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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ANAPC5 (spascer ID:51433)

Gene summary for ANAPC5

Gene summary

Gene information
	Species	Human
	Gene symbol	ANAPC5
	Gene ID	51433
	Gene name	anaphase promoting complex subunit 5
	Synonyms	APC5
	Cytomap	12q24.31
	Type of gene	protein-coding
	Description	anaphase-promoting complex subunit 5cyclosome subunit 5
	Modification date	20220513
	UniProtAcc	Q9UJX4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ANAPC5	GO:0005680	anaphase-promoting complex	21873635	Component
ANAPC5	GO:0031145	anaphase-promoting complex-dependent catabolic process	21873635	Process
ANAPC5	GO:0045842	positive regulation of mitotic metaphase/anaphase transition	21873635	Process
ANAPC5	GO:0070979	protein K11-linked ubiquitination	21873635	Process

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Spatial pattern events for ANAPC5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ANAPC5	Human	Brain	rep_9	33558695	3.01e-15
ANAPC5	Human	Brain	rep_10	33558695	9.97e-10
ANAPC5	Human	Brain	rep_11	33558695	1.62e-06
ANAPC5	Human	Intestine	rep_colon1	34417225	2.67e-09
ANAPC5	Human	Intestine	rep_colon2	34417225	8.12e-16
ANAPC5	Human	Intestine	rep_colon3	34417225	5.68e-10
ANAPC5	Human	Liver	rep_liver1	34417225	4.52e-14
ANAPC5	Human	Liver	rep_liver2	34417225	6.98e-16
ANAPC5	Human	Liver	rep_liver4	34417225	7.71e-16
ANAPC5	Human	Intestine	A2	33406409	3.80e-09
ANAPC5	Human	Skin	P5_rep2	32946785	7.92e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A2_H&E
Skin_P5_rep2_H&E

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Spatial pattern pathway has ANAPC5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ANAPC5	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
ANAPC5	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
ANAPC5	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
ANAPC5	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
ANAPC5	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
ANAPC5	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
ANAPC5	GOBP_Cell_Division	Human	Intestine	A3	2.7e-10
ANAPC5	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
ANAPC5	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
ANAPC5	GOBP_Chromosome_Segregation	Human	Intestine	A3	4.7e-12
ANAPC5	GOBP_Chromosome_Separation	Human	Intestine	A3	2.3e-07
ANAPC5	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
ANAPC5	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
ANAPC5	GOBP_Mitotic_Nuclear_Division	Human	Intestine	A3	5.1e-12
ANAPC5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Intestine	A3	6.7e-13
ANAPC5	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Intestine	A3	7.7e-11
ANAPC5	GOBP_Nuclear_Chromosome_Segregation	Human	Intestine	A3	4.3e-09
ANAPC5	GOBP_Organelle_Fission	Human	Intestine	A3	3.4e-16
ANAPC5	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	1.3e-18
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
ANAPC5	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	2.6e-15
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Nuclear_Division	Human	Intestine	A3	2.6e-11
ANAPC5	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
ANAPC5	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Intestine	A3	4.6e-13
ANAPC5	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
ANAPC5	GOBP_Protein_Polyubiquitination	Human	Intestine	A3	2.1e-10
ANAPC5	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
ANAPC5	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
ANAPC5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
ANAPC5	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
ANAPC5	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
ANAPC5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
ANAPC5	GOBP_Regulation_Of_Mitotic_Nuclear_Division	Human	Intestine	A3	1.2e-13
ANAPC5	GOBP_Regulation_Of_Nuclear_Division	Human	Intestine	A3	5.5e-11
ANAPC5	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
ANAPC5	GOBP_Sister_Chromatid_Segregation	Human	Intestine	A3	1.0e-11
ANAPC5	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Intestine	A8	9.8e-07
ANAPC5	GOBP_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Intestine	A8	1.0e-15
ANAPC5	GOBP_Positive_Regulation_Of_Chromosome_Separation	Human	Intestine	A8	4.6e-13
ANAPC5	GOBP_Positive_Regulation_Of_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Intestine	A8	6.9e-21
ANAPC5	GOBP_Positive_Regulation_Of_Nuclear_Division	Human	Intestine	A8	7.4e-11
ANAPC5	GOBP_Regulation_Of_Chromosome_Segregation	Human	Intestine	A8	4.3e-08
ANAPC5	GOBP_Regulation_Of_Chromosome_Separation	Human	Intestine	A8	1.3e-16
ANAPC5	GOBP_Cell_Division	Human	Pancreas	PDAC-B-st1	5.8e-05
ANAPC5	GOBP_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
ANAPC5	GOBP_Nuclear_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
ANAPC5	GOBP_Organelle_Fission	Human	Pancreas	PDAC-B-st1	3.9e-05
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Nuclear_Division	Human	Pancreas	PDAC-B-st1	2.0e-05
ANAPC5	GOBP_Positive_Regulation_Of_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Pancreas	PDAC-A-st2	5.0e-05
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_1	6.5e-06
ANAPC5	GOBP_Protein_Polyubiquitination	Human	Uterus	rep_25	1.1e-17
ANAPC5	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
ANAPC5	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
ANAPC5	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
ANAPC5	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
ANAPC5	GOBP_Chromosome_Segregation	Human	Uterus	rep_26	5.6e-19
ANAPC5	GOBP_Chromosome_Separation	Human	Uterus	rep_26	1.2e-11
ANAPC5	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
ANAPC5	GOBP_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Uterus	rep_26	1.9e-09
ANAPC5	GOBP_Mitotic_Nuclear_Division	Human	Uterus	rep_26	2.4e-07
ANAPC5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Uterus	rep_26	4.0e-12
ANAPC5	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	1.1e-07
ANAPC5	GOBP_Nuclear_Chromosome_Segregation	Human	Uterus	rep_26	1.5e-12
ANAPC5	GOBP_Organelle_Fission	Human	Uterus	rep_26	6.0e-11
ANAPC5	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
ANAPC5	GOBP_Positive_Regulation_Of_Chromosome_Separation	Human	Uterus	rep_26	9.8e-12
ANAPC5	GOBP_Positive_Regulation_Of_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Uterus	rep_26	1.4e-10
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.1e-08
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Nuclear_Division	Human	Uterus	rep_26	9.8e-11
ANAPC5	GOBP_Positive_Regulation_Of_Nuclear_Division	Human	Uterus	rep_26	8.8e-07
ANAPC5	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
ANAPC5	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Uterus	rep_26	2.2e-12
ANAPC5	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
ANAPC5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
ANAPC5	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
ANAPC5	GOBP_Regulation_Of_Chromosome_Segregation	Human	Uterus	rep_26	3.3e-08
ANAPC5	GOBP_Regulation_Of_Chromosome_Separation	Human	Uterus	rep_26	3.6e-11
ANAPC5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
ANAPC5	GOBP_Regulation_Of_Nuclear_Division	Human	Uterus	rep_26	1.4e-09
ANAPC5	GOBP_Sister_Chromatid_Segregation	Human	Uterus	rep_26	3.3e-13
ANAPC5	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
ANAPC5	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
ANAPC5	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Nuclear_Division	Human	Breast	rep_5	2.6e-05
ANAPC5	GOBP_Positive_Regulation_Of_Nuclear_Division	Human	Breast	rep_5	9.7e-14
ANAPC5	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
ANAPC5	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
ANAPC5	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
ANAPC5	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
ANAPC5	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
ANAPC5	GOBP_Cell_Division	Human	Breast	rep_6	8.2e-07
ANAPC5	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
ANAPC5	GOBP_Chromosome_Segregation	Human	Breast	rep_6	1.9e-05
ANAPC5	GOBP_Chromosome_Separation	Human	Breast	rep_6	4.1e-08
ANAPC5	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
ANAPC5	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
ANAPC5	GOBP_Mitotic_Nuclear_Division	Human	Breast	rep_6	2.5e-08
ANAPC5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Breast	rep_6	4.0e-04
ANAPC5	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Breast	rep_6	2.2e-09
ANAPC5	GOBP_Nuclear_Chromosome_Segregation	Human	Breast	rep_6	4.6e-06
ANAPC5	GOBP_Organelle_Fission	Human	Breast	rep_6	3.0e-05
ANAPC5	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	1.4e-09
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
ANAPC5	GOBP_Positive_Regulation_Of_Chromosome_Separation	Human	Breast	rep_6	1.4e-05
ANAPC5	GOBP_Positive_Regulation_Of_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Breast	rep_6	2.0e-11
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	2.5e-13
ANAPC5	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
ANAPC5	GOBP_Proteasomal_Protein_Catabolic_Process	Human	Breast	rep_6	6.8e-09
ANAPC5	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
ANAPC5	GOBP_Protein_K11_Linked_Ubiquitination	Human	Breast	rep_6	1.6e-06
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
ANAPC5	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
ANAPC5	GOBP_Protein_Polyubiquitination	Human	Breast	rep_6	6.3e-04
ANAPC5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
ANAPC5	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
ANAPC5	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
ANAPC5	GOBP_Regulation_Of_Chromosome_Segregation	Human	Breast	rep_6	2.6e-07
ANAPC5	GOBP_Regulation_Of_Chromosome_Separation	Human	Breast	rep_6	3.3e-05
ANAPC5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
ANAPC5	GOBP_Regulation_Of_Mitotic_Nuclear_Division	Human	Breast	rep_6	1.6e-05
ANAPC5	GOBP_Regulation_Of_Nuclear_Division	Human	Breast	rep_6	3.4e-06
ANAPC5	GOBP_Sister_Chromatid_Segregation	Human	Breast	rep_6	5.3e-04
ANAPC5	GOBP_Anaphase_Promoting_Complex_Dependent_Catabolic_Process	Human	Skin	P5_rep1	5.7e-11
ANAPC5	GOBP_Nuclear_Chromosome_Segregation	Human	Skin	P5_rep1	7.9e-09
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
ANAPC5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Skin	P5_rep1	8.2e-10
ANAPC5	GOBP_Positive_Regulation_Of_Mitotic_Nuclear_Division	Human	Skin	P5_rep1	2.4e-13
ANAPC5	GOBP_Positive_Regulation_Of_Nuclear_Division	Human	Skin	P5_rep1	1.7e-09
ANAPC5	GOBP_Organelle_Fission	Human	Skin	P5_rep3	1.0e-09
ANAPC5	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
ANAPC5	GOBP_Positive_Regulation_Of_Metaphase_Anaphase_Transition_Of_Cell_Cycle	Human	Skin	P10_rep1	1.0e-11

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ANAPC5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ANAPC5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ANAPC5 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ANAPC5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ANAPC5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source