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Spatial pattern gene: PPM1H (spascer ID:57460) |
Gene summary for PPM1H |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | PPM1H | Gene ID | 57460 |
| Gene name | protein phosphatase, Mg2+/Mn2+ dependent 1H |
| Synonyms | ARHCL1|NERPP-2C|URCC2 |
| Cytomap | 12q14.1-q14.2 |
| Type of gene | protein-coding |
| Description | protein phosphatase 1Hneurite extension-related protein phosphatase related to PP2Cprotein phosphatase 1H (PP2C domain containing)ras homolog gene family, member C like 1 |
| Modification date | 20220513 |
| UniProtAcc | Q9ULR3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| PPM1H | GO:0006470 | protein dephosphorylation | 21873635 | Process |
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Spatial pattern events for PPM1H |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| PPM1H | Human | Intestine | rep_colon1 | 34417225 | 1.80e-07 |
| PPM1H | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| PPM1H | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| PPM1H | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| PPM1H | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
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Spatial pattern pathway has PPM1H envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| PPM1H | GOBP_Dephosphorylation | Human | Intestine | A3 | 3.1e-14 |
| PPM1H | GOBP_Protein_Dephosphorylation | Human | Intestine | A3 | 1.0e-10 |
| PPM1H | GOBP_Dephosphorylation | Human | Breast | rep_6 | 2.8e-05 |
| PPM1H | GOBP_Protein_Dephosphorylation | Human | Breast | rep_6 | 6.7e-05 |
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PPM1H function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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PPM1H function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for PPM1H envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for PPM1H |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PPM1H |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
