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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: MRTFB (spascer ID:57496)

Gene summary for MRTFB

Gene summary

Gene information
	Species	Human
	Gene symbol	MRTFB
	Gene ID	57496
	Gene name	myocardin related transcription factor B
	Synonyms	MKL2\|MRTF-B\|NPD001
	Cytomap	16p13.12
	Type of gene	protein-coding
	Description	myocardin-related transcription factor BCTA-276F8.1MKL and myocardin family member 2MKL/myocardin like 2MKL/myocardin-like protein 2MKL1/myocardin like 2megakaryoblastic leukemia 2
	Modification date	20220513
	UniProtAcc	Q9ULH7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
MRTFB	GO:0003713	transcription coactivator activity	21873635	Function
MRTFB	GO:0005634	nucleus	21873635	Component
MRTFB	GO:0045944	positive regulation of transcription by RNA polymerase II	21873635	Process
MRTFB	GO:0051145	smooth muscle cell differentiation	21873635	Process

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Spatial pattern events for MRTFB

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
MRTFB	Human	Liver	rep_liver2	34417225	6.98e-16
MRTFB	Human	Lung	rep_1	35355018	5.18e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver2_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has MRTFB envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
MRTFB	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
MRTFB	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
MRTFB	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
MRTFB	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
MRTFB	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
MRTFB	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
MRTFB	GOBP_Smooth_Muscle_Cell_Differentiation	Human	Intestine	A3	7.5e-10
MRTFB	GOBP_Positive_Regulation_Of_Muscle_Tissue_Development	Human	Intestine	A8	3.1e-15
MRTFB	GOBP_Regulation_Of_Muscle_Organ_Development	Human	Intestine	A8	1.3e-16
MRTFB	GOBP_Positive_Regulation_Of_Muscle_Tissue_Development	Human	Uterus	rep_25	7.3e-14
MRTFB	GOBP_Regulation_Of_Muscle_Organ_Development	Human	Uterus	rep_25	4.6e-06
MRTFB	GOBP_Muscle_Organ_Development	Human	Uterus	rep_26	6.5e-08
MRTFB	GOBP_Muscle_Tissue_Development	Human	Uterus	rep_26	1.2e-10
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
MRTFB	GOBP_Muscle_Cell_Differentiation	Human	Breast	rep_1	2.9e-50
MRTFB	GOBP_Muscle_Organ_Development	Human	Breast	rep_1	1.5e-42
MRTFB	GOBP_Muscle_Structure_Development	Human	Breast	rep_1	6.8e-61
MRTFB	GOBP_Muscle_Tissue_Development	Human	Breast	rep_1	1.0e-09
MRTFB	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
MRTFB	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
MRTFB	GOBP_Smooth_Muscle_Cell_Differentiation	Human	Breast	rep_1	1.7e-14
MRTFB	GOBP_Positive_Regulation_Of_Muscle_Tissue_Development	Human	Breast	rep_5	3.1e-10
MRTFB	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
MRTFB	GOBP_Regulation_Of_Muscle_Organ_Development	Human	Breast	rep_5	1.5e-05
MRTFB	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
MRTFB	GOBP_Smooth_Muscle_Cell_Differentiation	Human	Lung	rep_1	2.6e-09

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MRTFB function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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MRTFB function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for MRTFB envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for MRTFB

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for MRTFB

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source