Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: WDR48 (spascer ID:57599)

Gene summary for WDR48

Gene summary

Gene information
	Species	Human
	Gene symbol	WDR48
	Gene ID	57599
	Gene name	WD repeat domain 48
	Synonyms	Bun62\|P80\|SPG60\|UAF1
	Cytomap	3p22.2
	Type of gene	protein-coding
	Description	WD repeat-containing protein 48USP1 associated factor 1WD repeat endosomal proteintesticular tissue protein Li 224
	Modification date	20220513
	UniProtAcc	Q8TAF3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
WDR48	GO:0000724	double-strand break repair via homologous recombination	21873635	Process
WDR48	GO:0016579	protein deubiquitination	21873635	Process
WDR48	GO:0043130	ubiquitin binding	21873635	Function

Top

Spatial pattern events for WDR48

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
WDR48	Human	Liver	rep_liver1	34417225	3.27e-10
WDR48	Human	Liver	rep_liver2	34417225	6.98e-16
WDR48	Human	Uterus	rep_2	34857954	8.10e-07
WDR48	Human	Uterus	rep_3	34857954	5.81e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E

Top

Spatial pattern pathway has WDR48 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
WDR48	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
WDR48	GOBP_Positive_Regulation_Of_Proteolysis	Human	Brain	rep_1	1.2e-161
WDR48	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Brain	rep_1	4.4e-07
WDR48	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
WDR48	GOBP_Growth	Human	Brain	rep_4	1.0e-14
WDR48	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
WDR48	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
WDR48	GOBP_Skeletal_System_Development	Human	Bladder	rep_2	2.5e-15
WDR48	GOBP_Skeletal_System_Morphogenesis	Human	Bladder	rep_2	7.5e-11
WDR48	GOBP_Skin_Development	Human	Bladder	rep_2	4.8e-19
WDR48	GOBP_Growth	Human	Liver	rep_1	2.1e-52
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
WDR48	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
WDR48	GOBP_Positive_Regulation_Of_Proteolysis	Human	Liver	rep_1	2.0e-70
WDR48	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
WDR48	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.1e-67
WDR48	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
WDR48	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
WDR48	GOBP_Growth	Human	Intestine	rep_colon2	1.5e-57
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
WDR48	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	rep_colon2	1.6e-21
WDR48	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
WDR48	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Intestine	rep_colon4	1.2e-51
WDR48	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
WDR48	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
WDR48	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
WDR48	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
WDR48	GOBP_Development_Of_Primary_Sexual_Characteristics	Human	Intestine	A3	5.0e-13
WDR48	GOBP_Developmental_Growth	Human	Intestine	A3	7.3e-10
WDR48	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Intestine	A3	2.7e-15
WDR48	GOBP_Dna_Metabolic_Process	Human	Intestine	A3	1.2e-09
WDR48	GOBP_Dna_Repair	Human	Intestine	A3	4.4e-09
WDR48	GOBP_Double_Strand_Break_Repair	Human	Intestine	A3	3.1e-09
WDR48	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
WDR48	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
WDR48	GOBP_Fertilization	Human	Intestine	A3	1.8e-11
WDR48	GOBP_Gamete_Generation	Human	Intestine	A3	4.2e-13
WDR48	GOBP_Growth	Human	Intestine	A3	3.3e-16
WDR48	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Intestine	A3	7.2e-10
WDR48	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
WDR48	GOBP_Male_Gamete_Generation	Human	Intestine	A3	4.8e-15
WDR48	GOBP_Male_Sex_Differentiation	Human	Intestine	A3	2.6e-16
WDR48	GOBP_Multicellular_Organism_Reproduction	Human	Intestine	A3	4.1e-15
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
WDR48	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	3.1e-07
WDR48	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Human	Intestine	A3	3.2e-09
WDR48	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
WDR48	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	4.9e-09
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
WDR48	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	A3	5.2e-21
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
WDR48	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
WDR48	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
WDR48	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	2.8e-10
WDR48	GOBP_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	3.0e-12
WDR48	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
WDR48	GOBP_Regulation_Of_Protein_Monoubiquitination	Human	Intestine	A3	8.2e-11
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Intestine	A3	9.5e-13
WDR48	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	1.1e-13
WDR48	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
WDR48	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
WDR48	GOBP_Reproductive_System_Development	Human	Intestine	A3	2.9e-14
WDR48	GOBP_Seminiferous_Tubule_Development	Human	Intestine	A3	4.1e-16
WDR48	GOBP_Sex_Differentiation	Human	Intestine	A3	6.1e-18
WDR48	GOBP_Single_Fertilization	Human	Intestine	A3	2.8e-12
WDR48	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
WDR48	GOBP_Detection_Of_Stimulus	Human	Intestine	A8	2.4e-11
WDR48	GOBP_Epithelial_Cell_Proliferation	Human	Intestine	A8	1.6e-09
WDR48	GOBP_Interstrand_Cross_Link_Repair	Human	Intestine	A8	1.9e-20
WDR48	GOBP_Positive_Regulation_Of_Protein_Deubiquitination	Human	Intestine	A8	8.5e-10
WDR48	GOBP_Protein_Monoubiquitination	Human	Intestine	A8	9.4e-12
WDR48	GOBP_Regulation_Of_Protein_Deubiquitination	Human	Intestine	A8	1.8e-10
WDR48	GOBP_Interstrand_Cross_Link_Repair	Human	Pancreas	PDAC-A-st2	1.6e-06
WDR48	GOBP_Positive_Regulation_Of_Protein_Deubiquitination	Human	Pancreas	PDAC-A-st2	6.3e-05
WDR48	GOBP_Protein_Modification_By_Small_Protein_Removal	Human	Pancreas	PDAC-A-st2	1.0e-05
WDR48	GOBP_Regulation_Of_Protein_Deubiquitination	Human	Pancreas	PDAC-A-st3	6.2e-05
WDR48	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Uterus	rep_1	1.6e-06
WDR48	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
WDR48	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
WDR48	GOBP_Developmental_Growth	Human	Uterus	rep_26	3.8e-06
WDR48	GOBP_Fertilization	Human	Uterus	rep_26	8.7e-10
WDR48	GOBP_Gamete_Generation	Human	Uterus	rep_26	3.8e-10
WDR48	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Uterus	rep_26	1.5e-12
WDR48	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
WDR48	GOBP_Interstrand_Cross_Link_Repair	Human	Uterus	rep_26	6.3e-10
WDR48	GOBP_Male_Gamete_Generation	Human	Uterus	rep_26	7.4e-14
WDR48	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.8e-06
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	2.2e-08
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
WDR48	GOBP_Protein_Modification_By_Small_Protein_Removal	Human	Uterus	rep_26	7.2e-09
WDR48	GOBP_Protein_Monoubiquitination	Human	Uterus	rep_26	5.5e-08
WDR48	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
WDR48	GOBP_Regulation_Of_Protein_Deubiquitination	Human	Uterus	rep_26	4.8e-12
WDR48	GOBP_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	2.9e-09
WDR48	GOBP_Regulation_Of_Protein_Monoubiquitination	Human	Uterus	rep_26	6.0e-10
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Uterus	rep_26	2.1e-07
WDR48	GOBP_Seminiferous_Tubule_Development	Human	Uterus	rep_26	9.1e-07
WDR48	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_29	9.2e-06
WDR48	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
WDR48	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
WDR48	GOBP_Detection_Of_Stimulus	Human	Breast	rep_1	1.8e-04
WDR48	GOBP_Epithelial_Cell_Proliferation	Human	Breast	rep_1	3.1e-42
WDR48	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
WDR48	GOBP_Multicellular_Organism_Growth	Human	Breast	rep_1	2.9e-05
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
WDR48	GOBP_Positive_Regulation_Of_Dna_Recombination	Human	Breast	rep_1	9.9e-127
WDR48	GOBP_Positive_Regulation_Of_Double_Strand_Break_Repair	Human	Breast	rep_1	2.3e-110
WDR48	GOBP_Positive_Regulation_Of_Double_Strand_Break_Repair_Via_Homologous_Recombination	Human	Breast	rep_1	2.1e-163
WDR48	GOBP_Positive_Regulation_Of_Proteolysis	Human	Breast	rep_1	1.7e-07
WDR48	GOBP_Recombinational_Repair	Human	Breast	rep_1	2.9e-09
WDR48	GOBP_Regulation_Of_Dna_Recombination	Human	Breast	rep_1	9.2e-96
WDR48	GOBP_Regulation_Of_Double_Strand_Break_Repair	Human	Breast	rep_1	1.1e-72
WDR48	GOBP_Regulation_Of_Double_Strand_Break_Repair_Via_Homologous_Recombination	Human	Breast	rep_1	6.5e-101
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Breast	rep_1	6.4e-05
WDR48	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
WDR48	GOBP_Skeletal_System_Morphogenesis	Human	Breast	rep_1	6.7e-20
WDR48	GOBP_Skin_Development	Human	Breast	rep_1	2.0e-70
WDR48	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
WDR48	GOBP_Development_Of_Primary_Sexual_Characteristics	Human	Breast	rep_5	3.0e-05
WDR48	GOBP_Developmental_Growth	Human	Breast	rep_5	1.6e-08
WDR48	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Breast	rep_5	1.5e-12
WDR48	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
WDR48	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
WDR48	GOBP_Growth	Human	Breast	rep_5	5.4e-12
WDR48	GOBP_Multicellular_Organism_Reproduction	Human	Breast	rep_5	8.1e-07
WDR48	GOBP_Positive_Regulation_Of_Dna_Repair	Human	Breast	rep_5	1.4e-04
WDR48	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Human	Breast	rep_5	2.6e-13
WDR48	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
WDR48	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
WDR48	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
WDR48	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
WDR48	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
WDR48	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
WDR48	GOBP_Reproductive_System_Development	Human	Breast	rep_5	3.6e-15
WDR48	GOBP_Single_Fertilization	Human	Breast	rep_5	1.0e-04
WDR48	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
WDR48	GOBP_Dna_Metabolic_Process	Human	Breast	rep_6	1.4e-10
WDR48	GOBP_Dna_Recombination	Human	Breast	rep_6	1.4e-06
WDR48	GOBP_Dna_Repair	Human	Breast	rep_6	1.0e-09
WDR48	GOBP_Double_Strand_Break_Repair	Human	Breast	rep_6	2.0e-09
WDR48	GOBP_Fertilization	Human	Breast	rep_6	1.9e-11
WDR48	GOBP_Gamete_Generation	Human	Breast	rep_6	7.3e-08
WDR48	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Breast	rep_6	5.1e-04
WDR48	GOBP_Interstrand_Cross_Link_Repair	Human	Breast	rep_6	7.5e-09
WDR48	GOBP_Male_Gamete_Generation	Human	Breast	rep_6	4.3e-06
WDR48	GOBP_Male_Sex_Differentiation	Human	Breast	rep_6	2.0e-08
WDR48	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	2.4e-08
WDR48	GOBP_Positive_Regulation_Of_Protein_Deubiquitination	Human	Breast	rep_6	2.0e-08
WDR48	GOBP_Positive_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	1.5e-06
WDR48	GOBP_Positive_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	3.8e-06
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
WDR48	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
WDR48	GOBP_Protein_Modification_By_Small_Protein_Removal	Human	Breast	rep_6	1.4e-06
WDR48	GOBP_Protein_Monoubiquitination	Human	Breast	rep_6	2.7e-05
WDR48	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	9.5e-08
WDR48	GOBP_Regulation_Of_Dna_Repair	Human	Breast	rep_6	1.1e-08
WDR48	GOBP_Regulation_Of_Protein_Deubiquitination	Human	Breast	rep_6	2.2e-04
WDR48	GOBP_Regulation_Of_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	1.0e-10
WDR48	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	7.4e-06
WDR48	GOBP_Sex_Differentiation	Human	Breast	rep_6	4.2e-05
WDR48	GOBP_Dna_Repair	Human	Skin	P5_rep1	1.7e-08
WDR48	GOBP_Regulation_Of_Protein_Monoubiquitination	Human	Skin	P5_rep1	4.7e-11
WDR48	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
WDR48	GOBP_Seminiferous_Tubule_Development	Human	Skin	P10_rep1	9.6e-08
WDR48	GOBP_Interstrand_Cross_Link_Repair	Human	Skin	P10_rep2	9.6e-22
WDR48	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
WDR48	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
WDR48	GOBP_Positive_Regulation_Of_Protein_Deubiquitination	Human	Lung	rep_1	9.5e-08
WDR48	GOBP_Regulation_Of_Proteolysis	Human	Lung	rep_1	3.2e-08

Top

WDR48 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

WDR48 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for WDR48 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for WDR48

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for WDR48

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
WDR48	C0037772	Spastic Paraplegia	1	GENOMICS_ENGLAND