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Spatial pattern gene: CGN (spascer ID:57530) |
Gene summary for CGN |
Gene summary |
| Gene information | |
| Species | Human | Gene symbol | CGN | Gene ID | 57530 |
| Gene name | cingulin |
| Synonyms | - |
| Cytomap | 1q21.3 |
| Type of gene | protein-coding |
| Description | cingulin |
| Modification date | 20220513 |
| UniProtAcc | Q9P2M7 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for CGN |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| CGN | Human | Intestine | rep_colon1 | 34417225 | 2.81e-10 |
| CGN | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| CGN | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| CGN | Human | Intestine | A1 | 33406409 | 2.09e-15 |
| CGN | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| CGN | Human | Intestine | A4 | 33406409 | 9.63e-15 |
| CGN | Human | Intestine | A6 | 33406409 | 3.31e-13 |
| CGN | Human | Intestine | A8 | 33406409 | 2.82e-14 |
| CGN | Human | Intestine | A9 | 33406409 | 5.42e-14 |
| CGN | Human | Breast | 1160920F | 34493872 | 5.57e-13 |
| CGN | Human | Breast | CID4535 | 34493872 | 3.26e-11 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has CGN envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| CGN | GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway | Human | Brain | rep_1 | 2.3e-68 |
| CGN | GOBP_Response_To_Endogenous_Stimulus | Human | Brain | rep_10 | 2.8e-23 |
| CGN | GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway | Human | Bladder | rep_2 | 1.3e-05 |
| CGN | GOBP_Response_To_Growth_Factor | Human | Bladder | rep_2 | 1.2e-08 |
| CGN | GOBP_Response_To_Transforming_Growth_Factor_Beta | Human | Bladder | rep_2 | 1.5e-11 |
| CGN | GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway | Human | Bladder | rep_2 | 2.2e-29 |
| CGN | GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway | Human | Bladder | rep_2 | 2.5e-23 |
| CGN | GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway | Human | Liver | rep_1 | 8.8e-90 |
| CGN | GOBP_Response_To_Endogenous_Stimulus | Human | Liver | rep_1 | 3.0e-55 |
| CGN | GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway | Human | Intestine | rep_colon2 | 5.0e-29 |
| CGN | GOBP_Response_To_Endogenous_Stimulus | Human | Intestine | rep_liver2 | 3.7e-39 |
| CGN | GOBP_Response_To_Endogenous_Stimulus | Human | Intestine | A3 | 5.2e-09 |
| CGN | GOBP_Response_To_Transforming_Growth_Factor_Beta | Human | Intestine | A8 | 1.1e-10 |
| CGN | GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway | Human | Intestine | A8 | 5.8e-13 |
| CGN | GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway | Human | Pancreas | PDAC-B-st1 | 1.5e-05 |
| CGN | GOBP_Response_To_Growth_Factor | Human | Breast | rep_1 | 1.2e-13 |
| CGN | GOBP_Response_To_Transforming_Growth_Factor_Beta | Human | Breast | rep_1 | 2.4e-65 |
| CGN | GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway | Human | Breast | rep_1 | 4.6e-27 |
| CGN | GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway | Human | Breast | rep_5 | 4.6e-14 |
| CGN | GOBP_Response_To_Endogenous_Stimulus | Human | Breast | rep_5 | 3.6e-09 |
| CGN | GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway | Human | Breast | rep_5 | 4.5e-06 |
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CGN function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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CGN function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for CGN envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for CGN |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CGN |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |