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Spatial pattern gene: EIF3L (spascer ID:51386) |
Gene summary for EIF3L |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | EIF3L | Gene ID | 51386 |
| Gene name | eukaryotic translation initiation factor 3 subunit L |
| Synonyms | EIF3EIP|EIF3S11|EIF3S6IP|HSPC021|HSPC025|MSTP005 |
| Cytomap | 22q13.1 |
| Type of gene | protein-coding |
| Description | eukaryotic translation initiation factor 3 subunit LeIEF associated protein HSPC021eukaryotic translation initiation factor 3 subunit 6-interacting proteineukaryotic translation initiation factor 3 subunit E-interacting protein |
| Modification date | 20220513 |
| UniProtAcc | Q9Y262 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| EIF3L | GO:0005852 | eukaryotic translation initiation factor 3 complex | 21873635 | Component |
| EIF3L | GO:0006413 | translational initiation | 21873635 | Process |
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Spatial pattern events for EIF3L |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| EIF3L | Human | Bladder | rep_2 | 34385456 | 6.29e-15 |
| EIF3L | Human | Liver | rep_1 | 34792289 | 1.90e-07 |
| EIF3L | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| EIF3L | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| EIF3L | Human | Intestine | rep_colon3 | 34417225 | 1.90e-14 |
| EIF3L | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| EIF3L | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| EIF3L | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| EIF3L | Human | Liver | rep_liver3 | 34417225 | 1.15e-14 |
| EIF3L | Human | Intestine | A1 | 33406409 | 3.49e-15 |
| EIF3L | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| EIF3L | Human | Uterus | rep_1 | 34857954 | 8.93e-15 |
| EIF3L | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| EIF3L | Human | Uterus | rep_4 | 34857954 | 3.39e-15 |
| EIF3L | Human | Breast | 1160920F | 34493872 | 5.99e-06 |
| EIF3L | Human | Breast | CID4290 | 34493872 | 4.14e-13 |
| EIF3L | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_2_H&E  |  |
Liver_rep_1_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon3_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver3_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_1_H&E  |  |
Uterus_rep_3_H&E  |  |
Uterus_rep_4_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4290_H&E  |  |
Breast_CID44971_H&E  |  |
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Spatial pattern pathway has EIF3L envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| EIF3L | GOBP_Amide_Biosynthetic_Process | Human | Intestine | A1 | 6.4e-07 |
| EIF3L | GOBP_Cytoplasmic_Translation | Human | Intestine | A1 | 5.4e-14 |
| EIF3L | GOBP_Peptide_Biosynthetic_Process | Human | Intestine | A1 | 4.6e-10 |
| EIF3L | GOBP_Biological_Process_Involved_In_Symbiotic_Interaction | Human | Intestine | A3 | 3.5e-14 |
| EIF3L | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Intestine | A3 | 1.6e-07 |
| EIF3L | GOBP_Translational_Initiation | Human | Intestine | A3 | 5.0e-09 |
| EIF3L | GOBP_Viral_Translation | Human | Intestine | A3 | 9.4e-07 |
| EIF3L | GOBP_Viral_Gene_Expression | Human | Intestine | A8 | 1.8e-23 |
| EIF3L | GOBP_Biological_Process_Involved_In_Symbiotic_Interaction | Human | Uterus | rep_26 | 5.9e-08 |
| EIF3L | GOBP_Cytoplasmic_Translational_Initiation | Human | Uterus | rep_26 | 2.8e-10 |
| EIF3L | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Uterus | rep_26 | 4.6e-06 |
| EIF3L | GOBP_Viral_Translational_Termination_Reinitiation | Human | Uterus | rep_26 | 1.1e-07 |
| EIF3L | GOBP_Biological_Process_Involved_In_Symbiotic_Interaction | Human | Breast | rep_1 | 5.4e-30 |
| EIF3L | GOBP_Viral_Gene_Expression | Human | Breast | rep_5 | 4.2e-10 |
| EIF3L | GOBP_Amide_Biosynthetic_Process | Human | Breast | rep_6 | 8.7e-05 |
| EIF3L | GOBP_Cellular_Amide_Metabolic_Process | Human | Breast | rep_6 | 5.6e-05 |
| EIF3L | GOBP_Cytoplasmic_Translation | Human | Breast | rep_6 | 2.4e-06 |
| EIF3L | GOBP_Cytoplasmic_Translational_Initiation | Human | Breast | rep_6 | 3.6e-11 |
| EIF3L | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Human | Breast | rep_6 | 1.2e-09 |
| EIF3L | GOBP_Peptide_Biosynthetic_Process | Human | Breast | rep_6 | 1.6e-05 |
| EIF3L | GOBP_Peptide_Metabolic_Process | Human | Breast | rep_6 | 8.7e-05 |
| EIF3L | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| EIF3L | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Breast | rep_6 | 1.4e-08 |
| EIF3L | GOBP_Translational_Initiation | Human | Breast | rep_6 | 2.2e-09 |
| EIF3L | GOBP_Viral_Translation | Human | Breast | rep_6 | 1.4e-08 |
| EIF3L | GOBP_Viral_Translational_Termination_Reinitiation | Human | Breast | rep_6 | 2.1e-11 |
| EIF3L | GOBP_Biological_Process_Involved_In_Symbiotic_Interaction | Human | Skin | P9_rep2 | 4.7e-10 |
| EIF3L | GOBP_Viral_Translational_Termination_Reinitiation | Human | Skin | P10_rep1 | 2.0e-19 |
| EIF3L | GOBP_Biological_Process_Involved_In_Symbiotic_Interaction | Human | Lung | rep_1 | 2.4e-10 |
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EIF3L function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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EIF3L function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for EIF3L envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for EIF3L |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for EIF3L |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
