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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: MTUS1 (spascer ID:57509)

Gene summary for MTUS1

Gene summary

Gene information
	Species	Human
	Gene symbol	MTUS1
	Gene ID	57509
	Gene name	microtubule associated scaffold protein 1
	Synonyms	ATBP\|ATIP\|ATIP3\|ICIS\|MP44\|MTSG1
	Cytomap	8p22
	Type of gene	protein-coding
	Description	microtubule-associated tumor suppressor 1AT2 receptor-binding proteinAT2 receptor-interacting proteinAT2R binding proteinangiotensin-II type 2 receptor-interacting proteinerythroid differentiation-relatedmicrotubule associated tumor suppressor 1mit
	Modification date	20220513
	UniProtAcc	Q9ULD2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
MTUS1	GO:0005634	nucleus	21873635	Component
MTUS1	GO:0005737	cytoplasm	21873635	Component
MTUS1	GO:0008017	microtubule binding	21873635	Function
MTUS1	GO:0010758	regulation of macrophage chemotaxis	21873635	Process

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Spatial pattern events for MTUS1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
MTUS1	Human	Brain	rep_9	33558695	3.01e-15
MTUS1	Human	Brain	rep_10	33558695	3.23e-15
MTUS1	Human	Brain	rep_11	33558695	3.36e-15
MTUS1	Human	Brain	rep_12	33558695	3.65e-15
MTUS1	Human	Intestine	rep_colon1	34417225	1.95e-15
MTUS1	Human	Intestine	rep_colon2	34417225	1.48e-15
MTUS1	Human	Intestine	rep_colon4	34417225	1.14e-15
MTUS1	Human	Liver	rep_liver1	34417225	1.08e-15
MTUS1	Human	Liver	rep_liver2	34417225	6.98e-16
MTUS1	Human	Breast	CID4290	34493872	2.74e-07
MTUS1	Human	Breast	CID44971	34493872	1.76e-15
MTUS1	Human	Heart	w6_s4	31835037	5.99e-03
MTUS1	Human	Heart	w6_s5	31835037	6.72e-04
MTUS1	Human	Heart	w6_s6	31835037	1.12e-04

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Breast_CID4290_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has MTUS1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
MTUS1	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
MTUS1	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
MTUS1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Brain	rep_1	3.1e-68
MTUS1	GOBP_Regulation_Of_Chemotaxis	Human	Brain	rep_1	2.3e-68
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
MTUS1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Brain	rep_1	4.6e-05
MTUS1	GOBP_Taxis	Human	Brain	rep_1	2.3e-68
MTUS1	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
MTUS1	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
MTUS1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Liver	rep_1	1.9e-71
MTUS1	GOBP_Regulation_Of_Chemotaxis	Human	Liver	rep_1	8.8e-90
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
MTUS1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Liver	rep_1	5.3e-67
MTUS1	GOBP_Taxis	Human	Liver	rep_1	8.8e-90
MTUS1	GOBP_Regulation_Of_Chemotaxis	Human	Intestine	rep_colon2	5.0e-29
MTUS1	GOBP_Taxis	Human	Intestine	rep_colon2	5.0e-29
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
MTUS1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	rep_colon4	2.2e-52
MTUS1	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
MTUS1	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
MTUS1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	rep_liver2	1.0e-64
MTUS1	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
MTUS1	GOBP_Leukocyte_Migration	Human	Intestine	A3	1.5e-08
MTUS1	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
MTUS1	GOBP_Myeloid_Leukocyte_Migration	Human	Intestine	A3	1.3e-07
MTUS1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	A3	1.1e-09
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
MTUS1	GOBP_Regulation_Of_Leukocyte_Migration	Human	Intestine	A3	5.1e-09
MTUS1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Intestine	A3	1.0e-09
MTUS1	GOBP_Taxis	Human	Intestine	A3	5.0e-08
MTUS1	GOBP_Leukocyte_Chemotaxis	Human	Intestine	A8	3.7e-14
MTUS1	GOBP_Macrophage_Chemotaxis	Human	Intestine	A8	9.7e-18
MTUS1	GOBP_Macrophage_Migration	Human	Intestine	A8	8.3e-14
MTUS1	GOBP_Regulation_Of_Leukocyte_Chemotaxis	Human	Intestine	A8	5.2e-09
MTUS1	GOBP_Regulation_Of_Macrophage_Chemotaxis	Human	Intestine	A8	6.1e-07
MTUS1	GOBP_Macrophage_Migration	Human	Pancreas	PDAC-B-st1	3.4e-05
MTUS1	GOBP_Regulation_Of_Leukocyte_Chemotaxis	Human	Pancreas	PDAC-A-st3	5.5e-05
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
MTUS1	GOBP_Macrophage_Chemotaxis	Human	Uterus	rep_1	1.3e-07
MTUS1	GOBP_Regulation_Of_Macrophage_Migration	Human	Uterus	rep_1	1.4e-07
MTUS1	GOBP_Macrophage_Migration	Human	Uterus	rep_26	4.9e-06
MTUS1	GOBP_Regulation_Of_Macrophage_Chemotaxis	Human	Uterus	rep_26	1.7e-06
MTUS1	GOBP_Leukocyte_Migration	Human	Uterus	rep_29	1.5e-07
MTUS1	GOBP_Regulation_Of_Leukocyte_Migration	Human	Uterus	rep_29	6.5e-06
MTUS1	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
MTUS1	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
MTUS1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Breast	rep_1	5.5e-21
MTUS1	GOBP_Regulation_Of_Chemotaxis	Human	Breast	rep_1	2.8e-07
MTUS1	GOBP_Regulation_Of_Response_To_External_Stimulus	Human	Breast	rep_1	2.9e-17
MTUS1	GOBP_Cell_Chemotaxis	Human	Breast	rep_5	5.7e-10
MTUS1	GOBP_Leukocyte_Chemotaxis	Human	Breast	rep_5	5.0e-12
MTUS1	GOBP_Leukocyte_Migration	Human	Breast	rep_5	6.0e-14
MTUS1	GOBP_Myeloid_Leukocyte_Migration	Human	Breast	rep_5	2.3e-11
MTUS1	GOBP_Taxis	Human	Breast	rep_5	1.2e-12
MTUS1	GOBP_Taxis	Human	Skin	P2_rep2	1.2e-08
MTUS1	GOBP_Macrophage_Migration	Human	Skin	P10_rep3	1.2e-09
MTUS1	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
MTUS1	GOBP_Taxis	Human	Lung	rep_2	4.0e-07

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MTUS1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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MTUS1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for MTUS1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for MTUS1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for MTUS1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
MTUS1	C2239176	Liver carcinoma	1	UNIPROT