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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: CGN (spascer ID:57530)

Gene summary for CGN

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

CGN

Gene ID

57530

Gene namecingulin
Synonyms-
Cytomap1q21.3
Type of geneprotein-coding
Descriptioncingulin
Modification date20220513
UniProtAcc

Q9P2M7


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory

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Spatial pattern events for CGN

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
CGNHumanIntestinerep_colon1 344172252.81e-10
CGNHumanIntestinerep_colon4 344172251.14e-15
CGNHumanLiverrep_liver2 344172256.98e-16
CGNHumanIntestineA1 334064092.09e-15
CGNHumanIntestineA2 334064092.47e-15
CGNHumanIntestineA4 334064099.63e-15
CGNHumanIntestineA6 334064093.31e-13
CGNHumanIntestineA8 334064092.82e-14
CGNHumanIntestineA9 334064095.42e-14
CGNHumanBreast1160920F 344938725.57e-13
CGNHumanBreastCID4535 344938723.26e-11

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
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boxplot
Liver_rep_liver2_H&E
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boxplot
Intestine_A1_H&E
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boxplot
Intestine_A2_H&E
boxplot

boxplot
Intestine_A4_H&E
boxplot

boxplot
Intestine_A6_H&E
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boxplot
Intestine_A8_H&E
boxplot

boxplot
Intestine_A9_H&E
boxplot

boxplot
Breast_1160920F_H&E
boxplot

boxplot
Breast_CID4535_H&E
boxplot

boxplot


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Spatial pattern pathway has CGN envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
CGNGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayHumanBrainrep_1 2.3e-68
CGNGOBP_Response_To_Endogenous_StimulusHumanBrainrep_10 2.8e-23
CGNGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayHumanBladderrep_2 1.3e-05
CGNGOBP_Response_To_Growth_FactorHumanBladderrep_2 1.2e-08
CGNGOBP_Response_To_Transforming_Growth_Factor_BetaHumanBladderrep_2 1.5e-11
CGNGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayHumanBladderrep_2 2.2e-29
CGNGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayHumanBladderrep_2 2.5e-23
CGNGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayHumanLiverrep_1 8.8e-90
CGNGOBP_Response_To_Endogenous_StimulusHumanLiverrep_1 3.0e-55
CGNGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayHumanIntestinerep_colon2 5.0e-29
CGNGOBP_Response_To_Endogenous_StimulusHumanIntestinerep_liver2 3.7e-39
CGNGOBP_Response_To_Endogenous_StimulusHumanIntestineA3 5.2e-09
CGNGOBP_Response_To_Transforming_Growth_Factor_BetaHumanIntestineA8 1.1e-10
CGNGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayHumanIntestineA8 5.8e-13
CGNGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayHumanPancreasPDAC-B-st1 1.5e-05
CGNGOBP_Response_To_Growth_FactorHumanBreastrep_1 1.2e-13
CGNGOBP_Response_To_Transforming_Growth_Factor_BetaHumanBreastrep_1 2.4e-65
CGNGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayHumanBreastrep_1 4.6e-27
CGNGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayHumanBreastrep_5 4.6e-14
CGNGOBP_Response_To_Endogenous_StimulusHumanBreastrep_5 3.6e-09
CGNGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayHumanBreastrep_5 4.5e-06

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CGN function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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CGN function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for CGN envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for CGN

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CGN

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource