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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: CDC40 (spascer ID:51362)

Gene summary for CDC40

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

CDC40

Gene ID

51362

Gene namecell division cycle 40
SynonymsEHB3|PCH15|PRP17|PRPF17
Cytomap6q21
Type of geneprotein-coding
Descriptionpre-mRNA-processing factor 17EH-binding protein 3PRP17 homologcell division cycle 40 homologhPRP17pre-mRNA splicing factor 17
Modification date20220513
UniProtAcc

O60508


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
CDC40

GO:0000398

mRNA splicing, via spliceosome

21873635

Process
CDC40

GO:0003729

mRNA binding

21873635

Function
CDC40

GO:0071013

catalytic step 2 spliceosome

21873635

Component

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Spatial pattern events for CDC40

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
CDC40HumanLiverrep_liver2 344172253.08e-14

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver2_H&E
boxplot

boxplot


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Spatial pattern pathway has CDC40 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
CDC40GOBP_Cellular_Macromolecule_LocalizationHumanIntestineA3 1.7e-09
CDC40GOBP_Establishment_Of_Protein_LocalizationHumanIntestineA3 5.0e-10
CDC40GOBP_Establishment_Of_Rna_LocalizationHumanIntestineA3 9.7e-11
CDC40GOBP_Intracellular_Protein_TransportHumanIntestineA3 4.8e-12
CDC40GOBP_Intracellular_TransportHumanIntestineA3 7.6e-15
CDC40GOBP_Mrna_3_End_ProcessingHumanIntestineA3 4.9e-12
CDC40GOBP_Mrna_Export_From_NucleusHumanIntestineA3 9.9e-15
CDC40GOBP_Mrna_Metabolic_ProcessHumanIntestineA3 7.7e-20
CDC40GOBP_Mrna_ProcessingHumanIntestineA3 4.9e-17
CDC40GOBP_Mrna_TransportHumanIntestineA3 6.6e-09
CDC40GOBP_Nuclear_ExportHumanIntestineA3 3.6e-07
CDC40GOBP_Nuclear_TransportHumanIntestineA3 5.6e-10
CDC40GOBP_Nucleobase_Containing_Compound_TransportHumanIntestineA3 2.5e-11
CDC40GOBP_Protein_Containing_Complex_LocalizationHumanIntestineA3 6.4e-12
CDC40GOBP_Rna_3_End_ProcessingHumanIntestineA3 9.2e-07
CDC40GOBP_Rna_Export_From_NucleusHumanIntestineA3 3.3e-10
CDC40GOBP_Rna_LocalizationHumanIntestineA3 1.4e-08
CDC40GOBP_Rna_ProcessingHumanIntestineA3 3.9e-09
CDC40GOBP_Rna_SplicingHumanIntestineA3 3.3e-19
CDC40GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanIntestineA3 2.2e-12
CDC40GOBP_Mrna_Metabolic_ProcessHumanPancreasPDAC-B-st1 2.6e-05
CDC40GOBP_Rna_Export_From_NucleusHumanPancreasPDAC-B-st1 6.7e-05
CDC40GOBP_Rna_SplicingHumanPancreasPDAC-B-st1 1.9e-05
CDC40GOBP_Mrna_Export_From_NucleusHumanPancreasPDAC-A-st2 3.9e-08
CDC40GOBP_Nuclear_ExportHumanUterusrep_25 7.4e-11
CDC40GOBP_Nuclear_TransportHumanUterusrep_25 2.3e-13
CDC40GOBP_Establishment_Of_Rna_LocalizationHumanUterusrep_26 8.7e-07
CDC40GOBP_Mrna_Export_From_NucleusHumanUterusrep_26 3.9e-08
CDC40GOBP_Rna_Export_From_NucleusHumanUterusrep_26 3.8e-10
CDC40GOBP_Rna_LocalizationHumanUterusrep_26 1.2e-09
CDC40GOBP_Rna_SplicingHumanUterusrep_26 1.0e-05
CDC40GOBP_Mrna_3_End_ProcessingHumanUterusrep_27 5.1e-08
CDC40GOBP_Cellular_Macromolecule_LocalizationHumanBreastrep_1 3.7e-09
CDC40GOBP_Establishment_Of_Protein_LocalizationHumanBreastrep_1 7.2e-05
CDC40GOBP_Intracellular_Protein_TransportHumanBreastrep_6 6.4e-12
CDC40GOBP_Intracellular_TransportHumanBreastrep_6 1.3e-08
CDC40GOBP_Mrna_3_End_ProcessingHumanBreastrep_6 6.6e-04
CDC40GOBP_Mrna_Export_From_NucleusHumanBreastrep_6 1.1e-04
CDC40GOBP_Mrna_Metabolic_ProcessHumanBreastrep_6 3.0e-08
CDC40GOBP_Mrna_ProcessingHumanBreastrep_6 1.5e-06
CDC40GOBP_Mrna_TransportHumanBreastrep_6 1.9e-10
CDC40GOBP_Nuclear_ExportHumanBreastrep_6 1.4e-05
CDC40GOBP_Nuclear_TransportHumanBreastrep_6 3.1e-08
CDC40GOBP_Protein_Containing_Complex_LocalizationHumanBreastrep_6 1.3e-06
CDC40GOBP_Rna_3_End_ProcessingHumanBreastrep_6 1.8e-05
CDC40GOBP_Rna_Export_From_NucleusHumanBreastrep_6 9.6e-09
CDC40GOBP_Rna_LocalizationHumanBreastrep_6 7.7e-05
CDC40GOBP_Rna_ProcessingHumanBreastrep_6 3.5e-06
CDC40GOBP_Rna_SplicingHumanBreastrep_6 1.1e-09
CDC40GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanBreastrep_6 5.4e-08
CDC40GOBP_Nuclear_TransportHumanSkinP5_rep1 5.0e-19
CDC40GOBP_Mrna_Metabolic_ProcessHumanSkinP5_rep3 1.8e-08
CDC40GOBP_Mrna_ProcessingHumanSkinP5_rep3 9.7e-09

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CDC40 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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CDC40 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for CDC40 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for CDC40

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CDC40

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource