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Spatial pattern gene: S100A11 (spascer ID:6282) |
Gene summary for S100A11 |
Gene summary |
| Gene information | |
| Species | Human | Gene symbol | S100A11 | Gene ID | 6282 |
| Gene name | S100 calcium binding protein A11 |
| Synonyms | HEL-S-43|MLN70|S100C |
| Cytomap | 1q21.3 |
| Type of gene | protein-coding |
| Description | protein S100-A11MLN 70calgizzarinepididymis secretory protein Li 43metastatic lymph node gene 70 proteinprotein S100-C |
| Modification date | 20220513 |
| UniProtAcc | P31949 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| S100A11 | GO:0005509 | calcium ion binding | 21873635 | Function |
| S100A11 | GO:0005615 | extracellular space | 21873635 | Component |
| S100A11 | GO:0005737 | cytoplasm | 21873635 | Component |
| S100A11 | GO:0044548 | S100 protein binding | 21873635 | Function |
| S100A11 | GO:0048306 | calcium-dependent protein binding | 21873635 | Function |
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Spatial pattern events for S100A11 |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| S100A11 | Human | Brain | rep_1 | 33558695 | 5.52e-15 |
| S100A11 | Human | Brain | rep_2 | 33558695 | 5.54e-15 |
| S100A11 | Human | Brain | rep_3 | 33558695 | 4.93e-15 |
| S100A11 | Human | Brain | rep_4 | 33558695 | 6.08e-15 |
| S100A11 | Human | Brain | rep_5 | 33558695 | 1.16e-14 |
| S100A11 | Human | Brain | rep_6 | 33558695 | 1.21e-14 |
| S100A11 | Human | Brain | rep_7 | 33558695 | 1.03e-14 |
| S100A11 | Human | Brain | rep_8 | 33558695 | 1.14e-14 |
| S100A11 | Human | Brain | rep_9 | 33558695 | 3.01e-15 |
| S100A11 | Human | Brain | rep_10 | 33558695 | 3.23e-15 |
| S100A11 | Human | Brain | rep_11 | 33558695 | 3.36e-15 |
| S100A11 | Human | Brain | rep_12 | 33558695 | 3.65e-15 |
| S100A11 | Human | Prostate | rep_7 | 29925878 | 1.06e-14 |
| S100A11 | Human | Prostate | rep_11 | 29925878 | 1.65e-06 |
| S100A11 | Human | Bladder | rep_1 | 34385456 | 8.93e-15 |
| S100A11 | Human | Bladder | rep_2 | 34385456 | 8.28e-09 |
| S100A11 | Human | Bladder | rep_3 | 34385456 | 3.31e-12 |
| S100A11 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| S100A11 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| S100A11 | Human | Intestine | rep_colon3 | 34417225 | 1.01e-15 |
| S100A11 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| S100A11 | Human | Liver | rep_liver1 | 34417225 | 1.89e-15 |
| S100A11 | Human | Liver | rep_liver2 | 34417225 | 1.27e-15 |
| S100A11 | Human | Liver | rep_liver3 | 34417225 | 3.51e-15 |
| S100A11 | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| S100A11 | Human | Intestine | A1 | 33406409 | 3.49e-15 |
| S100A11 | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| S100A11 | Human | Pancreas | PDAC-A-st1 | 31932730 | 1.11e-14 |
| S100A11 | Human | Uterus | rep_1 | 34857954 | 5.13e-15 |
| S100A11 | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| S100A11 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| S100A11 | Human | Uterus | rep_4 | 34857954 | 1.82e-15 |
| S100A11 | Human | Breast | B1 | 34650042 | 5.06e-07 |
| S100A11 | Human | Breast | B2 | 34650042 | 5.16e-10 |
| S100A11 | Human | Breast | B6 | 34650042 | 3.71e-07 |
| S100A11 | Human | Breast | C6 | 34650042 | 5.84e-08 |
| S100A11 | Human | Breast | D2 | 34650042 | 3.17e-07 |
| S100A11 | Human | Breast | D3 | 34650042 | 8.56e-08 |
| S100A11 | Human | Breast | D4 | 34650042 | 1.06e-09 |
| S100A11 | Human | Breast | D5 | 34650042 | 1.33e-09 |
| S100A11 | Human | Breast | D6 | 34650042 | 7.92e-08 |
| S100A11 | Human | Breast | E1 | 34650042 | 1.81e-14 |
| S100A11 | Human | Breast | E2 | 34650042 | 2.12e-14 |
| S100A11 | Human | Breast | E3 | 34650042 | 1.82e-14 |
| S100A11 | Human | Breast | F2 | 34650042 | 2.36e-13 |
| S100A11 | Human | Breast | G1 | 34650042 | 1.71e-13 |
| S100A11 | Human | Breast | G2 | 34650042 | 1.86e-07 |
| S100A11 | Human | Breast | G3 | 34650042 | 2.68e-07 |
| S100A11 | Human | Breast | H1 | 34650042 | 7.72e-10 |
| S100A11 | Human | Breast | H2 | 34650042 | 1.21e-07 |
| S100A11 | Human | Breast | H3 | 34650042 | 2.34e-09 |
| S100A11 | Human | Breast | 1142243F | 34493872 | 2.30e-15 |
| S100A11 | Human | Breast | 1160920F | 34493872 | 1.48e-15 |
| S100A11 | Human | Breast | CID4290 | 34493872 | 4.68e-15 |
| S100A11 | Human | Breast | CID4465 | 34493872 | 4.85e-15 |
| S100A11 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| S100A11 | Human | Breast | CID4535 | 34493872 | 6.37e-15 |
| S100A11 | Human | Heart | w6_s2 | 31835037 | 1.67e-03 |
| S100A11 | Human | Heart | w6_s3 | 31835037 | 2.67e-12 |
| S100A11 | Human | Heart | w6_s4 | 31835037 | 1.77e-13 |
| S100A11 | Human | Heart | w6_s5 | 31835037 | 8.17e-08 |
| S100A11 | Human | Heart | w6_s6 | 31835037 | 5.49e-05 |
| S100A11 | Human | Heart | w6_s8 | 31835037 | 2.62e-05 |
| S100A11 | Human | Heart | w9_s1 | 31835037 | 9.72e-12 |
| S100A11 | Human | Heart | w9_s2 | 31835037 | 1.33e-09 |
| S100A11 | Human | Heart | w9_s3 | 31835037 | 1.64e-09 |
| S100A11 | Human | Heart | w9_s4 | 31835037 | 1.13e-06 |
| S100A11 | Human | Heart | w9_s5 | 31835037 | 2.40e-14 |
| S100A11 | Human | Heart | w9_s6 | 31835037 | 9.05e-14 |
| S100A11 | Human | Skin | P2_rep1 | 32946785 | 5.41e-15 |
| S100A11 | Human | Skin | P2_rep2 | 32946785 | 5.48e-15 |
| S100A11 | Human | Skin | P2_rep3 | 32946785 | 5.90e-15 |
| S100A11 | Human | Skin | P5_rep2 | 32946785 | 3.70e-07 |
| S100A11 | Human | Skin | P10_rep1 | 32946785 | 8.74e-08 |
| S100A11 | Human | Skin | mel2_rep1 | 30154148 | 1.95e-07 |
| S100A11 | Human | Skin | mel2_rep2 | 30154148 | 7.07e-08 |
| S100A11 | Human | Lung | rep_1 | 35355018 | 4.99e-15 |
| S100A11 | Human | Lung | rep_2 | 35355018 | 7.95e-08 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has S100A11 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| S100A11 | GOBP_Cell_Migration | Human | Brain | rep_1 | 3.1e-68 |
| S100A11 | GOBP_Immune_Effector_Process | Human | Brain | rep_1 | 8.1e-16 |
| S100A11 | GOBP_Leukocyte_Mediated_Immunity | Human | Brain | rep_1 | 8.1e-16 |
| S100A11 | GOBP_Locomotion | Human | Brain | rep_1 | 3.1e-68 |
| S100A11 | GOBP_Myeloid_Leukocyte_Mediated_Immunity | Human | Brain | rep_1 | 2.8e-23 |
| S100A11 | GOBP_Positive_Regulation_Of_Locomotion | Human | Brain | rep_1 | 3.1e-68 |
| S100A11 | GOBP_Regulation_Of_Cellular_Component_Movement | Human | Brain | rep_1 | 3.1e-68 |
| S100A11 | GOBP_Cell_Migration | Human | Liver | rep_1 | 1.9e-71 |
| S100A11 | GOBP_Immune_Effector_Process | Human | Liver | rep_1 | 9.0e-62 |
| S100A11 | GOBP_Leukocyte_Mediated_Immunity | Human | Liver | rep_1 | 9.0e-62 |
| S100A11 | GOBP_Locomotion | Human | Liver | rep_1 | 1.9e-71 |
| S100A11 | GOBP_Myeloid_Leukocyte_Mediated_Immunity | Human | Liver | rep_1 | 1.0e-70 |
| S100A11 | GOBP_Positive_Regulation_Of_Locomotion | Human | Liver | rep_1 | 1.9e-71 |
| S100A11 | GOBP_Regulation_Of_Cellular_Component_Movement | Human | Liver | rep_1 | 1.9e-71 |
| S100A11 | GOBP_Immune_Effector_Process | Human | Intestine | rep_colon4 | 1.3e-27 |
| S100A11 | GOBP_Leukocyte_Mediated_Immunity | Human | Intestine | rep_colon4 | 1.3e-27 |
| S100A11 | GOBP_Cell_Migration | Human | Intestine | rep_liver2 | 1.0e-64 |
| S100A11 | GOBP_Locomotion | Human | Intestine | rep_liver2 | 1.0e-64 |
| S100A11 | GOBP_Positive_Regulation_Of_Locomotion | Human | Intestine | rep_liver2 | 1.0e-64 |
| S100A11 | GOBP_Regulation_Of_Cellular_Component_Movement | Human | Intestine | rep_liver2 | 1.0e-64 |
| S100A11 | GOBP_Biological_Adhesion | Human | Intestine | A3 | 6.7e-11 |
| S100A11 | GOBP_Cell_Activation | Human | Intestine | A3 | 6.2e-08 |
| S100A11 | GOBP_Cell_Activation_Involved_In_Immune_Response | Human | Intestine | A3 | 4.0e-14 |
| S100A11 | GOBP_Cell_Cell_Adhesion | Human | Intestine | A3 | 2.5e-07 |
| S100A11 | GOBP_Cell_Migration | Human | Intestine | A3 | 1.6e-10 |
| S100A11 | GOBP_Dna_Replication | Human | Intestine | A3 | 2.5e-08 |
| S100A11 | GOBP_Exocytosis | Human | Intestine | A3 | 4.7e-10 |
| S100A11 | GOBP_Immune_Effector_Process | Human | Intestine | A3 | 3.9e-14 |
| S100A11 | GOBP_Leukocyte_Mediated_Immunity | Human | Intestine | A3 | 8.2e-10 |
| S100A11 | GOBP_Locomotion | Human | Intestine | A3 | 1.9e-08 |
| S100A11 | GOBP_Muscle_Cell_Migration | Human | Intestine | A3 | 2.2e-10 |
| S100A11 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Intestine | A3 | 5.9e-17 |
| S100A11 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Human | Intestine | A3 | 5.4e-19 |
| S100A11 | GOBP_Positive_Regulation_Of_Smooth_Muscle_Cell_Migration | Human | Intestine | A3 | 1.7e-07 |
| S100A11 | GOBP_Regulation_Of_Cellular_Component_Movement | Human | Intestine | A3 | 1.1e-09 |
| S100A11 | GOBP_Regulation_Of_Dna_Replication | Human | Intestine | A3 | 2.9e-12 |
| S100A11 | GOBP_Secretion | Human | Intestine | A3 | 1.8e-13 |
| S100A11 | GOBP_Smooth_Muscle_Cell_Migration | Human | Intestine | A3 | 3.2e-14 |
| S100A11 | GOBP_Myeloid_Leukocyte_Activation | Human | Intestine | A8 | 3.8e-18 |
| S100A11 | GOBP_Myeloid_Leukocyte_Mediated_Immunity | Human | Intestine | A8 | 8.5e-11 |
| S100A11 | GOBP_Negative_Regulation_Of_Dna_Replication | Human | Intestine | A8 | 6.0e-12 |
| S100A11 | GOBP_Positive_Regulation_Of_Locomotion | Human | Intestine | A8 | 9.7e-07 |
| S100A11 | GOBP_Negative_Regulation_Of_Dna_Replication | Human | Pancreas | PDAC-A-st1 | 8.3e-05 |
| S100A11 | GOBP_Cell_Activation_Involved_In_Immune_Response | Human | Pancreas | PDAC-B-st1 | 1.2e-05 |
| S100A11 | GOBP_Immune_Effector_Process | Human | Uterus | rep_4 | 2.0e-31 |
| S100A11 | GOBP_Leukocyte_Mediated_Immunity | Human | Uterus | rep_4 | 2.0e-31 |
| S100A11 | GOBP_Cell_Activation_Involved_In_Immune_Response | Human | Uterus | rep_26 | 1.5e-11 |
| S100A11 | GOBP_Dna_Replication | Human | Uterus | rep_26 | 1.5e-09 |
| S100A11 | GOBP_Exocytosis | Human | Uterus | rep_26 | 5.1e-10 |
| S100A11 | GOBP_Myeloid_Leukocyte_Activation | Human | Uterus | rep_26 | 1.4e-11 |
| S100A11 | GOBP_Negative_Regulation_Of_Dna_Replication | Human | Uterus | rep_26 | 6.3e-07 |
| S100A11 | GOBP_Positive_Regulation_Of_Smooth_Muscle_Cell_Migration | Human | Uterus | rep_26 | 5.7e-10 |
| S100A11 | GOBP_Regulation_Of_Dna_Replication | Human | Uterus | rep_26 | 1.5e-08 |
| S100A11 | GOBP_Cell_Activation | Human | Uterus | rep_28 | 2.5e-06 |
| S100A11 | GOBP_Myeloid_Leukocyte_Mediated_Immunity | Human | Uterus | rep_28 | 8.7e-06 |
| S100A11 | GOBP_Biological_Adhesion | Human | Uterus | rep_29 | 3.3e-06 |
| S100A11 | GOBP_Biological_Adhesion | Human | Breast | rep_1 | 4.0e-110 |
| S100A11 | GOBP_Cell_Cell_Adhesion | Human | Breast | rep_1 | 3.6e-45 |
| S100A11 | GOBP_Cell_Migration | Human | Breast | rep_1 | 1.5e-45 |
| S100A11 | GOBP_Exocytosis | Human | Breast | rep_1 | 2.8e-29 |
| S100A11 | GOBP_Locomotion | Human | Breast | rep_1 | 4.5e-54 |
| S100A11 | GOBP_Muscle_Cell_Migration | Human | Breast | rep_1 | 4.6e-157 |
| S100A11 | GOBP_Myeloid_Leukocyte_Activation | Human | Breast | rep_1 | 2.2e-37 |
| S100A11 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Human | Breast | rep_1 | 1.3e-54 |
| S100A11 | GOBP_Negative_Regulation_Of_Dna_Replication | Human | Breast | rep_1 | 5.9e-34 |
| S100A11 | GOBP_Positive_Regulation_Of_Locomotion | Human | Breast | rep_1 | 7.2e-115 |
| S100A11 | GOBP_Positive_Regulation_Of_Smooth_Muscle_Cell_Migration | Human | Breast | rep_1 | 3.1e-91 |
| S100A11 | GOBP_Regulation_Of_Cellular_Component_Movement | Human | Breast | rep_1 | 5.5e-21 |
| S100A11 | GOBP_Secretion | Human | Breast | rep_1 | 9.7e-57 |
| S100A11 | GOBP_Smooth_Muscle_Cell_Migration | Human | Breast | rep_1 | 6.9e-206 |
| S100A11 | GOBP_Dna_Replication | Human | Breast | rep_6 | 3.5e-07 |
| S100A11 | GOBP_Negative_Regulation_Of_Biosynthetic_Process | Human | Breast | rep_6 | 2.6e-08 |
| S100A11 | GOBP_Regulation_Of_Dna_Replication | Human | Breast | rep_6 | 1.8e-08 |
| S100A11 | GOBP_Negative_Regulation_Of_Dna_Replication | Human | Skin | P10_rep1 | 8.8e-08 |
| S100A11 | GOBP_Myeloid_Leukocyte_Mediated_Immunity | Human | Skin | P10_rep2 | 1.1e-22 |
| S100A11 | GOBP_Cell_Activation | Human | Lung | rep_1 | 2.1e-08 |
| S100A11 | GOBP_Biological_Adhesion | Human | Lung | rep_2 | 6.6e-07 |
| S100A11 | GOBP_Cell_Activation_Involved_In_Immune_Response | Human | Lung | rep_2 | 8.0e-10 |
| S100A11 | GOBP_Cell_Cell_Adhesion | Human | Lung | rep_2 | 5.3e-07 |
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S100A11 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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S100A11 function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for S100A11 envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for S100A11 |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for S100A11 |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |