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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: XPO5 (spascer ID:57510)

Gene summary for XPO5

Gene summary

Gene information
	Species	Human
	Gene symbol	XPO5
	Gene ID	57510
	Gene name	exportin 5
	Synonyms	exp5
	Cytomap	6p21.1
	Type of gene	protein-coding
	Description	exportin-5ran-binding protein 21
	Modification date	20220513
	UniProtAcc	Q9HAV4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
XPO5	GO:0003723	RNA binding	21873635	Function
XPO5	GO:0005049	nuclear export signal receptor activity	21873635	Function
XPO5	GO:0005634	nucleus	21873635	Component
XPO5	GO:0005737	cytoplasm	21873635	Component
XPO5	GO:0006405	RNA export from nucleus	21873635	Process
XPO5	GO:0042565	RNA nuclear export complex	21873635	Component

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Spatial pattern events for XPO5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
XPO5	Human	Liver	rep_liver1	34417225	1.08e-15
XPO5	Human	Liver	rep_liver2	34417225	6.98e-16
XPO5	Human	Uterus	rep_3	34857954	1.66e-15
XPO5	Human	Breast	CID44971	34493872	6.33e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_3_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has XPO5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
XPO5	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
XPO5	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
XPO5	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
XPO5	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
XPO5	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
XPO5	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
XPO5	GOBP_Ncrna_Metabolic_Process	Human	Intestine	A3	8.6e-07
XPO5	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
XPO5	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
XPO5	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
XPO5	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
XPO5	GOBP_Positive_Regulation_Of_Posttranscriptional_Gene_Silencing	Human	Intestine	A3	3.7e-12
XPO5	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Human	Intestine	A3	4.2e-08
XPO5	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
XPO5	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
XPO5	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Intestine	A8	4.6e-12
XPO5	GOBP_Rna_Interference	Human	Intestine	A8	1.1e-08
XPO5	GOBP_Positive_Regulation_Of_Posttranscriptional_Gene_Silencing	Human	Pancreas	PDAC-B-st1	3.3e-05
XPO5	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Pancreas	PDAC-B-st1	1.7e-05
XPO5	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
XPO5	GOBP_Positive_Regulation_Of_Posttranscriptional_Gene_Silencing	Human	Uterus	rep_1	5.3e-07
XPO5	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Uterus	rep_1	4.7e-07
XPO5	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
XPO5	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
XPO5	GOBP_Rna_Interference	Human	Uterus	rep_25	3.1e-15
XPO5	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
XPO5	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
XPO5	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
XPO5	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
XPO5	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
XPO5	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
XPO5	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
XPO5	GOBP_Mirna_Metabolic_Process	Human	Breast	rep_1	1.1e-06
XPO5	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
XPO5	GOBP_Positive_Regulation_Of_Posttranscriptional_Gene_Silencing	Human	Breast	rep_5	2.0e-04
XPO5	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Breast	rep_5	4.0e-10
XPO5	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
XPO5	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
XPO5	GOBP_Ncrna_Metabolic_Process	Human	Breast	rep_6	1.9e-04
XPO5	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
XPO5	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
XPO5	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
XPO5	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
XPO5	GOBP_Mirna_Metabolic_Process	Human	Skin	P5_rep1	1.0e-09
XPO5	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
XPO5	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
XPO5	GOBP_Rna_Interference	Human	Skin	P10_rep2	1.1e-18
XPO5	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10

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XPO5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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XPO5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for XPO5 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for XPO5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for XPO5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
XPO5	C0023176	Lead Poisoning	1	CTD_human
XPO5	C0027708	Nephroblastoma	1	CTD_human
XPO5	C0027726	Nephrotic Syndrome	1	GENOMICS_ENGLAND
XPO5	C0920269	Microsatellite Instability	1	CTD_human
XPO5	C1721098	Replication Error Phenotype	1	CTD_human
XPO5	C1868672	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	1	CTD_human
XPO5	C2930471	Bilateral Wilms Tumor	1	CTD_human