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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: NIP7 (spascer ID:51388)

Gene summary for NIP7

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

NIP7

Gene ID

51388

Gene namenucleolar pre-rRNA processing protein NIP7
SynonymsCGI-37|HSPC031|KD93
Cytomap16q22.1
Type of geneprotein-coding
Description60S ribosome subunit biogenesis protein NIP7 homologNIP7, nucleolar pre-rRNA processing proteinnuclear import 7 homolog
Modification date20220513
UniProtAcc

Q9Y221


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
NIP7

GO:0005730

nucleolus

21873635

Component
NIP7

GO:0030687

preribosome, large subunit precursor

21873635

Component
NIP7

GO:0042273

ribosomal large subunit biogenesis

21873635

Process

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Spatial pattern events for NIP7

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
NIP7HumanIntestinerep_colon1 344172253.42e-15
NIP7HumanLiverrep_liver1 344172251.08e-15
NIP7HumanLiverrep_liver2 344172256.98e-16
NIP7HumanUterusrep_3 348579543.12e-11
NIP7HumanSkinP2_rep3 329467851.94e-06

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot
Skin_P2_rep3_H&E
boxplot

boxplot


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Spatial pattern pathway has NIP7 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
NIP7GOBP_Ribosomal_Large_Subunit_BiogenesisHumanIntestineA1 4.4e-09
NIP7GOBP_Ribosome_AssemblyHumanIntestineA1 2.8e-16
NIP7GOBP_Ribosome_BiogenesisHumanIntestineA1 6.5e-08
NIP7GOBP_Ribosomal_Large_Subunit_BiogenesisHumanPancreasPDAC-B-st1 5.3e-05
NIP7GOBP_Ribosome_BiogenesisHumanUterusrep_1 9.5e-06
NIP7GOBP_Ribosomal_Large_Subunit_BiogenesisHumanUterusrep_26 1.5e-07
NIP7GOBP_Ribosome_AssemblyHumanUterusrep_26 6.3e-19
NIP7GOBP_Organelle_AssemblyHumanBreastrep_6 2.3e-07
NIP7GOBP_Ribonucleoprotein_Complex_BiogenesisHumanBreastrep_6 1.3e-07
NIP7GOBP_Ribosomal_Large_Subunit_BiogenesisHumanBreastrep_6 2.7e-06
NIP7GOBP_Ribosome_AssemblyHumanBreastrep_6 7.2e-08
NIP7GOBP_Ribosome_BiogenesisHumanBreastrep_6 2.0e-06
NIP7GOBP_Ribosomal_Large_Subunit_BiogenesisHumanSkinP10_rep1 1.5e-10

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NIP7 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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NIP7 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for NIP7 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for NIP7

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NIP7

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource