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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CLIP1 (spascer ID:6249)

Gene summary for CLIP1

Gene summary

Gene information
	Species	Human
	Gene symbol	CLIP1
	Gene ID	6249
	Gene name	CAP-Gly domain containing linker protein 1
	Synonyms	CLIP\|CLIP-170\|CLIP170\|CYLN1\|RSN
	Cytomap	12q24.31
	Type of gene	protein-coding
	Description	CAP-Gly domain-containing linker protein 1cytoplasmic linker protein 1cytoplasmic linker protein 170 alpha-2cytoplasmic linker protein CLIP-170restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
	Modification date	20220513
	UniProtAcc	P30622

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CLIP1	GO:0005634	nucleus	21873635	Component
CLIP1	GO:0005737	cytoplasm	21873635	Component
CLIP1	GO:0031116	positive regulation of microtubule polymerization	21873635	Process
CLIP1	GO:0031122	cytoplasmic microtubule organization	21873635	Process
CLIP1	GO:0051010	microtubule plus-end binding	21873635	Function

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Spatial pattern events for CLIP1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CLIP1	Human	Intestine	rep_colon2	34417225	8.12e-16
CLIP1	Human	Intestine	rep_colon3	34417225	4.41e-14
CLIP1	Human	Intestine	rep_colon4	34417225	2.57e-08
CLIP1	Human	Liver	rep_liver1	34417225	3.46e-10
CLIP1	Human	Liver	rep_liver2	34417225	3.44e-08
CLIP1	Human	Uterus	rep_2	34857954	1.25e-11
CLIP1	Human	Breast	CID4290	34493872	8.54e-07
CLIP1	Human	Skin	P2_rep3	32946785	6.66e-07
CLIP1	Human	Skin	P5_rep1	32946785	1.32e-14
CLIP1	Human	Skin	P5_rep2	32946785	9.66e-15
CLIP1	Human	Skin	P9_rep1	32946785	1.11e-06
CLIP1	Human	Skin	P9_rep2	32946785	1.33e-10
CLIP1	Human	Skin	P10_rep3	32946785	1.37e-13

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_2_H&E
Breast_CID4290_H&E
Skin_P2_rep3_H&E
Skin_P5_rep1_H&E
Skin_P5_rep2_H&E
Skin_P9_rep1_H&E
Skin_P9_rep2_H&E
Skin_P10_rep3_H&E

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Spatial pattern pathway has CLIP1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CLIP1	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
CLIP1	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
CLIP1	GOBP_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	4.8e-11
CLIP1	GOBP_Microtubule_Polymerization	Human	Intestine	A3	1.0e-18
CLIP1	GOBP_Microtubule_Polymerization_Or_Depolymerization	Human	Intestine	A3	8.8e-18
CLIP1	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
CLIP1	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	1.9e-13
CLIP1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
CLIP1	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Human	Intestine	A3	3.4e-13
CLIP1	GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Intestine	A3	3.7e-19
CLIP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
CLIP1	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Intestine	A3	2.7e-15
CLIP1	GOBP_Positive_Regulation_Of_Protein_Polymerization	Human	Intestine	A3	1.6e-14
CLIP1	GOBP_Protein_Polymerization	Human	Intestine	A3	2.3e-10
CLIP1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
CLIP1	GOBP_Regulation_Of_Cytoskeleton_Organization	Human	Intestine	A3	6.4e-13
CLIP1	GOBP_Regulation_Of_Microtubule_Based_Process	Human	Intestine	A3	1.2e-12
CLIP1	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	2.3e-15
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization	Human	Intestine	A3	6.2e-17
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Intestine	A3	3.7e-16
CLIP1	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
CLIP1	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Intestine	A3	7.4e-11
CLIP1	GOBP_Regulation_Of_Protein_Polymerization	Human	Intestine	A3	2.5e-10
CLIP1	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Human	Intestine	A3	9.3e-07
CLIP1	GOBP_Microtubule_Bundle_Formation	Human	Pancreas	PDAC-A-st2	1.4e-06
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization	Human	Uterus	rep_25	2.7e-09
CLIP1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Uterus	rep_26	7.5e-09
CLIP1	GOBP_Microtubule_Bundle_Formation	Human	Uterus	rep_26	6.3e-10
CLIP1	GOBP_Microtubule_Polymerization	Human	Uterus	rep_26	3.7e-12
CLIP1	GOBP_Microtubule_Polymerization_Or_Depolymerization	Human	Uterus	rep_26	8.0e-10
CLIP1	GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Uterus	rep_26	1.2e-07
CLIP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
CLIP1	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Human	Uterus	rep_26	1.4e-06
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Uterus	rep_26	3.6e-08
CLIP1	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Uterus	rep_26	9.2e-07
CLIP1	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
CLIP1	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	3.5e-04
CLIP1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
CLIP1	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Human	Breast	rep_1	7.1e-32
CLIP1	GOBP_Protein_Polymerization	Human	Breast	rep_1	6.4e-28
CLIP1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
CLIP1	GOBP_Regulation_Of_Cytoskeleton_Organization	Human	Breast	rep_1	7.8e-76
CLIP1	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
CLIP1	GOBP_Regulation_Of_Protein_Polymerization	Human	Breast	rep_1	3.1e-31
CLIP1	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Human	Breast	rep_1	5.0e-50
CLIP1	GOBP_Supramolecular_Fiber_Organization	Human	Breast	rep_1	2.8e-72
CLIP1	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
CLIP1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Breast	rep_6	2.7e-05
CLIP1	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
CLIP1	GOBP_Microtubule_Bundle_Formation	Human	Breast	rep_6	5.0e-04
CLIP1	GOBP_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.9e-04
CLIP1	GOBP_Microtubule_Polymerization	Human	Breast	rep_6	2.9e-04
CLIP1	GOBP_Microtubule_Polymerization_Or_Depolymerization	Human	Breast	rep_6	6.1e-05
CLIP1	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
CLIP1	GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Breast	rep_6	7.3e-08
CLIP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
CLIP1	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Breast	rep_6	3.1e-06
CLIP1	GOBP_Positive_Regulation_Of_Protein_Polymerization	Human	Breast	rep_6	3.7e-05
CLIP1	GOBP_Regulation_Of_Microtubule_Based_Process	Human	Breast	rep_6	2.1e-05
CLIP1	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.8e-05
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization	Human	Breast	rep_6	1.1e-05
CLIP1	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Human	Breast	rep_6	2.0e-05
CLIP1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Skin	P5_rep1	3.9e-11
CLIP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
CLIP1	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12

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CLIP1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CLIP1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CLIP1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CLIP1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CLIP1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source