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Spatial pattern gene: KYAT3 (spascer ID:56267) |
Gene summary for KYAT3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | KYAT3 | Gene ID | 56267 |
| Gene name | kynurenine aminotransferase 3 |
| Synonyms | CCBL2|KAT3|KATIII |
| Cytomap | 1p22.2 |
| Type of gene | protein-coding |
| Description | kynurenine--oxoglutarate transaminase 3cysteine-S-conjugate beta-lyase 2kynurenine aminotransferase IIIkynurenine--glyoxylate transaminasekynurenine--oxoglutarate transaminase III |
| Modification date | 20220513 |
| UniProtAcc | Q6YP21 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| KYAT3 | GO:0005737 | cytoplasm | 21873635 | Component |
| KYAT3 | GO:0005739 | mitochondrion | 21873635 | Component |
| KYAT3 | GO:0016212 | kynurenine-oxoglutarate transaminase activity | 21873635 | Function |
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Spatial pattern events for KYAT3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| KYAT3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver2_H&E  |  |
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Spatial pattern pathway has KYAT3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| KYAT3 | GOBP_L_Kynurenine_Metabolic_Process | Human | Bladder | rep_3 | 1.0e-05 |
| KYAT3 | GOBP_Alpha_Amino_Acid_Metabolic_Process | Human | Intestine | A8 | 7.0e-13 |
| KYAT3 | GOBP_Benzene_Containing_Compound_Metabolic_Process | Human | Intestine | A8 | 6.1e-26 |
| KYAT3 | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Intestine | A8 | 5.3e-13 |
| KYAT3 | GOBP_Cellular_Ketone_Metabolic_Process | Human | Intestine | A8 | 1.2e-11 |
| KYAT3 | GOBP_Dicarboxylic_Acid_Metabolic_Process | Human | Intestine | A8 | 2.6e-15 |
| KYAT3 | GOBP_Organic_Acid_Metabolic_Process | Human | Intestine | A8 | 2.5e-18 |
| KYAT3 | GOBP_Small_Molecule_Metabolic_Process | Human | Intestine | A8 | 2.1e-15 |
| KYAT3 | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Pancreas | PDAC-A-st2 | 9.6e-05 |
| KYAT3 | GOBP_Benzene_Containing_Compound_Metabolic_Process | Human | Uterus | rep_25 | 1.2e-08 |
| KYAT3 | GOBP_Kynurenine_Metabolic_Process | Human | Uterus | rep_25 | 1.3e-08 |
| KYAT3 | GOBP_L_Kynurenine_Metabolic_Process | Human | Uterus | rep_25 | 6.5e-08 |
| KYAT3 | GOBP_2_Oxoglutarate_Metabolic_Process | Human | Uterus | rep_26 | 3.0e-14 |
| KYAT3 | GOBP_Alpha_Amino_Acid_Metabolic_Process | Human | Uterus | rep_26 | 1.6e-06 |
| KYAT3 | GOBP_Cellular_Ketone_Metabolic_Process | Human | Uterus | rep_26 | 3.2e-13 |
| KYAT3 | GOBP_Organic_Acid_Metabolic_Process | Human | Uterus | rep_26 | 4.9e-06 |
| KYAT3 | GOBP_Benzene_Containing_Compound_Metabolic_Process | Human | Breast | rep_1 | 1.5e-21 |
| KYAT3 | GOBP_Cellular_Ketone_Metabolic_Process | Human | Breast | rep_1 | 6.1e-19 |
| KYAT3 | GOBP_Kynurenine_Metabolic_Process | Human | Breast | rep_1 | 6.1e-04 |
| KYAT3 | GOBP_L_Kynurenine_Metabolic_Process | Human | Breast | rep_5 | 6.2e-04 |
| KYAT3 | GOBP_Alpha_Amino_Acid_Metabolic_Process | Human | Breast | rep_6 | 1.7e-08 |
| KYAT3 | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Breast | rep_6 | 1.0e-10 |
| KYAT3 | GOBP_Organic_Acid_Metabolic_Process | Human | Breast | rep_6 | 6.7e-05 |
| KYAT3 | GOBP_Small_Molecule_Metabolic_Process | Human | Breast | rep_6 | 5.5e-09 |
| KYAT3 | GOBP_Cellular_Ketone_Metabolic_Process | Human | Lung | rep_2 | 2.1e-09 |
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KYAT3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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KYAT3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for KYAT3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for KYAT3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| KYAT3 | Q6YP21 | DB00114 | Pyridoxal phosphate | Kynurenine--oxoglutarate transaminase 3 | SmallMoleculeDrug | approved|investigational|nutraceutical |
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Related Diseases for KYAT3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
