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Spatial pattern gene: NCEH1 (spascer ID:57552) |
Gene summary for NCEH1 |
Gene summary |
| Gene information | |
| Species | Human | Gene symbol | NCEH1 | Gene ID | 57552 |
| Gene name | neutral cholesterol ester hydrolase 1 |
| Synonyms | AADACL1|NCEH |
| Cytomap | 3q26.31 |
| Type of gene | protein-coding |
| Description | neutral cholesterol ester hydrolase 1acetylalkylglycerol acetylhydrolasealkylacetylglycerol acetylhydrolasearylacetamide deacetylase-like 1 |
| Modification date | 20220513 |
| UniProtAcc | Q6PIU2 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| NCEH1 | GO:0016787 | hydrolase activity | 21873635 | Function |
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Spatial pattern events for NCEH1 |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| NCEH1 | Human | Brain | rep_9 | 33558695 | 1.29e-11 |
| NCEH1 | Human | Brain | rep_10 | 33558695 | 5.75e-15 |
| NCEH1 | Human | Brain | rep_11 | 33558695 | 2.35e-08 |
| NCEH1 | Human | Brain | rep_12 | 33558695 | 8.26e-14 |
| NCEH1 | Human | Intestine | rep_colon1 | 34417225 | 3.41e-08 |
| NCEH1 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| NCEH1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| NCEH1 | Human | Intestine | A2 | 33406409 | 1.82e-09 |
| NCEH1 | Human | Breast | 1160920F | 34493872 | 4.23e-08 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has NCEH1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| NCEH1 | GOBP_Lipid_Metabolic_Process | Human | Brain | rep_1 | 2.8e-23 |
| NCEH1 | GOBP_Lipid_Metabolic_Process | Human | Liver | rep_1 | 1.0e-70 |
| NCEH1 | GOBP_Cellular_Lipid_Metabolic_Process | Human | Intestine | A8 | 3.8e-13 |
| NCEH1 | GOBP_Ether_Metabolic_Process | Human | Intestine | A8 | 5.3e-25 |
| NCEH1 | GOBP_Glycerol_Ether_Metabolic_Process | Human | Intestine | A8 | 7.9e-15 |
| NCEH1 | GOBP_Lipid_Catabolic_Process | Human | Intestine | A8 | 3.2e-08 |
| NCEH1 | GOBP_Lipid_Metabolic_Process | Human | Intestine | A8 | 1.1e-11 |
| NCEH1 | GOBP_Small_Molecule_Metabolic_Process | Human | Intestine | A8 | 2.1e-15 |
| NCEH1 | GOBP_Low_Density_Lipoprotein_Particle_Clearance | Human | Uterus | rep_26 | 2.5e-13 |
| NCEH1 | GOBP_Low_Density_Lipoprotein_Particle_Clearance | Human | Breast | rep_1 | 1.3e-51 |
| NCEH1 | GOBP_Plasma_Lipoprotein_Particle_Clearance | Human | Breast | rep_1 | 2.3e-47 |
| NCEH1 | GOBP_Regulation_Of_Plasma_Lipoprotein_Particle_Levels | Human | Breast | rep_1 | 1.5e-50 |
| NCEH1 | GOBP_Cellular_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.6e-07 |
| NCEH1 | GOBP_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.9e-06 |
| NCEH1 | GOBP_Ether_Metabolic_Process | Human | Breast | rep_6 | 1.3e-04 |
| NCEH1 | GOBP_Glycerol_Ether_Metabolic_Process | Human | Breast | rep_6 | 6.1e-04 |
| NCEH1 | GOBP_Lipid_Catabolic_Process | Human | Breast | rep_6 | 2.9e-05 |
| NCEH1 | GOBP_Small_Molecule_Metabolic_Process | Human | Breast | rep_6 | 5.5e-09 |
| NCEH1 | GOBP_Low_Density_Lipoprotein_Particle_Clearance | Human | Skin | P5_rep1 | 6.0e-09 |
| NCEH1 | GOBP_Ether_Metabolic_Process | Human | Skin | P10_rep2 | 1.7e-16 |
| NCEH1 | GOBP_Glycerol_Ether_Metabolic_Process | Human | Skin | P10_rep2 | 2.4e-09 |
| NCEH1 | GOBP_Lipid_Catabolic_Process | Human | Lung | rep_2 | 1.4e-09 |
| NCEH1 | GOBP_Plasma_Lipoprotein_Particle_Clearance | Human | Lung | rep_2 | 5.0e-07 |
| NCEH1 | GOBP_Regulation_Of_Plasma_Lipoprotein_Particle_Levels | Human | Lung | rep_2 | 4.5e-08 |
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NCEH1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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NCEH1 function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for NCEH1 envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for NCEH1 |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NCEH1 |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |