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Spatial pattern gene: NDRG3 (spascer ID:57446) |
Gene summary for NDRG3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | NDRG3 | Gene ID | 57446 |
| Gene name | NDRG family member 3 |
| Synonyms | - |
| Cytomap | 20q11.23 |
| Type of gene | protein-coding |
| Description | protein NDRG3N-myc downstream-regulated gene 3 protein |
| Modification date | 20220513 |
| UniProtAcc | Q9UGV2 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| NDRG3 | GO:0005737 | cytoplasm | 21873635 | Component |
| NDRG3 | GO:0007165 | signal transduction | 21873635 | Process |
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Spatial pattern events for NDRG3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| NDRG3 | Human | Brain | rep_9 | 33558695 | 3.17e-12 |
| NDRG3 | Human | Brain | rep_10 | 33558695 | 5.75e-15 |
| NDRG3 | Human | Brain | rep_11 | 33558695 | 1.60e-07 |
| NDRG3 | Human | Brain | rep_12 | 33558695 | 6.34e-11 |
| NDRG3 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| NDRG3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| NDRG3 | Human | Breast | CID44971 | 34493872 | 4.85e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_9_H&E  |  |
Brain_rep_10_H&E  |  |
Brain_rep_11_H&E  |  |
Brain_rep_12_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Breast_CID44971_H&E  |  |
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Spatial pattern pathway has NDRG3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| NDRG3 | GOBP_Cell_Growth | Human | Brain | rep_4 | 1.0e-14 |
| NDRG3 | GOBP_Growth | Human | Brain | rep_4 | 1.0e-14 |
| NDRG3 | GOBP_Cell_Growth | Human | Liver | rep_1 | 2.1e-52 |
| NDRG3 | GOBP_Growth | Human | Liver | rep_1 | 2.1e-52 |
| NDRG3 | GOBP_Cell_Growth | Human | Intestine | rep_colon2 | 1.5e-57 |
| NDRG3 | GOBP_Growth | Human | Intestine | rep_colon2 | 1.5e-57 |
| NDRG3 | GOBP_Cell_Growth | Human | Intestine | A3 | 1.3e-16 |
| NDRG3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Intestine | A3 | 2.7e-15 |
| NDRG3 | GOBP_Gamete_Generation | Human | Intestine | A3 | 4.2e-13 |
| NDRG3 | GOBP_Growth | Human | Intestine | A3 | 3.3e-16 |
| NDRG3 | GOBP_Male_Gamete_Generation | Human | Intestine | A3 | 4.8e-15 |
| NDRG3 | GOBP_Multicellular_Organism_Reproduction | Human | Intestine | A3 | 4.1e-15 |
| NDRG3 | GOBP_Negative_Regulation_Of_Cell_Growth | Human | Intestine | A3 | 2.6e-16 |
| NDRG3 | GOBP_Regulation_Of_Growth | Human | Intestine | A3 | 3.6e-10 |
| NDRG3 | GOBP_Reproduction | Human | Intestine | A3 | 4.6e-19 |
| NDRG3 | GOBP_Negative_Regulation_Of_Growth | Human | Intestine | A8 | 3.4e-21 |
| NDRG3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Uterus | rep_1 | 1.6e-06 |
| NDRG3 | GOBP_Gamete_Generation | Human | Uterus | rep_26 | 3.8e-10 |
| NDRG3 | GOBP_Male_Gamete_Generation | Human | Uterus | rep_26 | 7.4e-14 |
| NDRG3 | GOBP_Negative_Regulation_Of_Cell_Growth | Human | Uterus | rep_26 | 3.0e-09 |
| NDRG3 | GOBP_Negative_Regulation_Of_Growth | Human | Uterus | rep_26 | 2.4e-09 |
| NDRG3 | GOBP_Cell_Growth | Human | Breast | rep_1 | 6.0e-15 |
| NDRG3 | GOBP_Regulation_Of_Growth | Human | Breast | rep_1 | 2.3e-04 |
| NDRG3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Breast | rep_5 | 1.5e-12 |
| NDRG3 | GOBP_Growth | Human | Breast | rep_5 | 5.4e-12 |
| NDRG3 | GOBP_Multicellular_Organism_Reproduction | Human | Breast | rep_5 | 8.1e-07 |
| NDRG3 | GOBP_Reproduction | Human | Breast | rep_5 | 8.1e-06 |
| NDRG3 | GOBP_Gamete_Generation | Human | Breast | rep_6 | 7.3e-08 |
| NDRG3 | GOBP_Male_Gamete_Generation | Human | Breast | rep_6 | 4.3e-06 |
| NDRG3 | GOBP_Cell_Growth | Human | Skin | P9_rep3 | 4.1e-08 |
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NDRG3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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NDRG3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for NDRG3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for NDRG3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NDRG3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
