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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ATRAID (spascer ID:51374)

Gene summary for ATRAID

Gene summary

Gene information
	Species	Human
	Gene symbol	ATRAID
	Gene ID	51374
	Gene name	all-trans retinoic acid induced differentiation factor
	Synonyms	APR--3\|APR-3\|APR3\|C2orf28\|HSPC013\|PRO240\|p18
	Cytomap	2p23.3
	Type of gene	protein-coding
	Description	all-trans retinoic acid-induced differentiation factorapoptosis related protein APR-3apoptosis-related protein 3
	Modification date	20220513
	UniProtAcc	Q6UW56

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ATRAID	GO:0043231	intracellular membrane-bounded organelle	21873635	Component
ATRAID	GO:0045669	positive regulation of osteoblast differentiation	21873635	Process

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Spatial pattern events for ATRAID

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ATRAID	Human	Brain	rep_10	33558695	8.67e-06
ATRAID	Human	Intestine	rep_colon1	34417225	1.47e-07
ATRAID	Human	Intestine	rep_colon2	34417225	2.60e-07
ATRAID	Human	Intestine	rep_colon4	34417225	8.95e-08
ATRAID	Human	Liver	rep_liver1	34417225	9.54e-12
ATRAID	Human	Liver	rep_liver2	34417225	6.98e-16
ATRAID	Human	Liver	rep_liver4	34417225	1.64e-09
ATRAID	Human	Uterus	rep_1	34857954	7.01e-13
ATRAID	Human	Uterus	rep_3	34857954	2.85e-09
ATRAID	Human	Breast	1160920F	34493872	1.48e-15
ATRAID	Human	Breast	CID44971	34493872	3.26e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_10_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Uterus_rep_1_H&E
Uterus_rep_3_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has ATRAID envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ATRAID	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	7.4e-34
ATRAID	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
ATRAID	GOBP_Bone_Mineralization	Human	Bladder	rep_2	6.1e-16
ATRAID	GOBP_Ossification	Human	Bladder	rep_2	1.1e-10
ATRAID	GOBP_Osteoblast_Differentiation	Human	Bladder	rep_2	3.8e-11
ATRAID	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.0e-70
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
ATRAID	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
ATRAID	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
ATRAID	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
ATRAID	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
ATRAID	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Intestine	A3	5.0e-10
ATRAID	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	5.4e-19
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Intestine	A3	9.0e-12
ATRAID	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Intestine	A3	3.2e-07
ATRAID	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	7.8e-11
ATRAID	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
ATRAID	GOBP_Osteoblast_Differentiation	Human	Intestine	A3	1.4e-08
ATRAID	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
ATRAID	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
ATRAID	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
ATRAID	GOBP_Regulation_Of_Catabolic_Process	Human	Intestine	A3	3.5e-16
ATRAID	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
ATRAID	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	7.2e-15
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
ATRAID	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Intestine	A3	1.2e-14
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Intestine	A8	1.5e-10
ATRAID	GOBP_Ossification	Human	Intestine	A8	3.0e-07
ATRAID	GOBP_Osteoblast_Proliferation	Human	Intestine	A8	4.3e-17
ATRAID	GOBP_Positive_Regulation_Of_Osteoblast_Differentiation	Human	Intestine	A8	1.9e-11
ATRAID	GOBP_Biomineralization	Human	Pancreas	PDAC-B-st1	8.7e-05
ATRAID	GOBP_Osteoblast_Differentiation	Human	Pancreas	PDAC-B-st1	7.4e-05
ATRAID	GOBP_Positive_Regulation_Of_Bone_Mineralization	Human	Pancreas	PDAC-A-st2	7.3e-05
ATRAID	GOBP_Positive_Regulation_Of_Ossification	Human	Pancreas	PDAC-A-st2	7.3e-05
ATRAID	GOBP_Regulation_Of_Biomineralization	Human	Pancreas	PDAC-A-st2	9.8e-05
ATRAID	GOBP_Osteoblast_Proliferation	Human	Uterus	rep_1	1.5e-06
ATRAID	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
ATRAID	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
ATRAID	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Uterus	rep_26	4.0e-09
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Uterus	rep_26	4.4e-10
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	9.6e-19
ATRAID	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Uterus	rep_26	1.3e-06
ATRAID	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
ATRAID	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
ATRAID	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
ATRAID	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	2.7e-10
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
ATRAID	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Uterus	rep_26	7.3e-06
ATRAID	GOBP_Osteoblast_Differentiation	Human	Uterus	rep_29	6.4e-07
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
ATRAID	GOBP_Positive_Regulation_Of_Osteoblast_Differentiation	Human	Uterus	rep_29	1.7e-09
ATRAID	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
ATRAID	GOBP_Regulation_Of_Osteoblast_Differentiation	Human	Uterus	rep_29	2.4e-10
ATRAID	GOBP_Biomineralization	Human	Breast	rep_1	5.6e-120
ATRAID	GOBP_Bone_Mineralization	Human	Breast	rep_1	9.6e-17
ATRAID	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	1.3e-54
ATRAID	GOBP_Osteoblast_Proliferation	Human	Breast	rep_1	5.4e-07
ATRAID	GOBP_Positive_Regulation_Of_Biomineralization	Human	Breast	rep_1	6.2e-45
ATRAID	GOBP_Positive_Regulation_Of_Bone_Mineralization	Human	Breast	rep_1	1.1e-24
ATRAID	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
ATRAID	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
ATRAID	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
ATRAID	GOBP_Positive_Regulation_Of_Ossification	Human	Breast	rep_1	1.3e-62
ATRAID	GOBP_Positive_Regulation_Of_Osteoblast_Differentiation	Human	Breast	rep_1	2.7e-28
ATRAID	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
ATRAID	GOBP_Regulation_Of_Osteoblast_Differentiation	Human	Breast	rep_1	4.2e-06
ATRAID	GOBP_Negative_Regulation_Of_Osteoblast_Proliferation	Human	Breast	rep_4	8.6e-09
ATRAID	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
ATRAID	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	4.3e-05
ATRAID	GOBP_Osteoblast_Differentiation	Human	Breast	rep_5	1.2e-07
ATRAID	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
ATRAID	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	2.0e-06
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Breast	rep_6	1.0e-06
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Breast	rep_6	4.8e-10
ATRAID	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Breast	rep_6	1.3e-04
ATRAID	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
ATRAID	GOBP_Ossification	Human	Breast	rep_6	8.4e-04
ATRAID	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
ATRAID	GOBP_Regulation_Of_Biomineralization	Human	Breast	rep_6	9.4e-05
ATRAID	GOBP_Regulation_Of_Bone_Mineralization	Human	Breast	rep_6	1.7e-04
ATRAID	GOBP_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	3.3e-04
ATRAID	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Breast	rep_6	6.2e-07
ATRAID	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Breast	rep_6	4.3e-04
ATRAID	GOBP_Negative_Regulation_Of_Osteoblast_Proliferation	Human	Skin	P10_rep2	4.9e-10
ATRAID	GOBP_Ossification	Human	Lung	rep_1	8.0e-09
ATRAID	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Lung	rep_2	3.4e-07
ATRAID	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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ATRAID function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ATRAID function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ATRAID envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ATRAID

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ATRAID

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source