|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: WDR18 (spascer ID:57418) |
Gene summary for WDR18 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | WDR18 | Gene ID | 57418 |
| Gene name | WD repeat domain 18 |
| Synonyms | Ipi3|R32184_1 |
| Cytomap | 19p13.3 |
| Type of gene | protein-coding |
| Description | WD repeat-containing protein 18Involved in Processing ITS2 3 homolog |
| Modification date | 20220513 |
| UniProtAcc | Q9BV38 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| WDR18 | GO:0005656 | nuclear pre-replicative complex | 21873635 | Component |
| WDR18 | GO:0006261 | DNA-templated DNA replication | 21873635 | Process |
| WDR18 | GO:0006364 | rRNA processing | 21873635 | Process |
| WDR18 | GO:0097344 | Rix1 complex | 21873635 | Component |
Top |
Spatial pattern events for WDR18 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| WDR18 | Human | Intestine | rep_colon2 | 34417225 | 2.00e-07 |
| WDR18 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| WDR18 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| WDR18 | Human | Liver | rep_liver4 | 34417225 | 1.39e-15 |
| WDR18 | Human | Intestine | A1 | 33406409 | 2.09e-15 |
| WDR18 | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| WDR18 | Human | Uterus | rep_2 | 34857954 | 3.12e-08 |
| WDR18 | Human | Uterus | rep_3 | 34857954 | 1.05e-09 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon2_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Top |
Spatial pattern pathway has WDR18 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| WDR18 | GOBP_Dna_Dependent_Dna_Replication | Human | Bladder | rep_4 | 5.7e-05 |
| WDR18 | GOBP_Ribosome_Biogenesis | Human | Intestine | A1 | 6.5e-08 |
| WDR18 | GOBP_Dna_Dependent_Dna_Replication | Human | Intestine | A3 | 2.2e-07 |
| WDR18 | GOBP_Dna_Metabolic_Process | Human | Intestine | A3 | 1.2e-09 |
| WDR18 | GOBP_Dna_Replication | Human | Intestine | A3 | 2.5e-08 |
| WDR18 | GOBP_Ncrna_Metabolic_Process | Human | Intestine | A3 | 8.6e-07 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication | Human | Intestine | A3 | 3.7e-07 |
| WDR18 | GOBP_Regulation_Of_Dna_Metabolic_Process | Human | Intestine | A3 | 2.8e-10 |
| WDR18 | GOBP_Regulation_Of_Dna_Replication | Human | Intestine | A3 | 2.9e-12 |
| WDR18 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication_Initiation | Human | Intestine | A8 | 3.4e-19 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication | Human | Pancreas | PDAC-B-st1 | 5.8e-06 |
| WDR18 | GOBP_Ncrna_Processing | Human | Uterus | rep_1 | 4.5e-06 |
| WDR18 | GOBP_Ribosome_Biogenesis | Human | Uterus | rep_1 | 9.5e-06 |
| WDR18 | GOBP_Rrna_Metabolic_Process | Human | Uterus | rep_1 | 2.4e-07 |
| WDR18 | GOBP_Dna_Replication_Initiation | Human | Uterus | rep_25 | 3.5e-10 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication_Initiation | Human | Uterus | rep_25 | 1.6e-12 |
| WDR18 | GOBP_Dna_Dependent_Dna_Replication | Human | Uterus | rep_26 | 2.7e-14 |
| WDR18 | GOBP_Dna_Replication | Human | Uterus | rep_26 | 1.5e-09 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication | Human | Uterus | rep_26 | 2.3e-09 |
| WDR18 | GOBP_Regulation_Of_Dna_Metabolic_Process | Human | Uterus | rep_26 | 2.1e-06 |
| WDR18 | GOBP_Regulation_Of_Dna_Replication | Human | Uterus | rep_26 | 1.5e-08 |
| WDR18 | GOBP_Dna_Dependent_Dna_Replication | Human | Breast | rep_6 | 5.7e-04 |
| WDR18 | GOBP_Dna_Metabolic_Process | Human | Breast | rep_6 | 1.4e-10 |
| WDR18 | GOBP_Dna_Replication | Human | Breast | rep_6 | 3.5e-07 |
| WDR18 | GOBP_Dna_Replication_Initiation | Human | Breast | rep_6 | 3.9e-07 |
| WDR18 | GOBP_Ncrna_Metabolic_Process | Human | Breast | rep_6 | 1.9e-04 |
| WDR18 | GOBP_Ncrna_Processing | Human | Breast | rep_6 | 1.3e-05 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication | Human | Breast | rep_6 | 2.1e-08 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication_Initiation | Human | Breast | rep_6 | 1.0e-04 |
| WDR18 | GOBP_Regulation_Of_Dna_Metabolic_Process | Human | Breast | rep_6 | 9.5e-08 |
| WDR18 | GOBP_Regulation_Of_Dna_Replication | Human | Breast | rep_6 | 1.8e-08 |
| WDR18 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| WDR18 | GOBP_Ribosome_Biogenesis | Human | Breast | rep_6 | 2.0e-06 |
| WDR18 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| WDR18 | GOBP_Rrna_Metabolic_Process | Human | Breast | rep_6 | 4.0e-06 |
| WDR18 | GOBP_Regulation_Of_Dna_Dependent_Dna_Replication | Human | Skin | P5_rep3 | 4.0e-08 |
Top |
WDR18 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
WDR18 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for WDR18 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for WDR18 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for WDR18 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
