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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: MEPCE (spascer ID:56257)

Gene summary for MEPCE

Gene summary

Gene information
	Species	Human
	Gene symbol	MEPCE
	Gene ID	56257
	Gene name	methylphosphate capping enzyme
	Synonyms	BCDIN3
	Cytomap	7q22.1
	Type of gene	protein-coding
	Description	7SK snRNA methylphosphate capping enzymebicoid-interacting protein 3 homologbin3 homologbin3, bicoid-interacting 3, homolog
	Modification date	20220513
	UniProtAcc	Q7L2J0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
MEPCE	GO:0008171	O-methyltransferase activity	21873635	Function
MEPCE	GO:0008173	RNA methyltransferase activity	21873635	Function
MEPCE	GO:0017069	snRNA binding	21873635	Function
MEPCE	GO:0040031	snRNA modification	21873635	Process

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Spatial pattern events for MEPCE

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
MEPCE	Human	Liver	rep_liver1	34417225	9.57e-08
MEPCE	Human	Intestine	A2	33406409	1.19e-09
MEPCE	Human	Uterus	rep_3	34857954	1.66e-15
MEPCE	Human	Breast	CID44971	34493872	2.25e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Intestine_A2_H&E
Uterus_rep_3_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has MEPCE envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
MEPCE	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Brain	rep_1	7.4e-34
MEPCE	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
MEPCE	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Liver	rep_1	1.5e-73
MEPCE	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
MEPCE	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
MEPCE	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
MEPCE	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
MEPCE	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
MEPCE	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
MEPCE	GOBP_Methylation	Human	Intestine	A3	5.9e-09
MEPCE	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
MEPCE	GOBP_Ncrna_Metabolic_Process	Human	Intestine	A3	8.6e-07
MEPCE	GOBP_Ncrna_Transcription	Human	Intestine	A3	1.7e-11
MEPCE	GOBP_Negative_Regulation_Of_Binding	Human	Intestine	A3	6.2e-10
MEPCE	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
MEPCE	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
MEPCE	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Intestine	A3	1.9e-13
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	1.3e-18
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
MEPCE	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	2.6e-15
MEPCE	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
MEPCE	GOBP_Positive_Regulation_Of_Protein_Localization_To_Nucleus	Human	Intestine	A3	2.5e-07
MEPCE	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
MEPCE	GOBP_Protein_Localization_To_Nucleus	Human	Intestine	A3	7.7e-09
MEPCE	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
MEPCE	GOBP_Regulation_Of_Binding	Human	Intestine	A3	4.9e-11
MEPCE	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
MEPCE	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
MEPCE	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
MEPCE	GOBP_Regulation_Of_Cellular_Localization	Human	Intestine	A3	4.5e-11
MEPCE	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
MEPCE	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
MEPCE	GOBP_Rna_Methylation	Human	Intestine	A3	2.7e-07
MEPCE	GOBP_Rna_Modification	Human	Intestine	A3	4.5e-10
MEPCE	GOBP_Cell_Cycle_G1_S_Phase_Transition	Human	Intestine	A8	8.5e-07
MEPCE	GOBP_Negative_Regulation_Of_Chromatin_Binding	Human	Intestine	A8	2.6e-12
MEPCE	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Intestine	A8	4.6e-12
MEPCE	GOBP_Protein_Localization_To_Nucleoplasm	Human	Intestine	A8	6.4e-08
MEPCE	GOBP_Regulation_Of_Snrna_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A8	1.8e-13
MEPCE	GOBP_Snrna_Metabolic_Process	Human	Intestine	A8	1.1e-12
MEPCE	GOBP_Snrna_Modification	Human	Intestine	A8	2.1e-12
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
MEPCE	GOBP_Ncrna_Transcription	Human	Pancreas	PDAC-A-st2	1.1e-05
MEPCE	GOBP_Protein_Localization_To_Nucleoplasm	Human	Pancreas	PDAC-A-st2	1.2e-06
MEPCE	GOBP_Snrna_Metabolic_Process	Human	Pancreas	PDAC-A-st2	4.8e-06
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_1	6.5e-06
MEPCE	GOBP_Regulation_Of_Snrna_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_2	6.3e-07
MEPCE	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
MEPCE	GOBP_Methylation	Human	Uterus	rep_26	1.9e-06
MEPCE	GOBP_Ncrna_Transcription	Human	Uterus	rep_26	3.8e-12
MEPCE	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
MEPCE	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Uterus	rep_26	5.6e-06
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
MEPCE	GOBP_Positive_Regulation_Of_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	3.2e-09
MEPCE	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.1e-08
MEPCE	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
MEPCE	GOBP_Regulation_Of_Chromatin_Binding	Human	Uterus	rep_26	7.2e-12
MEPCE	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
MEPCE	GOBP_Rna_Methylation	Human	Uterus	rep_26	6.8e-13
MEPCE	GOBP_Snrna_Metabolic_Process	Human	Uterus	rep_26	2.7e-06
MEPCE	GOBP_Negative_Regulation_Of_Binding	Human	Uterus	rep_29	3.5e-06
MEPCE	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Uterus	rep_29	1.6e-12
MEPCE	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
MEPCE	GOBP_Negative_Regulation_Of_Binding	Human	Breast	rep_1	3.4e-104
MEPCE	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Breast	rep_1	7.1e-11
MEPCE	GOBP_Regulation_Of_Binding	Human	Breast	rep_1	6.1e-11
MEPCE	GOBP_Regulation_Of_Cellular_Localization	Human	Breast	rep_1	5.5e-07
MEPCE	GOBP_Regulation_Of_Chromatin_Binding	Human	Breast	rep_1	2.5e-11
MEPCE	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
MEPCE	GOBP_Regulation_Of_Snrna_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_1	1.8e-62
MEPCE	GOBP_Snrna_Transcription	Human	Breast	rep_1	3.9e-07
MEPCE	GOBP_Negative_Regulation_Of_Chromatin_Binding	Human	Breast	rep_5	1.4e-05
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_5	1.1e-11
MEPCE	GOBP_Positive_Regulation_Of_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Breast	rep_5	1.4e-14
MEPCE	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
MEPCE	GOBP_Protein_Localization_To_Nucleus	Human	Breast	rep_5	1.3e-04
MEPCE	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
MEPCE	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
MEPCE	GOBP_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_6	3.5e-11
MEPCE	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
MEPCE	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
MEPCE	GOBP_Methylation	Human	Breast	rep_6	1.7e-06
MEPCE	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
MEPCE	GOBP_Ncrna_Metabolic_Process	Human	Breast	rep_6	1.9e-04
MEPCE	GOBP_Ncrna_Transcription	Human	Breast	rep_6	6.3e-09
MEPCE	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
MEPCE	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
MEPCE	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	1.4e-09
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
MEPCE	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	2.5e-13
MEPCE	GOBP_Positive_Regulation_Of_Protein_Localization_To_Nucleus	Human	Breast	rep_6	2.8e-06
MEPCE	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
MEPCE	GOBP_Protein_Localization_To_Nuclear_Body	Human	Breast	rep_6	9.4e-13
MEPCE	GOBP_Protein_Localization_To_Nucleoplasm	Human	Breast	rep_6	3.3e-10
MEPCE	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
MEPCE	GOBP_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_6	2.8e-06
MEPCE	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
MEPCE	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
MEPCE	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
MEPCE	GOBP_Regulation_Of_Protein_Localization_To_Nucleus	Human	Breast	rep_6	8.7e-06
MEPCE	GOBP_Rna_Methylation	Human	Breast	rep_6	3.8e-05
MEPCE	GOBP_Rna_Modification	Human	Breast	rep_6	1.0e-04
MEPCE	GOBP_Snrna_Metabolic_Process	Human	Breast	rep_6	2.1e-04
MEPCE	GOBP_Positive_Regulation_Of_Protein_Localization_To_Nucleus	Human	Skin	P2_rep2	1.7e-09
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
MEPCE	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
MEPCE	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Skin	P5_rep1	8.2e-10
MEPCE	GOBP_Snrna_Metabolic_Process	Human	Skin	P5_rep1	2.0e-08
MEPCE	GOBP_Negative_Regulation_Of_Chromatin_Binding	Human	Skin	P10_rep1	3.8e-09
MEPCE	GOBP_Regulation_Of_Chromatin_Binding	Human	Skin	P10_rep1	4.4e-09
MEPCE	GOBP_Snrna_Transcription	Human	Skin	P10_rep1	2.0e-08
MEPCE	GOBP_Regulation_Of_Snrna_Transcription_By_Rna_Polymerase_Ii	Human	Skin	P10_rep2	6.6e-24
MEPCE	GOBP_Snrna_Modification	Human	Skin	P10_rep2	2.4e-12

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MEPCE function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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MEPCE function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for MEPCE envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for MEPCE

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for MEPCE

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source