Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: KIDINS220 (spascer ID:57498)

Gene summary for KIDINS220

Gene summary

Gene information
	Species	Human
	Gene symbol	KIDINS220
	Gene ID	57498
	Gene name	kinase D interacting substrate 220
	Synonyms	ARMS\|SINO\|VENARG
	Cytomap	2p25.1
	Type of gene	protein-coding
	Description	kinase D-interacting substrate of 220 kDaankyrin repeat-rich membrane-spanning proteinkinase D-interacting substrate 220kDa
	Modification date	20220513
	UniProtAcc	Q9ULH0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
KIDINS220	GO:0019887	protein kinase regulator activity	21873635	Function
KIDINS220	GO:0030165	PDZ domain binding	21873635	Function
KIDINS220	GO:0038180	nerve growth factor signaling pathway	21873635	Process

Top

Spatial pattern events for KIDINS220

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
KIDINS220	Human	Brain	rep_8	33558695	6.09e-06
KIDINS220	Human	Intestine	rep_colon2	34417225	1.90e-12
KIDINS220	Human	Liver	rep_liver2	34417225	6.98e-16
KIDINS220	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_8_H&E
Intestine_rep_colon2_H&E
Liver_rep_liver2_H&E
Breast_CID44971_H&E

Top

Spatial pattern pathway has KIDINS220 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
KIDINS220	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
KIDINS220	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
KIDINS220	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	2.8e-23
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	2.8e-23
KIDINS220	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	7.4e-34
KIDINS220	GOBP_Cell_Morphogenesis	Human	Brain	rep_4	1.0e-14
KIDINS220	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
KIDINS220	GOBP_Response_To_Growth_Factor	Human	Bladder	rep_2	1.2e-08
KIDINS220	GOBP_Cell_Morphogenesis	Human	Liver	rep_1	2.1e-52
KIDINS220	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
KIDINS220	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
KIDINS220	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
KIDINS220	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
KIDINS220	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
KIDINS220	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
KIDINS220	GOBP_Cell_Morphogenesis	Human	Intestine	rep_colon2	1.5e-57
KIDINS220	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
KIDINS220	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
KIDINS220	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
KIDINS220	GOBP_Cell_Morphogenesis	Human	Intestine	A3	9.7e-08
KIDINS220	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Intestine	A3	3.7e-07
KIDINS220	GOBP_Cell_Part_Morphogenesis	Human	Intestine	A3	8.9e-08
KIDINS220	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
KIDINS220	GOBP_Dendrite_Morphogenesis	Human	Intestine	A3	1.6e-08
KIDINS220	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
KIDINS220	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
KIDINS220	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
KIDINS220	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
KIDINS220	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
KIDINS220	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	1.2e-09
KIDINS220	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
KIDINS220	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
KIDINS220	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	7.8e-15
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	2.0e-08
KIDINS220	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
KIDINS220	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
KIDINS220	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Intestine	A3	2.0e-09
KIDINS220	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
KIDINS220	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
KIDINS220	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	8.8e-11
KIDINS220	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
KIDINS220	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
KIDINS220	GOBP_Neurotrophin_Signaling_Pathway	Human	Intestine	A8	1.1e-11
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Intestine	A8	1.1e-12
KIDINS220	GOBP_Response_To_Nerve_Growth_Factor	Human	Intestine	A8	8.7e-16
KIDINS220	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.9e-05
KIDINS220	GOBP_Nerve_Growth_Factor_Signaling_Pathway	Human	Uterus	rep_25	1.4e-07
KIDINS220	GOBP_Neurotrophin_Signaling_Pathway	Human	Uterus	rep_25	1.2e-09
KIDINS220	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Uterus	rep_26	2.8e-13
KIDINS220	GOBP_Dendrite_Development	Human	Uterus	rep_26	3.9e-07
KIDINS220	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
KIDINS220	GOBP_Cell_Morphogenesis	Human	Breast	rep_1	5.7e-26
KIDINS220	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Breast	rep_1	1.6e-61
KIDINS220	GOBP_Cell_Morphogenesis_Involved_In_Neuron_Differentiation	Human	Breast	rep_1	1.4e-48
KIDINS220	GOBP_Cell_Part_Morphogenesis	Human	Breast	rep_1	6.2e-28
KIDINS220	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
KIDINS220	GOBP_Cellular_Component_Morphogenesis	Human	Breast	rep_1	2.7e-58
KIDINS220	GOBP_Dendrite_Morphogenesis	Human	Breast	rep_1	6.4e-04
KIDINS220	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Human	Breast	rep_1	7.7e-07
KIDINS220	GOBP_In_Utero_Embryonic_Development	Human	Breast	rep_1	1.5e-18
KIDINS220	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
KIDINS220	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
KIDINS220	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
KIDINS220	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	1.6e-25
KIDINS220	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
KIDINS220	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
KIDINS220	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Breast	rep_1	7.3e-24
KIDINS220	GOBP_Response_To_Growth_Factor	Human	Breast	rep_1	1.2e-13
KIDINS220	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
KIDINS220	GOBP_Nerve_Growth_Factor_Signaling_Pathway	Human	Breast	rep_5	4.2e-08
KIDINS220	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
KIDINS220	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
KIDINS220	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	5.9e-12
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	1.0e-15
KIDINS220	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
KIDINS220	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_5	1.4e-06
KIDINS220	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
KIDINS220	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	5.8e-14
KIDINS220	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
KIDINS220	GOBP_Response_To_Nerve_Growth_Factor	Human	Breast	rep_5	9.1e-19
KIDINS220	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.8e-04
KIDINS220	GOBP_Dendrite_Development	Human	Breast	rep_6	6.3e-05
KIDINS220	GOBP_Neurotrophin_Signaling_Pathway	Human	Breast	rep_6	1.7e-04
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.5e-05
KIDINS220	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
KIDINS220	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
KIDINS220	GOBP_Cell_Morphogenesis_Involved_In_Neuron_Differentiation	Human	Skin	P2_rep1	9.6e-08
KIDINS220	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Human	Skin	P5_rep1	1.1e-09
KIDINS220	GOBP_Dendrite_Development	Human	Skin	P5_rep1	3.7e-10
KIDINS220	GOBP_Dendrite_Morphogenesis	Human	Skin	P5_rep1	3.2e-11
KIDINS220	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	7.4e-09
KIDINS220	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	3.2e-09
KIDINS220	GOBP_Positive_Regulation_Of_Neuron_Projection_Development	Human	Lung	rep_2	4.3e-10

Top

KIDINS220 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

KIDINS220 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
NGF	KIDINS220	NGF_KIDINS220	Brain	rep_5

Top

Transcription factor for KIDINS220 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for KIDINS220

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for KIDINS220

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
KIDINS220	C4284592	SPASTIC PARAPLEGIA, INTELLECTUAL DISABILITY, NYSTAGMUS, AND OBESITY	2	GENOMICS_ENGLAND;ORPHANET