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Spatial pattern gene: TMEM181 (spascer ID:57583) |
Gene summary for TMEM181 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | TMEM181 | Gene ID | 57583 |
| Gene name | transmembrane protein 181 |
| Synonyms | GPR178|KIAA1423 |
| Cytomap | 6q25.3 |
| Type of gene | protein-coding |
| Description | transmembrane protein 181G protein-coupled receptor 178 |
| Modification date | 20220513 |
| UniProtAcc | Q9P2C4 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| TMEM181 | GO:0015643 | toxic substance binding | 21873635 | Function |
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Spatial pattern events for TMEM181 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| TMEM181 | Human | Intestine | rep_colon1 | 34417225 | 4.28e-11 |
| TMEM181 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| TMEM181 | Human | Intestine | rep_colon4 | 34417225 | 2.31e-13 |
| TMEM181 | Human | Liver | rep_liver1 | 34417225 | 1.76e-14 |
| TMEM181 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| TMEM181 | Human | Intestine | A2 | 33406409 | 4.58e-10 |
| TMEM181 | Human | Uterus | rep_4 | 34857954 | 8.08e-14 |
| TMEM181 | Human | Breast | 1142243F | 34493872 | 1.27e-10 |
| TMEM181 | Human | Breast | CID4290 | 34493872 | 1.02e-11 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_4_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_CID4290_H&E  |  |
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Spatial pattern pathway has TMEM181 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
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TMEM181 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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TMEM181 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for TMEM181 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for TMEM181 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TMEM181 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
