP_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
SAA1	GOBP_Response_To_Wounding	Human	Liver	rep_1	3.1e-62
SAA1	GOBP_Taxis	Human	Liver	rep_1	8.8e-90
SAA1	GOBP_Wound_Healing	Human	Liver	rep_1	3.1e-62
SAA1	GOBP_Acute_Phase_Response	Human	Intestine	rep_colon2	7.3e-11
SAA1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	3.4e-10
SAA1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	rep_colon2	3.9e-21
SAA1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	2.4e-25
SAA1	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
SAA1	GOBP_Response_To_Wounding	Human	Intestine	rep_colon2	3.9e-21
SAA1	GOBP_Taxis	Human	Intestine	rep_colon2	5.0e-29
SAA1	GOBP_Wound_Healing	Human	Intestine	rep_colon2	3.9e-21
SAA1	GOBP_Acute_Inflammatory_Response	Human	Intestine	rep_colon4	3.1e-51
SAA1	GOBP_Cytokine_Production	Human	Intestine	rep_colon4	9.0e-12
SAA1	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
SAA1	GOBP_Inflammatory_Response	Human	Intestine	rep_colon4	3.1e-51
SAA1	GOBP_Innate_Immune_Response	Human	Intestine	rep_colon4	3.4e-69
SAA1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	rep_colon4	1.9e-09
SAA1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
SAA1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
SAA1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
SAA1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
SAA1	GOBP_Regulation_Of_Defense_Response	Human	Intestine	rep_colon4	5.8e-33
SAA1	GOBP_Regulation_Of_Inflammatory_Response	Human	Intestine	rep_colon4	5.8e-33
SAA1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	rep_colon4	2.2e-52
SAA1	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
SAA1	GOBP_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
SAA1	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
SAA1	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
SAA1	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
SAA1	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
SAA1	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
SAA1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Intestine	A3	2.6e-09
SAA1	GOBP_Cytokine_Production	Human	Intestine	A3	8.9e-12
SAA1	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
SAA1	GOBP_Endocytosis	Human	Intestine	A3	9.3e-10
SAA1	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SAA1	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
SAA1	GOBP_Inflammatory_Response	Human	Intestine	A3	2.9e-09
SAA1	GOBP_Leukocyte_Migration	Human	Intestine	A3	1.5e-08
SAA1	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
SAA1	GOBP_Mapk_Cascade	Human	Intestine	A3	1.1e-12
SAA1	GOBP_Myeloid_Leukocyte_Migration	Human	Intestine	A3	1.3e-07
SAA1	GOBP_Negative_Regulation_Of_Inflammatory_Response	Human	Intestine	A3	3.0e-07
SAA1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Intestine	A3	6.0e-11
SAA1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
SAA1	GOBP_Positive_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	4.4e-10
SAA1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	A3	8.0e-16
SAA1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
SAA1	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Intestine	A3	1.7e-08
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	2.6e-10
SAA1	GOBP_Positive_Regulation_Of_Map_Kinase_Activity	Human	Intestine	A3	4.4e-09
SAA1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
SAA1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
SAA1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	7.8e-15
SAA1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
SAA1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
SAA1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	2.0e-08
SAA1	GOBP_Positive_Regulation_Of_Protein_Serine_Threonine_Kinase_Activity	Human	Intestine	A3	5.6e-07
SAA1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
SAA1	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	A3	2.9e-09
SAA1	GOBP_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	1.5e-10
SAA1	GOBP_Regulation_Of_Cytosolic_Calcium_Ion_Concentration	Human	Intestine	A3	1.2e-08
SAA1	GOBP_Regulation_Of_Defense_Response	Human	Intestine	A3	1.6e-08
SAA1	GOBP_Regulation_Of_Inflammatory_Response	Human	Intestine	A3	1.8e-11
SAA1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	7.5e-12
SAA1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
SAA1	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
SAA1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
SAA1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	8.8e-11
SAA1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	A3	1.0e-09
SAA1	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
SAA1	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
SAA1	GOBP_Regulation_Of_Transport	Human	Intestine	A3	4.4e-11
SAA1	GOBP_Secretion	Human	Intestine	A3	1.8e-13
SAA1	GOBP_Taxis	Human	Intestine	A3	5.0e-08
SAA1	GOBP_Acute_Inflammatory_Response	Human	Intestine	A8	5.9e-12
SAA1	GOBP_Acute_Phase_Response	Human	Intestine	A8	3.3e-07
SAA1	GOBP_Cellular_Homeostasis	Human	Intestine	A8	2.1e-11
SAA1	GOBP_Cellular_Ion_Homeostasis	Human	Intestine	A8	4.3e-12
SAA1	GOBP_Chemical_Homeostasis	Human	Intestine	A8	1.3e-12
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
SAA1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Intestine	A8	1.0e-12
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Intestine	A8	1.4e-14
SAA1	GOBP_Granulocyte_Chemotaxis	Human	Intestine	A8	8.1e-13
SAA1	GOBP_Granulocyte_Migration	Human	Intestine	A8	1.6e-12
SAA1	GOBP_Interleukin_1_Production	Human	Intestine	A8	4.5e-17
SAA1	GOBP_Ion_Homeostasis	Human	Intestine	A8	6.1e-15
SAA1	GOBP_Leukocyte_Chemotaxis	Human	Intestine	A8	3.7e-14
SAA1	GOBP_Lymphocyte_Migration	Human	Intestine	A8	1.8e-13
SAA1	GOBP_Macrophage_Chemotaxis	Human	Intestine	A8	9.7e-18
SAA1	GOBP_Macrophage_Migration	Human	Intestine	A8	8.3e-14
SAA1	GOBP_Metal_Ion_Homeostasis	Human	Intestine	A8	2.2e-10
SAA1	GOBP_Mononuclear_Cell_Migration	Human	Intestine	A8	4.0e-13
SAA1	GOBP_Negative_Regulation_Of_Defense_Response	Human	Intestine	A8	8.0e-16
SAA1	GOBP_Negative_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	A8	3.0e-16
SAA1	GOBP_Neutrophil_Chemotaxis	Human	Intestine	A8	8.9e-16
SAA1	GOBP_Neutrophil_Migration	Human	Intestine	A8	5.8e-10
SAA1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Intestine	A8	1.1e-12
SAA1	GOBP_Receptor_Mediated_Endocytosis	Human	Intestine	A8	6.9e-09
SAA1	GOBP_Regulation_Of_Anion_Transport	Human	Intestine	A8	2.7e-14
SAA1	GOBP_Regulation_Of_Ion_Transport	Human	Intestine	A8	2.0e-13
SAA1	GOBP_Regulation_Of_Map_Kinase_Activity	Human	Intestine	A8	8.8e-11
SAA1	GOBP_Regulation_Of_Peptide_Transport	Human	Intestine	A8	1.3e-14
SAA1	GOBP_Regulation_Of_Secretion	Human	Intestine	A8	2.2e-15
SAA1	GOBP_Response_To_Cytokine	Human	Intestine	A8	1.6e-08
SAA1	GOBP_Macrophage_Migration	Human	Pancreas	PDAC-B-st1	3.4e-05
SAA1	GOBP_Positive_Regulation_Of_Map_Kinase_Activity	Human	Pancreas	PDAC-B-st1	9.1e-07
SAA1	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Pancreas	PDAC-B-st1	1.1e-05
SAA1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.9e-05
SAA1	GOBP_Regulation_Of_Anion_Transport	Human	Pancreas	PDAC-B-st1	4.7e-06
SAA1	GOBP_Lymphocyte_Chemotaxis	Human	Pancreas	PDAC-A-st2	1.9e-05
SAA1	GOBP_Acute_Phase_Response	Human	Uterus	rep_2	1.2e-09
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
SAA1	GOBP_Innate_Immune_Response	Human	Uterus	rep_4	6.1e-31
SAA1	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
SAA1	GOBP_Macrophage_Chemotaxis	Human	Uterus	rep_1	1.3e-07
SAA1	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Uterus	rep_25	7.3e-15
SAA1	GOBP_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	1.5e-11
SAA1	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Uterus	rep_26	2.8e-13
SAA1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Uterus	rep_26	2.0e-10
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Uterus	rep_26	3.5e-06
SAA1	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
SAA1	GOBP_Interleukin_1_Production	Human	Uterus	rep_26	4.3e-08
SAA1	GOBP_Macrophage_Migration	Human	Uterus	rep_26	4.9e-06
SAA1	GOBP_Platelet_Activation	Human	Uterus	rep_26	2.9e-08
SAA1	GOBP_Receptor_Mediated_Endocytosis	Human	Uterus	rep_26	5.3e-09
SAA1	GOBP_Regulation_Of_Secretion	Human	Uterus	rep_26	1.7e-06
SAA1	GOBP_Acute_Inflammatory_Response	Human	Uterus	rep_28	6.2e-06
SAA1	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
SAA1	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
SAA1	GOBP_Leukocyte_Migration	Human	Uterus	rep_29	1.5e-07
SAA1	GOBP_Lymphocyte_Migration	Human	Uterus	rep_29	2.0e-09
SAA1	GOBP_Mononuclear_Cell_Migration	Human	Uterus	rep_29	3.4e-06
SAA1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Uterus	rep_29	1.2e-06
SAA1	GOBP_Neutrophil_Migration	Human	Uterus	rep_29	1.3e-06
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Uterus	rep_29	5.5e-06
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Uterus	rep_29	1.7e-06
SAA1	GOBP_Regulation_Of_Cytosolic_Calcium_Ion_Concentration	Human	Uterus	rep_29	4.5e-07
SAA1	GOBP_Regulation_Of_Peptide_Transport	Human	Uterus	rep_29	1.2e-06
SAA1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
SAA1	GOBP_Acute_Phase_Response	Human	Breast	rep_1	8.0e-41
SAA1	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
SAA1	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
SAA1	GOBP_Cellular_Homeostasis	Human	Breast	rep_1	2.8e-10
SAA1	GOBP_Cellular_Ion_Homeostasis	Human	Breast	rep_1	7.6e-24
SAA1	GOBP_Chemical_Homeostasis	Human	Breast	rep_1	4.8e-18
SAA1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Breast	rep_1	1.5e-144
SAA1	GOBP_Cytokine_Production	Human	Breast	rep_1	6.5e-12
SAA1	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
SAA1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Breast	rep_1	1.2e-25
SAA1	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Breast	rep_1	3.6e-09
SAA1	GOBP_Granulocyte_Chemotaxis	Human	Breast	rep_1	3.7e-93
SAA1	GOBP_Granulocyte_Migration	Human	Breast	rep_1	3.5e-61
SAA1	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
SAA1	GOBP_Inflammatory_Response	Human	Breast	rep_1	3.7e-43
SAA1	GOBP_Interleukin_1_Production	Human	Breast	rep_1	1.2e-35
SAA1	GOBP_Ion_Homeostasis	Human	Breast	rep_1	1.4e-53
SAA1	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
SAA1	GOBP_Lymphocyte_Chemotaxis	Human	Breast	rep_1	8.0e-138
SAA1	GOBP_Lymphocyte_Migration	Human	Breast	rep_1	4.7e-116
SAA1	GOBP_Metal_Ion_Homeostasis	Human	Breast	rep_1	6.8e-70
SAA1	GOBP_Mononuclear_Cell_Migration	Human	Breast	rep_1	1.5e-05
SAA1	GOBP_Negative_Regulation_Of_Response_To_External_Stimulus	Human	Breast	rep_1	1.6e-04
SAA1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Breast	rep_1	2.4e-07
SAA1	GOBP_Neutrophil_Chemotaxis	Human	Breast	rep_1	4.8e-37
SAA1	GOBP_Neutrophil_Migration	Human	Breast	rep_1	9.3e-15
SAA1	GOBP_Platelet_Activation	Human	Breast	rep_1	5.9e-157
SAA1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Breast	rep_1	6.5e-10
SAA1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
SAA1	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Breast	rep_1	6.2e-26
SAA1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
SAA1	GOBP_Receptor_Mediated_Endocytosis	Human	Breast	rep_1	2.7e-84
SAA1	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Breast	rep_1	3.7e-127
SAA1	GOBP_Regulation_Of_Cell_Adhesion	Human	Breast	rep_1	1.7e-16
SAA1	GOBP_Regulation_Of_Cytosolic_Calcium_Ion_Concentration	Human	Breast	rep_1	2.9e-140
SAA1	GOBP_Regulation_Of_Defense_Response	Human	Breast	rep_1	1.1e-15
SAA1	GOBP_Regulation_Of_Inflammatory_Response	Human	Breast	rep_1	7.3e-22
SAA1	GOBP_Regulation_Of_Ion_Transport	Human	Breast	rep_1	1.7e-09
SAA1	GOBP_Regulation_Of_Peptide_Transport	Human	Breast	rep_1	7.5e-04
SAA1	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
SAA1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Breast	rep_1	2.9e-17
SAA1	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
SAA1	GOBP_Regulation_Of_Secretion	Human	Breast	rep_1	1.1e-10
SAA1	GOBP_Regulation_Of_Transport	Human	Breast	rep_1	3.7e-17
SAA1	GOBP_Response_To_Cytokine	Human	Breast	rep_1	2.5e-24
SAA1	GOBP_Response_To_Wounding	Human	Breast	rep_1	4.7e-165
SAA1	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
SAA1	GOBP_Wound_Healing	Human	Breast	rep_1	5.3e-150
SAA1	GOBP_Cell_Chemotaxis	Human	Breast	rep_5	5.7e-10
SAA1	GOBP_Leukocyte_Chemotaxis	Human	Breast	rep_5	5.0e-12
SAA1	GOBP_Leukocyte_Migration	Human	Breast	rep_5	6.0e-14
SAA1	GOBP_Mapk_Cascade	Human	Breast	rep_5	4.6e-17
SAA1	GOBP_Myeloid_Leukocyte_Migration	Human	Breast	rep_5	2.3e-11
SAA1	GOBP_Negative_Regulation_Of_Inflammatory_Response	Human	Breast	rep_5	5.7e-07
SAA1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
SAA1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	5.3e-08
SAA1	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Breast	rep_5	1.9e-16
SAA1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
SAA1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	5.9e-12
SAA1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
SAA1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
SAA1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	1.0e-15
SAA1	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
SAA1	GOBP_Regulation_Of_Anion_Transport	Human	Breast	rep_5	1.6e-05
SAA1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	8.7e-11
SAA1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
SAA1	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_5	1.4e-06
SAA1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
SAA1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	5.8e-14
SAA1	GOBP_Regulation_Of_Protein_Serine_Threonine_Kinase_Activity	Human	Breast	rep_5	1.7e-10
SAA1	GOBP_Taxis	Human	Breast	rep_5	1.2e-12
SAA1	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.8e-04
SAA1	GOBP_Positive_Regulation_Of_Map_Kinase_Activity	Human	Breast	rep_6	1.9e-05
SAA1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.5e-05
SAA1	GOBP_Positive_Regulation_Of_Protein_Serine_Threonine_Kinase_Activity	Human	Breast	rep_6	5.3e-05
SAA1	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
SAA1	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
SAA1	GOBP_Taxis	Human	Skin	P2_rep2	1.2e-08
SAA1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Skin	P2_rep3	1.3e-08
SAA1	GOBP_Acute_Phase_Response	Human	Skin	P10_rep1	1.9e-20
SAA1	GOBP_Macrophage_Migration	Human	Skin	P10_rep3	1.2e-09
SAA1	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
SAA1	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
SAA1	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
SAA1	GOBP_Inflammatory_Response	Human	Lung	rep_1	1.4e-10
SAA1	GOBP_Ion_Homeostasis	Human	Lung	rep_1	6.1e-07
SAA1	GOBP_Mononuclear_Cell_Migration	Human	Lung	rep_1	2.0e-11
SAA1	GOBP_Negative_Regulation_Of_Response_To_External_Stimulus	Human	Lung	rep_1	3.5e-09
SAA1	GOBP_Neutrophil_Migration	Human	Lung	rep_1	1.0e-07
SAA1	GOBP_Platelet_Activation	Human	Lung	rep_1	4.2e-10
SAA1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	7.4e-09
SAA1	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	3.2e-09
SAA1	GOBP_Regulation_Of_Protein_Serine_Threonine_Kinase_Activity	Human	Lung	rep_1	9.4e-09
SAA1	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
SAA1	GOBP_Cellular_Homeostasis	Human	Lung	rep_2	7.3e-07
SAA1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Lung	rep_2	4.8e-08
SAA1	GOBP_Granulocyte_Chemotaxis	Human	Lung	rep_2	6.1e-07
SAA1	GOBP_Granulocyte_Migration	Human	Lung	rep_2	2.1e-07
SAA1	GOBP_Regulation_Of_Peptide_Transport	Human	Lung	rep_2	2.6e-07
SAA1	GOBP_Regulation_Of_Secretion	Human	Lung	rep_2	9.3e-09
SAA1	GOBP_Taxis	Human	Lung	rep_2	4.0e-07

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SAA1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SAA1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
SAA1	FPR2	SAA1_FPR2	Brain	rep_10
SAA1	FPR1	SAA1_FPR1	Brain	rep_10
SAA1	TLR2	SAA1_TLR2	Brain	rep_10
SAA1	SCARB1	SAA1_SCARB1	Brain	rep_10
SAA1	ADRA2A	SAA1_ADRA2A	Brain	rep_10
SAA1	MTNR1A	SAA1_MTNR1A	Brain	rep_10
SAA1	GRM7	SAA1_GRM7	Brain	rep_10
SAA1	FPR2	SAA1_FPR2	Breast	B2
SAA1	FPR1	SAA1_FPR1	Breast	B2
SAA1	TLR2	SAA1_TLR2	Breast	B2
SAA1	SCARB1	SAA1_SCARB1	Breast	B2
SAA1	ADRA2A	SAA1_ADRA2A	Breast	B2
SAA1	MTNR1A	SAA1_MTNR1A	Breast	B2
SAA1	GRM7	SAA1_GRM7	Breast	B2

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Transcription factor for SAA1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SAA1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SAA1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SAA1	C0221014	Reactive systemic amyloidosis	4	ORPHANET
SAA1	C0003865	Arthritis, Adjuvant-Induced	1	CTD_human
SAA1	C0011616	Contact Dermatitis	1	CTD_human
SAA1	C0162351	Contact hypersensitivity	1	CTD_human
SAA1	C0971858	Arthritis, Collagen-Induced	1	CTD_human
SAA1	C0993582	Arthritis, Experimental	1	CTD_human