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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ARHGAP21 (spascer ID:57584)

Gene summary for ARHGAP21

Gene summary

Gene information
	Species	Human
	Gene symbol	ARHGAP21
	Gene ID	57584
	Gene name	Rho GTPase activating protein 21
	Synonyms	ARHGAP10
	Cytomap	10p12.1\|10p12.3
	Type of gene	protein-coding
	Description	rho GTPase-activating protein 21Rho-GTPase activating protein 10rho GTPase-activating protein 10rho-type GTPase-activating protein 21
	Modification date	20220513
	UniProtAcc	Q5T5U3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ARHGAP21	GO:0051645	Golgi localization	21873635	Process

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Spatial pattern events for ARHGAP21

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ARHGAP21	Human	Brain	rep_9	33558695	3.01e-15
ARHGAP21	Human	Brain	rep_10	33558695	3.23e-15
ARHGAP21	Human	Brain	rep_11	33558695	6.00e-15
ARHGAP21	Human	Brain	rep_12	33558695	3.65e-15
ARHGAP21	Human	Intestine	rep_colon1	34417225	5.35e-12
ARHGAP21	Human	Intestine	rep_colon2	34417225	1.55e-06
ARHGAP21	Human	Intestine	rep_colon4	34417225	1.14e-15
ARHGAP21	Human	Liver	rep_liver1	34417225	1.08e-15
ARHGAP21	Human	Intestine	A4	33406409	5.42e-09
ARHGAP21	Human	Uterus	rep_4	34857954	1.82e-15
ARHGAP21	Human	Breast	1160920F	34493872	1.48e-15
ARHGAP21	Human	Breast	CID44971	34493872	2.18e-14
ARHGAP21	Human	Skin	P2_rep3	32946785	2.54e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Intestine_A4_H&E
Uterus_rep_4_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E
Skin_P2_rep3_H&E

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Spatial pattern pathway has ARHGAP21 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ARHGAP21	GOBP_Maintenance_Of_Location	Human	Brain	rep_1	2.8e-23
ARHGAP21	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
ARHGAP21	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
ARHGAP21	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	1.2e-64
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
ARHGAP21	GOBP_Maintenance_Of_Location	Human	Liver	rep_1	1.0e-70
ARHGAP21	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
ARHGAP21	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
ARHGAP21	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
ARHGAP21	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
ARHGAP21	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
ARHGAP21	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	2.4e-25
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
ARHGAP21	GOBP_Endomembrane_System_Organization	Human	Intestine	A3	1.6e-16
ARHGAP21	GOBP_Establishment_Of_Organelle_Localization	Human	Intestine	A3	9.7e-13
ARHGAP21	GOBP_Golgi_Organization	Human	Intestine	A3	2.9e-07
ARHGAP21	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
ARHGAP21	GOBP_Maintenance_Of_Location	Human	Intestine	A3	7.1e-07
ARHGAP21	GOBP_Maintenance_Of_Location_In_Cell	Human	Intestine	A3	6.1e-08
ARHGAP21	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
ARHGAP21	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
ARHGAP21	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
ARHGAP21	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.8e-12
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
ARHGAP21	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
ARHGAP21	GOBP_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.0e-12
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
ARHGAP21	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	7.5e-12
ARHGAP21	GOBP_Establishment_Of_Golgi_Localization	Human	Intestine	A8	2.8e-13
ARHGAP21	GOBP_Golgi_Localization	Human	Intestine	A8	8.7e-29
ARHGAP21	GOBP_Maintenance_Of_Organelle_Location	Human	Intestine	A8	1.0e-08
ARHGAP21	GOBP_Microtubule_Based_Movement	Human	Intestine	A8	2.9e-10
ARHGAP21	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Intestine	A8	3.1e-07
ARHGAP21	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Intestine	A8	7.1e-10
ARHGAP21	GOBP_Golgi_Organization	Human	Pancreas	PDAC-B-st1	7.2e-05
ARHGAP21	GOBP_Microtubule_Based_Transport	Human	Pancreas	PDAC-B-st1	2.2e-05
ARHGAP21	GOBP_Regulation_Of_Gtpase_Activity	Human	Pancreas	PDAC-B-st1	9.7e-05
ARHGAP21	GOBP_Transport_Along_Microtubule	Human	Pancreas	PDAC-B-st1	2.0e-05
ARHGAP21	GOBP_Organelle_Transport_Along_Microtubule	Human	Uterus	rep_26	4.4e-06
ARHGAP21	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Uterus	rep_26	9.8e-09
ARHGAP21	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Uterus	rep_26	4.7e-08
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
ARHGAP21	GOBP_Endomembrane_System_Organization	Human	Breast	rep_1	2.2e-04
ARHGAP21	GOBP_Establishment_Of_Golgi_Localization	Human	Breast	rep_1	4.4e-86
ARHGAP21	GOBP_Establishment_Of_Organelle_Localization	Human	Breast	rep_1	6.5e-08
ARHGAP21	GOBP_Golgi_Localization	Human	Breast	rep_1	6.9e-97
ARHGAP21	GOBP_Golgi_Organization	Human	Breast	rep_1	6.6e-40
ARHGAP21	GOBP_Maintenance_Of_Location	Human	Breast	rep_1	3.8e-39
ARHGAP21	GOBP_Maintenance_Of_Location_In_Cell	Human	Breast	rep_1	1.4e-24
ARHGAP21	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
ARHGAP21	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	1.4e-13
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
ARHGAP21	GOBP_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	9.6e-08
ARHGAP21	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Breast	rep_1	3.4e-04
ARHGAP21	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
ARHGAP21	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
ARHGAP21	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	8.7e-11
ARHGAP21	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Breast	rep_5	2.0e-07
ARHGAP21	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
ARHGAP21	GOBP_Microtubule_Based_Movement	Human	Breast	rep_6	8.5e-09
ARHGAP21	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
ARHGAP21	GOBP_Microtubule_Based_Transport	Human	Breast	rep_6	2.9e-09
ARHGAP21	GOBP_Organelle_Transport_Along_Microtubule	Human	Breast	rep_6	1.9e-05
ARHGAP21	GOBP_Transport_Along_Microtubule	Human	Breast	rep_6	1.5e-05
ARHGAP21	GOBP_Maintenance_Of_Location_In_Cell	Human	Skin	P2_rep1	9.7e-09
ARHGAP21	GOBP_Microtubule_Based_Movement	Human	Skin	P5_rep1	2.1e-08
ARHGAP21	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
ARHGAP21	GOBP_Organelle_Transport_Along_Microtubule	Human	Skin	P5_rep1	7.4e-08
ARHGAP21	GOBP_Microtubule_Based_Transport	Human	Skin	P5_rep3	8.3e-08
ARHGAP21	GOBP_Transport_Along_Microtubule	Human	Skin	P5_rep3	7.3e-13
ARHGAP21	GOBP_Maintenance_Of_Organelle_Location	Human	Skin	P10_rep1	3.7e-12
ARHGAP21	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
ARHGAP21	GOBP_Maintenance_Of_Location	Human	Lung	rep_2	1.1e-08
ARHGAP21	GOBP_Maintenance_Of_Location_In_Cell	Human	Lung	rep_2	2.8e-08
ARHGAP21	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07

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ARHGAP21 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ARHGAP21 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ARHGAP21 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ARHGAP21

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ARHGAP21

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source