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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: BCS1L (spascer ID:617)

Gene summary for BCS1L

Gene summary

Gene information
	Species	Human
	Gene symbol	BCS1L
	Gene ID	617
	Gene name	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
	Synonyms	BCS\|BCS1\|BJS\|FLNMS\|GRACILE\|Hs.6719\|MC3DN1\|PTD\|h-BCS\|h-BCS1
	Cytomap	2q35
	Type of gene	protein-coding
	Description	mitochondrial chaperone BCS1BC1 (ubiquinol-cytochrome c reductase) synthesis-likeBCS1-like proteinmitochondrial complex III assembly
	Modification date	20220513
	UniProtAcc	Q9Y276

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
BCS1L	GO:0005743	mitochondrial inner membrane	21873635	Component
BCS1L	GO:0032979	protein insertion into mitochondrial inner membrane from matrix	21873635	Process
BCS1L	GO:0034551	mitochondrial respiratory chain complex III assembly	21873635	Process

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Spatial pattern events for BCS1L

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
BCS1L	Human	Intestine	rep_colon4	34417225	2.16e-13
BCS1L	Human	Liver	rep_liver1	34417225	4.21e-06
BCS1L	Human	Liver	rep_liver2	34417225	6.98e-16
BCS1L	Human	Intestine	A2	33406409	5.70e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Intestine_A2_H&E

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Spatial pattern pathway has BCS1L envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
BCS1L	GOBP_Cytochrome_Complex_Assembly	Human	Bladder	rep_4	6.0e-26
BCS1L	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Bladder	rep_4	1.8e-09
BCS1L	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Bladder	rep_4	1.1e-14
BCS1L	GOBP_Respiratory_Chain_Complex_Iv_Assembly	Human	Bladder	rep_4	4.0e-22
BCS1L	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
BCS1L	GOBP_Cytochrome_Complex_Assembly	Human	Intestine	A3	3.5e-09
BCS1L	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Intestine	A3	7.6e-11
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Intestine	A3	3.8e-08
BCS1L	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
BCS1L	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
BCS1L	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
BCS1L	GOBP_Mitochondrial_Membrane_Organization	Human	Intestine	A3	1.0e-17
BCS1L	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Intestine	A3	1.5e-07
BCS1L	GOBP_Mitochondrial_Transport	Human	Intestine	A3	9.8e-16
BCS1L	GOBP_Mitochondrion_Organization	Human	Intestine	A3	2.3e-19
BCS1L	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Intestine	A3	3.9e-07
BCS1L	GOBP_Protein_Insertion_Into_Membrane	Human	Intestine	A3	2.2e-07
BCS1L	GOBP_Protein_Localization_To_Mitochondrion	Human	Intestine	A3	3.0e-13
BCS1L	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
BCS1L	GOBP_Respiratory_Chain_Complex_Iv_Assembly	Human	Intestine	A3	9.2e-08
BCS1L	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Pancreas	PDAC-B-st1	9.9e-05
BCS1L	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Pancreas	PDAC-B-st1	4.6e-05
BCS1L	GOBP_Protein_Insertion_Into_Membrane	Human	Uterus	rep_1	7.9e-06
BCS1L	GOBP_Mitochondrial_Cytochrome_C_Oxidase_Assembly	Human	Uterus	rep_25	9.6e-09
BCS1L	GOBP_Respiratory_Chain_Complex_Iv_Assembly	Human	Uterus	rep_25	1.7e-10
BCS1L	GOBP_Mitochondrial_Membrane_Organization	Human	Uterus	rep_26	1.5e-06
BCS1L	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Uterus	rep_26	2.3e-06
BCS1L	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Uterus	rep_26	9.9e-07
BCS1L	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
BCS1L	GOBP_Cytochrome_Complex_Assembly	Human	Breast	rep_1	1.3e-184
BCS1L	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
BCS1L	GOBP_Respiratory_Chain_Complex_Iv_Assembly	Human	Breast	rep_1	3.1e-179
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Breast	rep_6	3.8e-07
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Mitochondrial_Membrane	Human	Breast	rep_6	1.0e-10
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Breast	rep_6	8.5e-11
BCS1L	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
BCS1L	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
BCS1L	GOBP_Mitochondrial_Cytochrome_C_Oxidase_Assembly	Human	Breast	rep_6	2.7e-05
BCS1L	GOBP_Mitochondrial_Membrane_Organization	Human	Breast	rep_6	3.7e-05
BCS1L	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Breast	rep_6	3.3e-04
BCS1L	GOBP_Mitochondrial_Transport	Human	Breast	rep_6	6.5e-10
BCS1L	GOBP_Mitochondrion_Organization	Human	Breast	rep_6	2.0e-05
BCS1L	GOBP_Protein_Insertion_Into_Membrane	Human	Breast	rep_6	7.3e-08
BCS1L	GOBP_Protein_Localization_To_Mitochondrion	Human	Breast	rep_6	7.1e-06
BCS1L	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
BCS1L	GOBP_Mitochondrial_Cytochrome_C_Oxidase_Assembly	Human	Skin	P5_rep1	1.8e-09
BCS1L	GOBP_Mitochondrial_Membrane_Organization	Human	Skin	P5_rep3	2.4e-11
BCS1L	GOBP_Respiratory_Chain_Complex_Iv_Assembly	Human	Skin	P9_rep2	7.3e-09
BCS1L	GOBP_Cytochrome_Complex_Assembly	Human	Skin	P10_rep1	2.7e-21
BCS1L	GOBP_Establishment_Of_Protein_Localization_To_Mitochondrial_Membrane	Human	Skin	P10_rep2	9.9e-17

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BCS1L function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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BCS1L function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for BCS1L envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for BCS1L

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for BCS1L

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source