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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: S100A13 (spascer ID:6284)

Gene summary for S100A13

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

S100A13

Gene ID

6284

Gene nameS100 calcium binding protein A13
Synonyms-
Cytomap1q21.3
Type of geneprotein-coding
Descriptionprotein S100-A13
Modification date20220513
UniProtAcc

Q99584


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
S100A13

GO:0005509

calcium ion binding

21873635

Function
S100A13

GO:0005615

extracellular space

21873635

Component
S100A13

GO:0008284

positive regulation of cell population proliferation

21873635

Process
S100A13

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

21873635

Process
S100A13

GO:0048306

calcium-dependent protein binding

21873635

Function
S100A13

GO:0048471

perinuclear region of cytoplasm

21873635

Component
S100A13

GO:0050786

RAGE receptor binding

21873635

Function

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Spatial pattern events for S100A13

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
S100A13HumanBrainrep_1 335586955.52e-15
S100A13HumanBrainrep_2 335586955.54e-15
S100A13HumanBrainrep_3 335586954.93e-15
S100A13HumanBrainrep_4 335586956.08e-15
S100A13HumanBrainrep_7 335586952.01e-13
S100A13HumanBrainrep_8 335586951.15e-13
S100A13HumanBrainrep_9 335586953.01e-15
S100A13HumanBrainrep_10 335586953.23e-15
S100A13HumanBrainrep_11 335586953.36e-15
S100A13HumanBrainrep_12 335586953.65e-15
S100A13HumanBladderrep_1 343854561.68e-09
S100A13HumanIntestinerep_colon1 344172253.42e-15
S100A13HumanIntestinerep_colon2 344172258.12e-16
S100A13HumanIntestinerep_colon3 344172251.01e-15
S100A13HumanIntestinerep_colon4 344172251.14e-15
S100A13HumanLiverrep_liver1 344172251.08e-15
S100A13HumanLiverrep_liver2 344172256.98e-16
S100A13HumanLiverrep_liver3 344172253.51e-15
S100A13HumanLiverrep_liver4 344172257.71e-16
S100A13HumanIntestineA1 334064092.09e-15
S100A13HumanIntestineA2 334064092.47e-15
S100A13HumanIntestineA4 334064095.58e-10
S100A13HumanPancreasPDAC-A-st1 319327304.39e-09
S100A13HumanUterusrep_1 348579545.13e-15
S100A13HumanUterusrep_2 348579542.55e-15
S100A13HumanUterusrep_3 348579541.66e-15
S100A13HumanUterusrep_4 348579541.82e-15
S100A13HumanBreast1142243F 344938723.10e-11
S100A13HumanBreast1160920F 344938721.48e-15
S100A13HumanBreastCID4290 344938724.68e-15
S100A13HumanBreastCID4465 344938724.85e-15
S100A13HumanBreastCID44971 344938721.76e-15
S100A13HumanSkinP2_rep1 329467851.04e-13
S100A13HumanSkinP2_rep2 329467855.16e-12
S100A13HumanSkinP2_rep3 329467855.83e-09
S100A13HumanLungrep_1 353550181.37e-14

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_7_H&E
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Brain_rep_8_H&E
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Brain_rep_9_H&E
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Brain_rep_10_H&E
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Brain_rep_11_H&E
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Brain_rep_12_H&E
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Bladder_rep_1_H&E
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Intestine_rep_colon1_H&E
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Intestine_rep_colon2_H&E
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Intestine_rep_colon3_H&E
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Intestine_rep_colon4_H&E
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Liver_rep_liver1_H&E
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Liver_rep_liver2_H&E
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Liver_rep_liver3_H&E
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Liver_rep_liver4_H&E
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Intestine_A1_H&E
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Intestine_A2_H&E
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Intestine_A4_H&E
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Uterus_rep_1_H&E
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Uterus_rep_2_H&E
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Uterus_rep_3_H&E
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Uterus_rep_4_H&E
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Breast_1142243F_H&E
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Breast_1160920F_H&E
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Breast_CID4290_H&E
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Breast_CID4465_H&E
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Breast_CID44971_H&E
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Skin_P2_rep3_H&E
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Lung_rep_1_H&E
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Spatial pattern pathway has S100A13 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
S100A13GOBP_Immune_Effector_ProcessHumanBrainrep_1 8.1e-16
S100A13GOBP_Leukocyte_Mediated_ImmunityHumanBrainrep_1 8.1e-16
S100A13GOBP_Myeloid_Leukocyte_Mediated_ImmunityHumanBrainrep_1 2.8e-23
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanBrainrep_1 1.3e-60
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanBrainrep_1 3.1e-68
S100A13GOBP_Positive_Regulation_Of_SignalingHumanBrainrep_1 6.4e-05
S100A13GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanBrainrep_1 1.2e-64
S100A13GOBP_Cell_MorphogenesisHumanBrainrep_4 1.0e-14
S100A13GOBP_Cytokine_ProductionHumanBrainrep_4 4.1e-17
S100A13GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanBrainrep_4 4.1e-17
S100A13GOBP_Interleukin_1_Alpha_ProductionHumanBladderrep_2 2.5e-09
S100A13GOBP_Cell_MorphogenesisHumanLiverrep_1 2.1e-52
S100A13GOBP_Cytokine_ProductionHumanLiverrep_1 1.0e-70
S100A13GOBP_Immune_Effector_ProcessHumanLiverrep_1 9.0e-62
S100A13GOBP_Leukocyte_Mediated_ImmunityHumanLiverrep_1 9.0e-62
S100A13GOBP_Myeloid_Leukocyte_Mediated_ImmunityHumanLiverrep_1 1.0e-70
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanLiverrep_1 2.0e-49
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanLiverrep_1 6.9e-47
S100A13GOBP_Positive_Regulation_Of_SignalingHumanLiverrep_1 2.9e-73
S100A13GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanLiverrep_1 1.0e-70
S100A13GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanLiverrep_1 6.9e-47
S100A13GOBP_Cell_MorphogenesisHumanIntestinerep_colon2 1.5e-57
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanIntestinerep_colon2 2.9e-50
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanIntestinerep_colon2 3.4e-10
S100A13GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanIntestinerep_colon2 2.4e-25
S100A13GOBP_Cytokine_ProductionHumanIntestinerep_colon4 9.0e-12
S100A13GOBP_Immune_Effector_ProcessHumanIntestinerep_colon4 1.3e-27
S100A13GOBP_Leukocyte_Mediated_ImmunityHumanIntestinerep_colon4 1.3e-27
S100A13GOBP_Positive_Regulation_Of_SignalingHumanIntestinerep_colon4 2.0e-10
S100A13GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanIntestinerep_colon4 9.0e-12
S100A13GOBP_Cell_ActivationHumanIntestineA3 6.2e-08
S100A13GOBP_Cell_Activation_Involved_In_Immune_ResponseHumanIntestineA3 4.0e-14
S100A13GOBP_Cell_MorphogenesisHumanIntestineA3 9.7e-08
S100A13GOBP_Cytokine_ProductionHumanIntestineA3 8.9e-12
S100A13GOBP_Establishment_Of_Organelle_LocalizationHumanIntestineA3 9.7e-13
S100A13GOBP_Establishment_Of_Protein_LocalizationHumanIntestineA3 5.0e-10
S100A13GOBP_ExocytosisHumanIntestineA3 4.7e-10
S100A13GOBP_Immune_Effector_ProcessHumanIntestineA3 3.9e-14
S100A13GOBP_Leukocyte_Mediated_ImmunityHumanIntestineA3 8.2e-10
S100A13GOBP_Organelle_LocalizationHumanIntestineA3 5.1e-12
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanIntestineA3 3.5e-07
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanIntestineA3 2.6e-10
S100A13GOBP_Positive_Regulation_Of_SignalingHumanIntestineA3 3.3e-14
S100A13GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanIntestineA3 4.8e-12
S100A13GOBP_Regulation_Of_Cell_MorphogenesisHumanIntestineA3 5.8e-11
S100A13GOBP_Regulation_Of_Cell_ShapeHumanIntestineA3 3.3e-10
S100A13GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanIntestineA3 7.5e-12
S100A13GOBP_Response_To_Abiotic_StimulusHumanIntestineA3 5.3e-18
S100A13GOBP_Response_To_Electrical_StimulusHumanIntestineA3 4.8e-24
S100A13GOBP_Response_To_Inorganic_SubstanceHumanIntestineA3 6.8e-07
S100A13GOBP_SecretionHumanIntestineA3 1.8e-13
S100A13GOBP_Interleukin_1_ProductionHumanIntestineA8 4.5e-17
S100A13GOBP_Myeloid_Leukocyte_ActivationHumanIntestineA8 3.8e-18
S100A13GOBP_Myeloid_Leukocyte_Mediated_ImmunityHumanIntestineA8 8.5e-11
S100A13GOBP_Response_To_Copper_IonHumanIntestineA8 2.5e-12
S100A13GOBP_Response_To_Metal_IonHumanIntestineA8 2.1e-21
S100A13GOBP_Cell_Activation_Involved_In_Immune_ResponseHumanPancreasPDAC-B-st1 1.2e-05
S100A13GOBP_Response_To_Electrical_StimulusHumanPancreasPDAC-B-st1 1.0e-05
S100A13GOBP_Mast_Cell_Activation_Involved_In_Immune_ResponseHumanPancreasPDAC-A-st2 2.4e-06
S100A13GOBP_Interleukin_1_Alpha_ProductionHumanPancreasPDAC-A-st3 2.0e-05
S100A13GOBP_Immune_Effector_ProcessHumanUterusrep_4 2.0e-31
S100A13GOBP_Leukocyte_Mediated_ImmunityHumanUterusrep_4 2.0e-31
S100A13GOBP_Response_To_Copper_IonHumanUterusrep_25 6.9e-12
S100A13GOBP_Cell_Activation_Involved_In_Immune_ResponseHumanUterusrep_26 1.5e-11
S100A13GOBP_ExocytosisHumanUterusrep_26 5.1e-10
S100A13GOBP_Interleukin_1_Alpha_ProductionHumanUterusrep_26 1.3e-14
S100A13GOBP_Interleukin_1_ProductionHumanUterusrep_26 4.3e-08
S100A13GOBP_Mast_Cell_ActivationHumanUterusrep_26 7.0e-12
S100A13GOBP_Mast_Cell_Activation_Involved_In_Immune_ResponseHumanUterusrep_26 2.6e-11
S100A13GOBP_Myeloid_Leukocyte_ActivationHumanUterusrep_26 1.4e-11
S100A13GOBP_Response_To_Electrical_StimulusHumanUterusrep_26 3.6e-08
S100A13GOBP_Cell_ActivationHumanUterusrep_28 2.5e-06
S100A13GOBP_Myeloid_Leukocyte_Mediated_ImmunityHumanUterusrep_28 8.7e-06
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanUterusrep_29 5.5e-06
S100A13GOBP_Cell_MorphogenesisHumanBreastrep_1 5.7e-26
S100A13GOBP_Cytokine_ProductionHumanBreastrep_1 6.5e-12
S100A13GOBP_Establishment_Of_Organelle_LocalizationHumanBreastrep_1 6.5e-08
S100A13GOBP_Establishment_Of_Protein_LocalizationHumanBreastrep_1 7.2e-05
S100A13GOBP_ExocytosisHumanBreastrep_1 2.8e-29
S100A13GOBP_I_Kappab_Kinase_Nf_Kappab_SignalingHumanBreastrep_1 1.2e-47
S100A13GOBP_Interleukin_1_ProductionHumanBreastrep_1 1.2e-35
S100A13GOBP_Mast_Cell_ActivationHumanBreastrep_1 1.1e-08
S100A13GOBP_Mast_Cell_Activation_Involved_In_Immune_ResponseHumanBreastrep_16.4e-155
S100A13GOBP_Myeloid_Leukocyte_ActivationHumanBreastrep_1 2.2e-37
S100A13GOBP_Organelle_LocalizationHumanBreastrep_1 1.8e-08
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanBreastrep_1 9.2e-11
S100A13GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_SignalingHumanBreastrep_1 2.0e-36
S100A13GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanBreastrep_1 4.6e-22
S100A13GOBP_Regulation_Of_Cell_MorphogenesisHumanBreastrep_1 5.0e-35
S100A13GOBP_Regulation_Of_Cell_ShapeHumanBreastrep_1 3.2e-94
S100A13GOBP_Response_To_Abiotic_StimulusHumanBreastrep_1 2.6e-19
S100A13GOBP_Response_To_Electrical_StimulusHumanBreastrep_1 1.2e-51
S100A13GOBP_Response_To_Metal_IonHumanBreastrep_1 3.0e-20
S100A13GOBP_SecretionHumanBreastrep_1 9.7e-57
S100A13GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionHumanBreastrep_5 5.3e-08
S100A13GOBP_Positive_Regulation_Of_SignalingHumanBreastrep_5 1.3e-06
S100A13GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanBreastrep_5 8.7e-11
S100A13GOBP_Response_To_Copper_IonHumanBreastrep_5 3.0e-06
S100A13GOBP_Response_To_Inorganic_SubstanceHumanBreastrep_5 1.8e-10
S100A13GOBP_Organelle_LocalizationHumanSkinP5_rep1 2.1e-13
S100A13GOBP_Response_To_Electrical_StimulusHumanSkinP10_rep1 2.2e-10
S100A13GOBP_Interleukin_1_Alpha_ProductionHumanSkinP10_rep2 2.7e-14
S100A13GOBP_Myeloid_Leukocyte_Mediated_ImmunityHumanSkinP10_rep2 1.1e-22
S100A13GOBP_Cell_ActivationHumanLungrep_1 2.1e-08
S100A13GOBP_Interleukin_1_Alpha_ProductionHumanLungrep_1 9.0e-12
S100A13GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanLungrep_1 7.3e-07
S100A13GOBP_Cell_Activation_Involved_In_Immune_ResponseHumanLungrep_2 8.0e-10
S100A13GOBP_I_Kappab_Kinase_Nf_Kappab_SignalingHumanLungrep_2 6.0e-08
S100A13GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_SignalingHumanLungrep_2 2.5e-08

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S100A13 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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S100A13 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for S100A13 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for S100A13

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
S100A13Q99584DB00768OlopatadineProtein S100-A13 SmallMoleculeDrugapproved
S100A13Q99584DB01164Calcium chlorideProtein S100-A13 SmallMoleculeDrugapproved
S100A13Q99584DB11348Calcium PhosphateProtein S100-A13 SmallMoleculeDrugapproved
S100A13Q99584DB14481Calcium phosphate dihydrateProtein S100-A13 SmallMoleculeDrugapproved
S100A13Q99584DB11093Calcium citrateProtein S100-A13 SmallMoleculeDrugapproved|investigational
S100A13Q99584DB01025AmlexanoxProtein S100-A13 SmallMoleculeDrugapproved|investigational|withdrawn

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Related Diseases for S100A13

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource